(32 nodes) Mixed, incl. cDENN domain, and Organic solute carrier protein 1 network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rab35	RAB35, member RAS oncogene family b. (201 aa)
	LOC102291680	Organic solute carrier partner 1a. (364 aa)
	ENSHBUP00000002760	Uncharacterized protein. (495 aa)
	ENSHBUP00000003187	UDENN domain-containing protein. (309 aa)
	ENSHBUP00000003194	Uncharacterized protein. (126 aa)
	LOC102300433	DENN/MADD domain containing 5B. (1266 aa)
	wdr54	WD repeat domain 54. (336 aa)
	LOC102292541	Uncharacterized protein. (1103 aa)
	evi5	Ecotropic viral integration site 5b. (832 aa)
	TBC1D13	TBC1 domain family member 13. (400 aa)
	LOC102311995	Uncharacterized protein. (1165 aa)
	dennd4a	DENN/MADD domain containing 4A. (1708 aa)
	DENND2A	DENN domain containing 2A. (1055 aa)
	ENSHBUP00000014903	WD_REPEATS_REGION domain-containing protein. (252 aa)
	dennd5a	DENN/MADD domain containing 5A. (1358 aa)
	LOC102293669	Si:dkey-76b14.2. (925 aa)
	dennd1b	DENN/MADD domain containing 1B. (870 aa)
	LOC102293940	Si:dkey-16l2.16. (224 aa)
	dennd2c	DENN/MADD domain containing 2C. (927 aa)
	usp16	Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (844 aa)
	dennd1a	DENN/MADD domain containing 1A. (831 aa)
	rab12	RAB12, member RAS oncogene family. (243 aa)
	dennd4b	DENN/MADD domain containing 4B. (1368 aa)
	OSCP1	Organic solute carrier partner 1. (380 aa)
	dennd2d	DENN/MADD domain containing 2Da. (571 aa)
	DENND4A	DENN domain containing 4A. (2013 aa)
	dennd2b	Suppression of tumorigenicity 5. (1134 aa)
	ENSHBUP00000031216	UDENN domain-containing protein. (199 aa)
	tbc1d24	TBC1 domain family, member 24. (571 aa)
	ENSHBUP00000032696	Uncharacterized protein. (400 aa)
	LOC102293117	TBC1 domain family, member 10Ab. (475 aa)
	LOC102310746	Zgc:65873. (220 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENND2A	LOC102293940	ENSHBUP00000013418	ENSHBUP00000017243	DENN domain containing 2A.	Si:dkey-16l2.16.	0.779
DENND2A	rab35	ENSHBUP00000013418	ENSHBUP00000000258	DENN domain containing 2A.	RAB35, member RAS oncogene family b.	0.779
DENND4A	rab12	ENSHBUP00000030761	ENSHBUP00000026068	DENN domain containing 4A.	RAB12, member RAS oncogene family.	0.404
ENSHBUP00000002760	LOC102293940	ENSHBUP00000002760	ENSHBUP00000017243	Uncharacterized protein.	Si:dkey-16l2.16.	0.719
ENSHBUP00000002760	TBC1D13	ENSHBUP00000002760	ENSHBUP00000011163	Uncharacterized protein.	TBC1 domain family member 13.	0.424
ENSHBUP00000002760	rab35	ENSHBUP00000002760	ENSHBUP00000000258	Uncharacterized protein.	RAB35, member RAS oncogene family b.	0.719
ENSHBUP00000003187	LOC102293940	ENSHBUP00000003187	ENSHBUP00000017243	UDENN domain-containing protein.	Si:dkey-16l2.16.	0.779
ENSHBUP00000003187	rab35	ENSHBUP00000003187	ENSHBUP00000000258	UDENN domain-containing protein.	RAB35, member RAS oncogene family b.	0.779
ENSHBUP00000003194	LOC102293940	ENSHBUP00000003194	ENSHBUP00000017243	Uncharacterized protein.	Si:dkey-16l2.16.	0.779
ENSHBUP00000003194	rab35	ENSHBUP00000003194	ENSHBUP00000000258	Uncharacterized protein.	RAB35, member RAS oncogene family b.	0.779
ENSHBUP00000014903	ENSHBUP00000031216	ENSHBUP00000014903	ENSHBUP00000031216	WD_REPEATS_REGION domain-containing protein.	UDENN domain-containing protein.	0.831
ENSHBUP00000014903	rab12	ENSHBUP00000014903	ENSHBUP00000026068	WD_REPEATS_REGION domain-containing protein.	RAB12, member RAS oncogene family.	0.777
ENSHBUP00000031216	ENSHBUP00000014903	ENSHBUP00000031216	ENSHBUP00000014903	UDENN domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.831
ENSHBUP00000031216	rab12	ENSHBUP00000031216	ENSHBUP00000026068	UDENN domain-containing protein.	RAB12, member RAS oncogene family.	0.777
ENSHBUP00000032696	rab12	ENSHBUP00000032696	ENSHBUP00000026068	Uncharacterized protein.	RAB12, member RAS oncogene family.	0.404
LOC102291680	wdr54	ENSHBUP00000000536	ENSHBUP00000008509	Organic solute carrier partner 1a.	WD repeat domain 54.	0.627
LOC102292541	dennd1a	ENSHBUP00000009328	ENSHBUP00000024746	Uncharacterized protein.	DENN/MADD domain containing 1A.	0.405
LOC102293117	LOC102293940	ENSHBUP00000033836	ENSHBUP00000017243	TBC1 domain family, member 10Ab.	Si:dkey-16l2.16.	0.771
LOC102293117	TBC1D13	ENSHBUP00000033836	ENSHBUP00000011163	TBC1 domain family, member 10Ab.	TBC1 domain family member 13.	0.403
LOC102293117	rab35	ENSHBUP00000033836	ENSHBUP00000000258	TBC1 domain family, member 10Ab.	RAB35, member RAS oncogene family b.	0.771