(20 nodes) Ino80 complex, and DNA translocase activity network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102298468	Uncharacterized protein. (474 aa)
	LOC102296485	Si:ch73-290k24.6. (845 aa)
	actr8	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (643 aa)
	rad54l	RAD54 like. (739 aa)
	ino80b	INO80 complex subunit B. (342 aa)
	wbp1	Uncharacterized protein. (529 aa)
	actr5	Actin related protein 5; Belongs to the actin family. (624 aa)
	rad54b	RAD54 homolog B. (935 aa)
	ino80c	INO80 complex subunit C. (203 aa)
	ruvbl2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (478 aa)
	ino80	INO80 complex ATPase subunit. (1497 aa)
	shroom4	ASD2 domain-containing protein. (1718 aa)
	mcrs1	Microspherule protein 1. (466 aa)
	ercc6l2	Excision repair cross-complementation group 6-like 2. (1535 aa)
	nfrkb	Nuclear factor related to kappaB binding protein. (1274 aa)
	tfpt	TCF3 (E2A) fusion partner. (199 aa)
	LOC102305356	Actin, alpha cardiac. (377 aa)
	ruvbl1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (462 aa)
	ENSHBUP00000028273	Uncharacterized protein. (107 aa)
	ino80e	INO80 complex subunit E. (236 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000028273	LOC102296485	ENSHBUP00000028273	ENSHBUP00000000894	Uncharacterized protein.	Si:ch73-290k24.6.	0.429
ENSHBUP00000028273	LOC102298468	ENSHBUP00000028273	ENSHBUP00000000130	Uncharacterized protein.	Uncharacterized protein.	0.466
ENSHBUP00000028273	LOC102305356	ENSHBUP00000028273	ENSHBUP00000025003	Uncharacterized protein.	Actin, alpha cardiac.	0.480
ENSHBUP00000028273	actr5	ENSHBUP00000028273	ENSHBUP00000009502	Uncharacterized protein.	Actin related protein 5; Belongs to the actin family.	0.781
ENSHBUP00000028273	actr8	ENSHBUP00000028273	ENSHBUP00000003800	Uncharacterized protein.	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	0.470
ENSHBUP00000028273	ercc6l2	ENSHBUP00000028273	ENSHBUP00000023552	Uncharacterized protein.	Excision repair cross-complementation group 6-like 2.	0.729
ENSHBUP00000028273	ino80	ENSHBUP00000028273	ENSHBUP00000020298	Uncharacterized protein.	INO80 complex ATPase subunit.	0.697
ENSHBUP00000028273	ino80b	ENSHBUP00000028273	ENSHBUP00000008451	Uncharacterized protein.	INO80 complex subunit B.	0.429
ENSHBUP00000028273	ino80c	ENSHBUP00000028273	ENSHBUP00000014760	Uncharacterized protein.	INO80 complex subunit C.	0.741
ENSHBUP00000028273	mcrs1	ENSHBUP00000028273	ENSHBUP00000023540	Uncharacterized protein.	Microspherule protein 1.	0.641
ENSHBUP00000028273	nfrkb	ENSHBUP00000028273	ENSHBUP00000023788	Uncharacterized protein.	Nuclear factor related to kappaB binding protein.	0.635
ENSHBUP00000028273	ruvbl1	ENSHBUP00000028273	ENSHBUP00000026282	Uncharacterized protein.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.777
ENSHBUP00000028273	ruvbl2	ENSHBUP00000028273	ENSHBUP00000014846	Uncharacterized protein.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.711
ENSHBUP00000028273	shroom4	ENSHBUP00000028273	ENSHBUP00000020538	Uncharacterized protein.	ASD2 domain-containing protein.	0.466
ENSHBUP00000028273	tfpt	ENSHBUP00000028273	ENSHBUP00000024088	Uncharacterized protein.	TCF3 (E2A) fusion partner.	0.466
ENSHBUP00000028273	wbp1	ENSHBUP00000028273	ENSHBUP00000009047	Uncharacterized protein.	Uncharacterized protein.	0.429
LOC102296485	ENSHBUP00000028273	ENSHBUP00000000894	ENSHBUP00000028273	Si:ch73-290k24.6.	Uncharacterized protein.	0.429
LOC102296485	LOC102298468	ENSHBUP00000000894	ENSHBUP00000000130	Si:ch73-290k24.6.	Uncharacterized protein.	0.403
LOC102296485	LOC102305356	ENSHBUP00000000894	ENSHBUP00000025003	Si:ch73-290k24.6.	Actin, alpha cardiac.	0.608
LOC102296485	actr5	ENSHBUP00000000894	ENSHBUP00000009502	Si:ch73-290k24.6.	Actin related protein 5; Belongs to the actin family.	0.958