STRINGSTRING
ube2j1 ube2j1 LOC102310624 LOC102310624 LOC102313398 LOC102313398 LOC102290203 LOC102290203 LOC102299096 LOC102299096 uba6 uba6 LOC102305568 LOC102305568 ube2k ube2k LOC102297909 LOC102297909 ubox5 ubox5 LOC102306884 LOC102306884 LOC102305423 LOC102305423 LOC102292923 LOC102292923 siah1 siah1 rnf40 rnf40 LOC102311320 LOC102311320 rnf41 rnf41 LOC102301389 LOC102301389 LOC102289137 LOC102289137 rnf13 rnf13 LOC102298783 LOC102298783 uba1 uba1 LOC102311528 LOC102311528 gnb1l gnb1l ube2v2 ube2v2 LOC102312912 LOC102312912 LOC102312282 LOC102312282 LOC102314329 LOC102314329 rnf20 rnf20 LOC102306994 LOC102306994 LOC102304081 LOC102304081 usp8 usp8 otub1 otub1 uba2 uba2 sumo1 sumo1 ENSHBUP00000009121 ENSHBUP00000009121 LOC102308555 LOC102308555 LOC102311405 LOC102311405 herc4 herc4 LOC102296415 LOC102296415 LOC102298737 LOC102298737 ENSHBUP00000011337 ENSHBUP00000011337 shprh shprh arih1 arih1 ENSHBUP00000012005 ENSHBUP00000012005 LOC102292864 LOC102292864 hltf hltf LOC102299037 LOC102299037 LOC102312366 LOC102312366 zmiz2 zmiz2 LOC102292082 LOC102292082 rnf128 rnf128 LOC102289514 LOC102289514 traf7 traf7 LOC102294941 LOC102294941 birc6 birc6 ube2g1 ube2g1 ube2a ube2a senp5 senp5 pias1 pias1 LOC102310819 LOC102310819 rnf8 rnf8 ube2z ube2z ube2w ube2w LOC102301675 LOC102301675 ube2b ube2b LOC102310419 LOC102310419 ube2r2 ube2r2 ubb ubb rnf169 rnf169 OTUB2 OTUB2 ube2ql1 ube2ql1 LOC102292652 LOC102292652 LOC102292322 LOC102292322 ube2j2 ube2j2 LOC102311422 LOC102311422 ENSHBUP00000021858 ENSHBUP00000021858 rlim rlim sae1 sae1 ENSHBUP00000022412 ENSHBUP00000022412 cacybp cacybp SUMO3 SUMO3 LOC102305117 LOC102305117 kctd2 kctd2 ube2i ube2i pias4 pias4 ENSHBUP00000024614 ENSHBUP00000024614 LOC102312440 LOC102312440 c1qtnf12 c1qtnf12 senp7 senp7 LOC102309726 LOC102309726 ube2h ube2h rnf168 rnf168 LOC102290748 LOC102290748 LOC102293015 LOC102293015 sumo2 sumo2 LOC102312804 LOC102312804 LOC102296709 LOC102296709 LOC102288495 LOC102288495 rad18 rad18 LOC102313308 LOC102313308 LOC102311858 LOC102311858 STUB1 STUB1 rnf217 rnf217 UBE2D1 UBE2D1 LOC102314666 LOC102314666 rnf4 rnf4 top2b top2b ENSHBUP00000032010 ENSHBUP00000032010 LOC102304546 LOC102304546 cyhr1 cyhr1 tdp1 tdp1 LOC102298013 LOC102298013 LOC102290101 LOC102290101 LOC102305137 LOC102305137 ube2l3 ube2l3 LOC106632864 LOC106632864 LOC102305155 LOC102305155
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ube2j1Ubiquitin-conjugating enzyme E2, J1. (317 aa)
LOC102310624Si:ch211-212o1.2. (283 aa)
LOC102313398Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC102290203Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1012 aa)
LOC102299096Ubiquitin-conjugating enzyme E2Q family member 1. (408 aa)
uba6Ubiquitin like modifier activating enzyme 6. (1052 aa)
LOC102305568DNA-binding protein SATB. (847 aa)
ube2kUbiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
LOC102297909Ubiquitin-conjugating enzyme E2Q family member 2. (377 aa)
ubox5U-box domain containing 5. (677 aa)
LOC102306884Ring finger protein 38. (745 aa)
LOC102305423UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
LOC102292923DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1582 aa)
siah1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (298 aa)
rnf40E3 ubiquitin protein ligase. (1000 aa)
LOC102311320Si:dkey-21c19.3. (728 aa)
rnf41Ring finger protein 41. (318 aa)
LOC102301389DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (566 aa)
LOC102289137Ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (175 aa)
rnf13Ring finger protein 13. (381 aa)
LOC102298783RING-type domain-containing protein. (391 aa)
uba1Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1064 aa)
LOC102311528Ubiquitin specific peptidase 21; Belongs to the peptidase C19 family. (373 aa)
gnb1lGuanine nucleotide binding protein (G protein), beta polypeptide 1-like. (328 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
LOC102312912UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
LOC102312282Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
LOC102314329Ubiquitin carboxyl-terminal hydrolase. (574 aa)
rnf20E3 ubiquitin protein ligase. (1027 aa)
LOC102306994Cell division cycle 34 homolog (S. cerevisiae) a; Belongs to the ubiquitin-conjugating enzyme family. (243 aa)
LOC102304081UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
usp8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1036 aa)
otub1Ubiquitin thioesterase. (279 aa)
uba2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (678 aa)
sumo1Small ubiquitin like modifier 1. (129 aa)
ENSHBUP00000009121Topoisomerase I binding, arginine/serine-rich a. (722 aa)
LOC102308555UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC102311405Uncharacterized protein. (873 aa)
herc4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1067 aa)
LOC102296415Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
LOC102298737E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (332 aa)
ENSHBUP00000011337DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (614 aa)
shprhSNF2 histone linker PHD RING helicase. (1661 aa)
arih1RBR-type E3 ubiquitin transferase. (572 aa)
ENSHBUP00000012005Uncharacterized protein. (75 aa)
LOC102292864Si:ch211-51h9.6. (100 aa)
hltfHelicase-like transcription factor. (968 aa)
LOC102299037UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LOC102312366HECT domain-containing protein. (1026 aa)
zmiz2SP-RING-type domain-containing protein. (887 aa)
LOC102292082Protein inhibitor of activated STAT, 1a. (710 aa)
rnf128RING-type domain-containing protein. (361 aa)
LOC102289514UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (182 aa)
traf7TNF receptor-associated factor 7. (640 aa)
LOC102294941Small ubiquitin-related modifier. (96 aa)
birc6Baculoviral IAP repeat containing 6. (4913 aa)
ube2g1Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
ube2aUbiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
senp5ULP_PROTEASE domain-containing protein. (245 aa)
pias1Protein inhibitor of activated STAT, 1b. (663 aa)
LOC102310819Zinc finger MIZ-type containing 1. (1104 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (464 aa)
ube2zUbiquitin-conjugating enzyme E2Z. (403 aa)
ube2wUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the SKP1 family. (241 aa)
LOC102301675SP-RING-type domain-containing protein. (1102 aa)
ube2bUbiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC102310419UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
ube2r2Ubiquitin-conjugating enzyme E2R 2; Belongs to the ubiquitin-conjugating enzyme family. (260 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
rnf169Ring finger protein 169. (585 aa)
OTUB2OTU deubiquitinase, ubiquitin aldehyde binding 2. (251 aa)
ube2ql1Ubiquitin-conjugating enzyme E2Q family-like 1. (295 aa)
LOC102292652Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC102292322ULP_PROTEASE domain-containing protein. (783 aa)
ube2j2Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast). (261 aa)
LOC102311422UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (169 aa)
ENSHBUP00000021858SUMO specific peptidase 6a. (579 aa)
rlimRing finger protein, LIM domain interacting. (700 aa)
sae1SUMO1 activating enzyme subunit 1. (345 aa)
ENSHBUP00000022412Uncharacterized protein. (1159 aa)
cacybpCalcyclin binding protein. (227 aa)
SUMO3Small ubiquitin-related modifier. (94 aa)
LOC102305117UBIQUITIN_CONJUGAT_2 domain-containing protein. (200 aa)
kctd2Potassium channel tetramerization domain containing 2. (272 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
pias4Protein inhibitor of activated STAT, 4a. (507 aa)
ENSHBUP00000024614SUMO specific peptidase 2. (253 aa)
LOC102312440Small ubiquitin-related modifier. (94 aa)
c1qtnf12C1q and TNF related 12. (320 aa)
senp7SUMO specific peptidase 7. (1039 aa)
LOC102309726Si:dkey-222f2.1; Belongs to the intermediate filament family. (451 aa)
ube2hUbiquitin-conjugating enzyme E2H (UBC8 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
rnf168Ring finger protein 168. (419 aa)
LOC102290748Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
LOC102293015Uncharacterized protein. (1069 aa)
sumo2Ubiquitin-like domain-containing protein. (143 aa)
LOC102312804Ubiquitin-conjugating enzyme E2D 4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC102296709Transmembrane protein 189. (275 aa)
LOC102288495Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (270 aa)
rad18RAD18 E3 ubiquitin protein ligase. (453 aa)
LOC102313308DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (750 aa)
LOC102311858Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
STUB1STIP1 homology and U-box containing protein 1. (290 aa)
rnf217RBR-type E3 ubiquitin transferase. (570 aa)
UBE2D1Ubiquitin-conjugating enzyme E2D 1a; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
rnf4RING-type domain-containing protein. (173 aa)
top2bDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1485 aa)
ENSHBUP00000032010UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (80 aa)
LOC102304546Ubiquitin-conjugating enzyme E2D 3; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
cyhr1Cysteine/histidine-rich 1. (378 aa)
tdp1Tyrosyl-DNA phosphodiesterase 1. (616 aa)
LOC102298013Si:dkey-51a16.9. (154 aa)
LOC102290101Ubiquitin-conjugating enzyme E2D 1b; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC102305137Protein inhibitor of activated STAT, 2. (575 aa)
ube2l3Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC106632864Ubiquitin-like domain-containing protein. (96 aa)
LOC102305155SP-RING-type domain-containing protein. (624 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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