(6 nodes) Phospholipase C-beta, conserved site, and G-protein alpha subunit, group Q network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102308147	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4. (369 aa)
	plcb3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1262 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1257 aa)
	LOC102306178	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
	LOC102311416	Uncharacterized protein. (359 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1268 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102306178	LOC102308147	ENSHBUP00000025997	ENSHBUP00000007087	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	0.796
LOC102306178	LOC102311416	ENSHBUP00000025997	ENSHBUP00000026340	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Uncharacterized protein.	0.829
LOC102306178	PLCB2	ENSHBUP00000025997	ENSHBUP00000030637	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.915
LOC102306178	PLCB4	ENSHBUP00000025997	ENSHBUP00000015133	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.918
LOC102306178	plcb3	ENSHBUP00000025997	ENSHBUP00000014971	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.916
LOC102308147	LOC102306178	ENSHBUP00000007087	ENSHBUP00000025997	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	0.796
LOC102308147	LOC102311416	ENSHBUP00000007087	ENSHBUP00000026340	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Uncharacterized protein.	0.826
LOC102308147	PLCB2	ENSHBUP00000007087	ENSHBUP00000030637	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.913
LOC102308147	PLCB4	ENSHBUP00000007087	ENSHBUP00000015133	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.913
LOC102308147	plcb3	ENSHBUP00000007087	ENSHBUP00000014971	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.913
LOC102311416	LOC102306178	ENSHBUP00000026340	ENSHBUP00000025997	Uncharacterized protein.	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	0.829
LOC102311416	LOC102308147	ENSHBUP00000026340	ENSHBUP00000007087	Uncharacterized protein.	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	0.826
LOC102311416	PLCB2	ENSHBUP00000026340	ENSHBUP00000030637	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.927
LOC102311416	PLCB4	ENSHBUP00000026340	ENSHBUP00000015133	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.937
LOC102311416	plcb3	ENSHBUP00000026340	ENSHBUP00000014971	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.927
PLCB2	LOC102306178	ENSHBUP00000030637	ENSHBUP00000025997	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	0.915
PLCB2	LOC102308147	ENSHBUP00000030637	ENSHBUP00000007087	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	0.913
PLCB2	LOC102311416	ENSHBUP00000030637	ENSHBUP00000026340	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Uncharacterized protein.	0.927
PLCB2	PLCB4	ENSHBUP00000030637	ENSHBUP00000015133	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.854
PLCB2	plcb3	ENSHBUP00000030637	ENSHBUP00000014971	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.856