STRINGSTRING
LOC102291388 LOC102291388 LOC102296557 LOC102296557 LOC102303940 LOC102303940 ENSHBUP00000005111 ENSHBUP00000005111 LOC102305908 LOC102305908 fgf23 fgf23 fgfr2 fgfr2 fgf7 fgf7 fgf3 fgf3 fgf4 fgf4 fgf19 fgf19 LOC102307281 LOC102307281 LOC102291075 LOC102291075 LOC102310436 LOC102310436 LOC102304742 LOC102304742 fgf5 fgf5 fgf18 fgf18 fgf22 fgf22 LOC102291452 LOC102291452 LOC102289294 LOC102289294 LOC102304610 LOC102304610 fgf20 fgf20 ENSHBUP00000032881 ENSHBUP00000032881 fgfr4 fgfr4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102291388Uncharacterized protein. (613 aa)
LOC102296557Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
LOC102303940Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
ENSHBUP00000005111Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
LOC102305908Protein kinase domain-containing protein. (466 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)
fgfr2Fibroblast growth factor receptor. (835 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC102307281Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
LOC102291075Fibroblast growth factor receptor. (709 aa)
LOC102310436Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC102304742Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
LOC102291452Fibroblast growth factor receptor. (818 aa)
LOC102289294Fibroblast growth factor receptor. (836 aa)
LOC102304610Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
ENSHBUP00000032881Fibroblast growth factor binding protein 1b. (219 aa)
fgfr4Fibroblast growth factor receptor 4. (945 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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