(11 nodes) Retromer complex network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vps26b	VPS26, retromer complex component B. (333 aa)
	snx17	Sorting nexin 17. (466 aa)
	snx3	Sorting nexin 3. (157 aa)
	tbc1d5	TBC1 domain family, member 5. (747 aa)
	LOC102306411	Sorting nexin 27a. (563 aa)
	vps29	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (225 aa)
	LOC102302839	Sorting nexin 12. (172 aa)
	SNX27	Sorting nexin 27. (571 aa)
	vps35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (798 aa)
	vps26a	VPS26, retromer complex component A. (328 aa)
	LOC102297476	Uncharacterized protein. (365 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102297476	LOC102302839	ENSHBUP00000032224	ENSHBUP00000022935	Uncharacterized protein.	Sorting nexin 12.	0.953
LOC102297476	LOC102306411	ENSHBUP00000032224	ENSHBUP00000018504	Uncharacterized protein.	Sorting nexin 27a.	0.754
LOC102297476	SNX27	ENSHBUP00000032224	ENSHBUP00000023227	Uncharacterized protein.	Sorting nexin 27.	0.754
LOC102297476	snx17	ENSHBUP00000032224	ENSHBUP00000011136	Uncharacterized protein.	Sorting nexin 17.	0.695
LOC102297476	snx3	ENSHBUP00000032224	ENSHBUP00000011821	Uncharacterized protein.	Sorting nexin 3.	0.953
LOC102297476	tbc1d5	ENSHBUP00000032224	ENSHBUP00000015585	Uncharacterized protein.	TBC1 domain family, member 5.	0.898
LOC102297476	vps26a	ENSHBUP00000032224	ENSHBUP00000031807	Uncharacterized protein.	VPS26, retromer complex component A.	0.968
LOC102297476	vps26b	ENSHBUP00000032224	ENSHBUP00000002641	Uncharacterized protein.	VPS26, retromer complex component B.	0.829
LOC102297476	vps29	ENSHBUP00000032224	ENSHBUP00000021114	Uncharacterized protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.978
LOC102297476	vps35	ENSHBUP00000032224	ENSHBUP00000028561	Uncharacterized protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.990
LOC102302839	LOC102297476	ENSHBUP00000022935	ENSHBUP00000032224	Sorting nexin 12.	Uncharacterized protein.	0.953
LOC102302839	LOC102306411	ENSHBUP00000022935	ENSHBUP00000018504	Sorting nexin 12.	Sorting nexin 27a.	0.492
LOC102302839	SNX27	ENSHBUP00000022935	ENSHBUP00000023227	Sorting nexin 12.	Sorting nexin 27.	0.492
LOC102302839	snx17	ENSHBUP00000022935	ENSHBUP00000011136	Sorting nexin 12.	Sorting nexin 17.	0.527
LOC102302839	snx3	ENSHBUP00000022935	ENSHBUP00000011821	Sorting nexin 12.	Sorting nexin 3.	0.853
LOC102302839	tbc1d5	ENSHBUP00000022935	ENSHBUP00000015585	Sorting nexin 12.	TBC1 domain family, member 5.	0.518
LOC102302839	vps26a	ENSHBUP00000022935	ENSHBUP00000031807	Sorting nexin 12.	VPS26, retromer complex component A.	0.958
LOC102302839	vps26b	ENSHBUP00000022935	ENSHBUP00000002641	Sorting nexin 12.	VPS26, retromer complex component B.	0.953
LOC102302839	vps29	ENSHBUP00000022935	ENSHBUP00000021114	Sorting nexin 12.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.886
LOC102302839	vps35	ENSHBUP00000022935	ENSHBUP00000028561	Sorting nexin 12.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.982