52 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mixl1	Mix paired-like homeobox. (284 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	sbds	SBDS ribosome maturation factor. (249 aa)
	LOC102301961	T-cell acute lymphocytic leukemia 1. (385 aa)
	LOC102314283	Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
	sh2b3	SH2B adaptor protein 3. (723 aa)
	LOC102294502	Uncharacterized protein. (772 aa)
	LOC102290494	Zgc:103499. (319 aa)
	meox1	Mesenchyme homeobox 1. (275 aa)
	lig4	DNA ligase. (910 aa)
	pkd2	Polycystic kidney disease 2. (902 aa)
	LOC102289249	Notch receptor 1a. (2455 aa)
	LOC102300958	Solute carrier family 37 member 4b. (450 aa)
	GATA2	GATA binding protein 2. (455 aa)
	fsd1	Fibronectin type III and SPRY domain containing 1. (493 aa)
	fstl3	Follistatin-like 3 (secreted glycoprotein). (250 aa)
	zfat	Zinc finger and AT hook domain containing. (1234 aa)
	notch1	Notch receptor 1b. (2411 aa)
	ENSHBUP00000012083	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1302 aa)
	kdr	Kinase insert domain receptor (a type III receptor tyrosine kinase). (1356 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (412 aa)
	ENSHBUP00000013968	VWFC domain-containing protein. (232 aa)
	tnfrsf13b	TACI-CRD2 domain-containing protein. (247 aa)
	mlf1	Myeloid leukemia factor 1. (267 aa)
	fev	FEV transcription factor, ETS family member. (220 aa)
	flt1	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1277 aa)
	ENSHBUP00000016877	Uncharacterized protein. (126 aa)
	SP3	Sp3a transcription factor. (671 aa)
	plek	Pleckstrin. (351 aa)
	ufl1	UFM1-specific ligase 1. (754 aa)
	agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon). (365 aa)
	xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5. (739 aa)
	pdgfrb	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1104 aa)
	LOC102310037	WD repeat domain 78. (797 aa)
	adar	Adenosine deaminase RNA specific. (1360 aa)
	slc37a4	Solute carrier family 37 member 4a. (426 aa)
	LOC102291044	Sp3b transcription factor. (600 aa)
	cebpd	CCAAT/enhancer-binding protein. (265 aa)
	g6pc3	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (339 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (1019 aa)
	rspo1	R-spondin 1. (276 aa)
	SRF	Serum response factor. (597 aa)
	LOC102311635	GATA binding protein 2a. (465 aa)
	flt4	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1395 aa)
	batf	Basic leucine zipper transcription factor, ATF-like. (123 aa)
	ENSHBUP00000028833	BHLH domain-containing protein. (97 aa)
	bves	Blood vessel epicardial substance. (348 aa)
	LOC102295114	MADS-box domain-containing protein. (503 aa)
	ptprz1	Protein tyrosine phosphatase receptor type Z1b. (1271 aa)
	ptprq	Protein tyrosine phosphatase receptor type Q. (2113 aa)
	setd1b	SET domain containing 1B, histone lysine methyltransferase a. (1807 aa)
	ARMC6	Armadillo repeat containing 6. (465 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000012083	LOC102294502	ENSHBUP00000012083	ENSHBUP00000003227	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Uncharacterized protein.	0.471
ENSHBUP00000012083	pdgfrb	ENSHBUP00000012083	ENSHBUP00000022724	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.795
ENSHBUP00000028833	GATA2	ENSHBUP00000028833	ENSHBUP00000007445	BHLH domain-containing protein.	GATA binding protein 2.	0.787
ENSHBUP00000028833	LOC102311635	ENSHBUP00000028833	ENSHBUP00000027533	BHLH domain-containing protein.	GATA binding protein 2a.	0.787
GATA2	ENSHBUP00000028833	ENSHBUP00000007445	ENSHBUP00000028833	GATA binding protein 2.	BHLH domain-containing protein.	0.787
GATA2	LOC102295114	ENSHBUP00000007445	ENSHBUP00000030051	GATA binding protein 2.	MADS-box domain-containing protein.	0.718
GATA2	LOC102301961	ENSHBUP00000007445	ENSHBUP00000001586	GATA binding protein 2.	T-cell acute lymphocytic leukemia 1.	0.787
GATA2	SRF	ENSHBUP00000007445	ENSHBUP00000027140	GATA binding protein 2.	Serum response factor.	0.718
GATA2	batf	ENSHBUP00000007445	ENSHBUP00000028621	GATA binding protein 2.	Basic leucine zipper transcription factor, ATF-like.	0.428
GATA2	setd1b	ENSHBUP00000007445	ENSHBUP00000033212	GATA binding protein 2.	SET domain containing 1B, histone lysine methyltransferase a.	0.593
LOC102289249	LOC102294502	ENSHBUP00000006095	ENSHBUP00000003227	Notch receptor 1a.	Uncharacterized protein.	0.425
LOC102289249	LOC102314283	ENSHBUP00000006095	ENSHBUP00000001653	Notch receptor 1a.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.422
LOC102289249	myc	ENSHBUP00000006095	ENSHBUP00000013794	Notch receptor 1a.	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.434
LOC102291044	myc	ENSHBUP00000024547	ENSHBUP00000013794	Sp3b transcription factor.	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.424
LOC102294502	ENSHBUP00000012083	ENSHBUP00000003227	ENSHBUP00000012083	Uncharacterized protein.	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.471
LOC102294502	LOC102289249	ENSHBUP00000003227	ENSHBUP00000006095	Uncharacterized protein.	Notch receptor 1a.	0.425
LOC102294502	flt1	ENSHBUP00000003227	ENSHBUP00000016500	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.466
LOC102294502	flt4	ENSHBUP00000003227	ENSHBUP00000027706	Uncharacterized protein.	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.471
LOC102294502	kdr	ENSHBUP00000003227	ENSHBUP00000013371	Uncharacterized protein.	Kinase insert domain receptor (a type III receptor tyrosine kinase).	0.471
LOC102294502	notch1	ENSHBUP00000003227	ENSHBUP00000010438	Uncharacterized protein.	Notch receptor 1b.	0.425