STRINGSTRING
LOC102302702 LOC102302702 pcid2 pcid2 alyref alyref ENSHBUP00000000398 ENSHBUP00000000398 LOC102310315 LOC102310315 kpna4 kpna4 nmd3 nmd3 ENSHBUP00000000803 ENSHBUP00000000803 ENSHBUP00000001166 ENSHBUP00000001166 atxn1 atxn1 LOC102314283 LOC102314283 nup153 nup153 SRSF3 SRSF3 LOC102300404 LOC102300404 LOC102301397 LOC102301397 ddx39a ddx39a xpo4 xpo4 ENSHBUP00000002785 ENSHBUP00000002785 thoc7 thoc7 nup107 nup107 ENSHBUP00000004062 ENSHBUP00000004062 ENSHBUP00000004110 ENSHBUP00000004110 ENSHBUP00000004145 ENSHBUP00000004145 tpr tpr lsg1 lsg1 NUP54 NUP54 ssb ssb ndc1 ndc1 ltv1 ltv1 snupn snupn ankle1 ankle1 LOC102297700 LOC102297700 LOC102308778 LOC102308778 nup160 nup160 LOC102306071 LOC102306071 LOC102294572 LOC102294572 txnip txnip tnpo1 tnpo1 tmco6 tmco6 cdk5 cdk5 ENSHBUP00000007056 ENSHBUP00000007056 htatip2 htatip2 strada strada ENSHBUP00000007219 ENSHBUP00000007219 ipo9 ipo9 LOC102303514 LOC102303514 thoc1 thoc1 eif6 eif6 nup88 nup88 nol6 nol6 abce1 abce1 gle1 gle1 LOC102302540 LOC102302540 nup85 nup85 rae1 rae1 pola2 pola2 ENSHBUP00000010540 ENSHBUP00000010540 nup93 nup93 nxf1 nxf1 LOC102293927 LOC102293927 adgrd1 adgrd1 KPNA2 KPNA2 LOC102301124 LOC102301124 LOC102293011 LOC102293011 gckr gckr anp32a anp32a med1 med1 ipo5 ipo5 appl2 appl2 LOC102300610 LOC102300610 STRADB STRADB nup42 nup42 nfkbia nfkbia nup205 nup205 kpnb1 kpnb1 kpna1 kpna1 phax phax FAM53B FAM53B LOC102291565 LOC102291565 ipo7 ipo7 polr2d polr2d fyttd1 fyttd1 ENSHBUP00000015737 ENSHBUP00000015737 sqstm1 sqstm1 ENSHBUP00000016048 ENSHBUP00000016048 ENSHBUP00000016099 ENSHBUP00000016099 tsc2 tsc2 rsrc1 rsrc1 LOC102300697 LOC102300697 alkbh5 alkbh5 LOC102296374 LOC102296374 ENSHBUP00000016877 ENSHBUP00000016877 NUP62 NUP62 ENSHBUP00000017041 ENSHBUP00000017041 LOC102303322 LOC102303322 ythdc1 ythdc1 pom121 pom121 LOC102296327 LOC102296327 LOC102310120 LOC102310120 LOC102296990 LOC102296990 DDX39A DDX39A NCBP1 NCBP1 heatr3 heatr3 nup155 nup155 LOC102305279 LOC102305279 traf3ip2 traf3ip2 LOC102293583 LOC102293583 xpo5 xpo5 ing1 ing1 LOC102305488 LOC102305488 LOC102313071 LOC102313071 LOC102291934 LOC102291934 appl1 appl1 xpo7 xpo7 ENSHBUP00000022138 ENSHBUP00000022138 LOC102289472 LOC102289472 FAM53C FAM53C ranbp2 ranbp2 nxt2 nxt2 nf1 nf1 LOC102305872 LOC102305872 lzts3 lzts3 thoc2 thoc2 nop9 nop9 ncbp2 ncbp2 ipo11 ipo11 sec13 sec13 sdad1 sdad1 gpn3 gpn3 kpna3 kpna3 nup133 nup133 LOC102313919 LOC102313919 lzts2 lzts2 LOC102307454 LOC102307454 xpo1 xpo1 chtop chtop LOC102311788 LOC102311788 nup188 nup188 smo smo tnpo3 tnpo3 ENSHBUP00000026119 ENSHBUP00000026119 ranbp1 ranbp1 NEMF NEMF sarnp sarnp aaas aaas rpain rpain LOC102307684 LOC102307684 thoc5 thoc5 nutf2 nutf2 nup43 nup43 ran ran kpna5 kpna5 ipo8 ipo8 cited1 cited1 hspa9 hspa9 LOC102313910 LOC102313910 thoc6 thoc6 chp1 chp1 ctdspl2 ctdspl2 LOC102299188 LOC102299188 tnpo2 tnpo2 lrrk2 lrrk2 LOC102293118 LOC102293118 rangap1 rangap1 pkd1 pkd1 LOC102309785 LOC102309785 sem1 sem1 ppp3r1 ppp3r1 nup214 nup214 fam53b fam53b xpo6 xpo6 spg11 spg11 LOC102308132 LOC102308132 nup50 nup50 gpn2 gpn2 xpot xpot ankrd54 ankrd54 poldip3 poldip3 styx styx LOC102312867 LOC102312867 LOC102308632 LOC102308632 mcm3ap mcm3ap LOC102294846 LOC102294846 fbxo22 fbxo22 EIF4ENIF1 EIF4ENIF1 abra abra ipo4 ipo4 desi1 desi1 nup58 nup58 thoc3 thoc3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102302702DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast). (487 aa)
pcid2PCI domain containing 2. (377 aa)
alyrefRRM domain-containing protein. (265 aa)
ENSHBUP00000000398Uncharacterized protein. (265 aa)
LOC102310315Si:ch211-216l23.2. (424 aa)
kpna4Importin subunit alpha; Belongs to the importin alpha family. (520 aa)
nmd360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (504 aa)
ENSHBUP00000000803Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (144 aa)
ENSHBUP00000001166Uncharacterized protein. (102 aa)
atxn1Ataxin 1a. (811 aa)
LOC102314283Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
nup153Nucleoporin 153. (1526 aa)
SRSF3Serine and arginine rich splicing factor 3. (171 aa)
LOC102300404FCP1 homology domain-containing protein. (478 aa)
LOC102301397Uncharacterized protein. (179 aa)
ddx39aUncharacterized protein. (427 aa)
xpo4Exportin 4. (1159 aa)
ENSHBUP00000002785Uncharacterized protein. (243 aa)
thoc7THO complex 7. (203 aa)
nup107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (908 aa)
ENSHBUP00000004062TSC complex subunit 1b. (432 aa)
ENSHBUP00000004110PLAT domain-containing protein. (257 aa)
ENSHBUP00000004145Polycystic kidney disease 1b. (2666 aa)
tprTranslocated promoter region b, nuclear basket protein. (2192 aa)
lsg1Large 60S subunit nuclear export GTPase 1. (640 aa)
NUP54Nucleoporin 54. (621 aa)
ssbSmall RNA binding exonuclease protection factor La. (393 aa)
ndc1NDC1 transmembrane nucleoporin. (663 aa)
ltv1LTV1 ribosome biogenesis factor. (467 aa)
snupnSnurportin 1. (373 aa)
ankle1Uncharacterized protein. (1145 aa)
LOC102297700MALT paracaspase 1. (828 aa)
LOC102308778TRAF3 interacting protein 2-like. (440 aa)
nup160Nucleoporin 160. (1289 aa)
LOC102306071ELAV-like protein; Belongs to the RRM elav family. (359 aa)
LOC102294572AXH domain-containing protein. (675 aa)
txnipThioredoxin interacting protein. (396 aa)
tnpo1Transportin 1. (890 aa)
tmco6Transmembrane and coiled-coil domains 6. (508 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSHBUP00000007056Nucleoporin 37. (313 aa)
htatip2HIV-1 Tat interactive protein 2. (279 aa)
stradaSTE20 related adaptor alpha. (428 aa)
ENSHBUP00000007219Heat shock protein nuclear import factor hikeshi. (140 aa)
ipo9Importin 9. (914 aa)
LOC102303514MALT paracaspase 2. (801 aa)
thoc1THO complex 1. (654 aa)
eif6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (225 aa)
nup88Nucleoporin 88. (719 aa)
nol6Nucleolar protein 6. (1183 aa)
abce1ATP-binding cassette, sub-family E (OABP), member 1. (413 aa)
gle1GLE1 RNA export mediator. (717 aa)
LOC102302540Importin subunit alpha; Belongs to the importin alpha family. (577 aa)
nup85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (540 aa)
rae1Ribonucleic acid export 1. (369 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
ENSHBUP00000010540Si:dkey-29b11.3. (81 aa)
nup93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (820 aa)
nxf1Zgc:153681. (639 aa)
LOC102293927Desumoylating isopeptidase 1a. (168 aa)
adgrd1Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (883 aa)
KPNA2Importin subunit alpha; Belongs to the importin alpha family. (524 aa)
LOC102301124Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (98 aa)
LOC102293011Si:ch73-182a11.2. (957 aa)
gckrUncharacterized protein. (602 aa)
anp32aAcidic (leucine-rich) nuclear phosphoprotein 32 family, member A. (257 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1838 aa)
ipo5Karyopherin (importin) beta 3. (1093 aa)
appl2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (612 aa)
LOC102300610MALT paracaspase 3. (548 aa)
STRADBSTE20 related adaptor beta. (429 aa)
nup42Nucleoporin 42. (488 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
nup205Nucleoporin 205. (1934 aa)
kpnb1Karyopherin (importin) beta 1. (876 aa)
kpna1Importin subunit alpha; Belongs to the importin alpha family. (494 aa)
phaxPhosphorylated adaptor for RNA export. (409 aa)
FAM53BFamily with sequence similarity 53 member B. (435 aa)
LOC102291565Importin subunit alpha; Belongs to the importin alpha family. (529 aa)
ipo7Importin 7. (1039 aa)
polr2dRPOL4c domain-containing protein. (509 aa)
fyttd1Uncharacterized protein. (318 aa)
ENSHBUP00000015737TFIIS N-terminal domain-containing protein. (661 aa)
sqstm1Sequestosome 1. (426 aa)
ENSHBUP00000016048Uncharacterized protein. (505 aa)
ENSHBUP00000016099Peptidase S59 domain-containing protein. (193 aa)
tsc2TSC complex subunit 2. (1741 aa)
rsrc1Arginine/serine-rich coiled-coil 1. (238 aa)
LOC102300697Importin N-terminal domain-containing protein. (889 aa)
alkbh5AlkB homolog 5, RNA demethylase. (357 aa)
LOC102296374Importin 13. (961 aa)
ENSHBUP00000016877Uncharacterized protein. (126 aa)
NUP62Nucleoporin 62. (562 aa)
ENSHBUP00000017041Uncharacterized protein. (177 aa)
LOC102303322Family with sequence similarity 53 member C. (434 aa)
ythdc1YTH domain containing 1. (683 aa)
pom121POM121 transmembrane nucleoporin. (1177 aa)
LOC102296327Translocated promoter region a, nuclear basket protein. (1747 aa)
LOC102310120Nucleophosmin 1b. (313 aa)
LOC102296990Exportin 1 (CRM1 homolog, yeast) b. (1071 aa)
DDX39ADExD-box helicase 39A. (427 aa)
NCBP1Nuclear cap binding protein subunit 1. (795 aa)
heatr3HEAT repeat containing 3. (678 aa)
nup155Nucleoporin 155. (1365 aa)
LOC102305279Importin subunit alpha; Belongs to the importin alpha family. (523 aa)
traf3ip2SEFIR domain-containing protein. (404 aa)
LOC102293583Uncharacterized protein. (270 aa)
xpo5Exportin 5. (1236 aa)
ing1Inhibitor of growth protein. (328 aa)
LOC102305488RRM domain-containing protein. (168 aa)
LOC102313071Nucleophosmin 1a. (315 aa)
LOC102291934Uncharacterized protein. (181 aa)
appl1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (708 aa)
xpo7Exportin 7. (1153 aa)
ENSHBUP00000022138Akirin 2. (139 aa)
LOC102289472DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B. (225 aa)
FAM53CFamily with sequence similarity 53 member C. (402 aa)
ranbp2RAN binding protein 2. (3058 aa)
nxt2Nuclear transport factor 2-like export factor 2. (143 aa)
nf1Neurofibromin 1b. (2772 aa)
LOC102305872Si:dkeyp-20g2.1. (872 aa)
lzts3Leucine zipper, putative tumor suppressor family member 3b. (1037 aa)
thoc2THO complex 2. (1460 aa)
nop9Uncharacterized protein. (613 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (191 aa)
ipo11Importin 11. (975 aa)
sec13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (331 aa)
sdad1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (684 aa)
gpn3GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (285 aa)
kpna3Importin subunit alpha; Belongs to the importin alpha family. (521 aa)
nup133Nucleoporin 133. (1135 aa)
LOC102313919Zgc:193690. (483 aa)
lzts2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (695 aa)
LOC102307454SEFIR domain-containing protein. (437 aa)
xpo1Exportin 1 (CRM1 homolog, yeast) a. (1066 aa)
chtopChromatin target of PRMT1a. (241 aa)
LOC102311788ELAV-like protein; Belongs to the RRM elav family. (348 aa)
nup188Nucleoporin 188. (1632 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (825 aa)
tnpo3Transportin 3. (923 aa)
ENSHBUP00000026119Uncharacterized protein. (78 aa)
ranbp1RAN binding protein 1. (212 aa)
NEMFNuclear export mediator factor. (670 aa)
sarnpSAP domain containing ribonucleoprotein. (210 aa)
aaasAchalasia, adrenocortical insufficiency, alacrimia. (520 aa)
rpainRPA interacting protein. (243 aa)
LOC102307684Arrestin_C domain-containing protein. (397 aa)
thoc5THO complex 5. (690 aa)
nutf2Nuclear transport factor 2. (127 aa)
nup43Nucleoporin 43. (372 aa)
ranGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (243 aa)
kpna5Importin subunit alpha; Belongs to the importin alpha family. (536 aa)
ipo8Importin 8. (1018 aa)
cited1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (153 aa)
hspa9Heat shock protein 9; Belongs to the heat shock protein 70 family. (634 aa)
LOC102313910Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (315 aa)
thoc6THO complex 6. (352 aa)
chp1Calcineurin-like EF-hand protein 1. (195 aa)
ctdspl2CTD small phosphatase like 2. (504 aa)
LOC102299188CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3. (266 aa)
tnpo2Transportin 2 (importin 3, karyopherin beta 2b). (889 aa)
lrrk2Leucine-rich repeat kinase 2. (2426 aa)
LOC102293118Ataxin 1b. (833 aa)
rangap1RAN GTPase activating protein 1a. (552 aa)
pkd1Polycystic kidney disease 1a. (4593 aa)
LOC102309785Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (96 aa)
sem1SEM1 26S proteasome complex subunit. (70 aa)
ppp3r1Uncharacterized protein. (174 aa)
nup214Uncharacterized protein. (1830 aa)
fam53bFamily with sequence similarity 53 member B. (419 aa)
xpo6Exportin 6. (1152 aa)
spg11SPG11 vesicle trafficking associated, spatacsin. (2048 aa)
LOC102308132Aly/REF export factor. (273 aa)
nup50Nucleoporin 50. (469 aa)
gpn2GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (313 aa)
xpotExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (998 aa)
ankrd54Ankyrin repeat domain 54. (319 aa)
poldip3Polymerase (DNA-directed), delta interacting protein 3. (581 aa)
styxSerine/threonine/tyrosine interacting protein. (259 aa)
LOC102312867Actin binding Rho activating protein a. (356 aa)
LOC102308632Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (787 aa)
mcm3apMinichromosome maintenance complex component 3 associated protein. (2105 aa)
LOC102294846Akirin 2. (195 aa)
fbxo22F-box protein 22. (385 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (904 aa)
abraActin binding Rho activating protein b. (412 aa)
ipo4Importin 4. (1066 aa)
desi1Desumoylating isopeptidase 1b. (167 aa)
nup58Nucleoporin 58. (599 aa)
thoc3THO complex 3. (322 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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