61 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	anapc7	Anaphase promoting complex subunit 7. (565 aa)
	haspin	Si:dkeyp-26a9.2. (1217 aa)
	igf2	Insulin-like growth factor 2b. (215 aa)
	FBXO43	F-box protein 43. (690 aa)
	zw10	Zw10 kinetochore protein. (766 aa)
	mad1l1	Mitotic arrest deficient 1 like 1. (672 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (607 aa)
	lcmt1	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (325 aa)
	edn1	Endothelin 1. (201 aa)
	bora	Bora aurora kinase A activator. (543 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (460 aa)
	anapc15	Anaphase promoting complex subunit 15. (122 aa)
	LOC102294683	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
	ttk	Ttk protein kinase. (1006 aa)
	rgcc	Regulator of cell cycle. (128 aa)
	klhl22	Kelch-like family member 22. (638 aa)
	anapc5	Anaphase promoting complex subunit 5. (771 aa)
	nme6	Nucleoside diphosphate kinase. (182 aa)
	nsmce2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)
	mtbp	MDM2 binding protein. (869 aa)
	LOC102289283	EGF-like domain-containing protein. (154 aa)
	LOC102288968	Epithelial mitogen homolog (mouse). (164 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (721 aa)
	ndc80	NDC80 kinetochore complex component. (639 aa)
	ENSHBUP00000025695	CDK5 regulatory subunit associated protein 2. (1140 aa)
	LOC102291667	Aurora kinase B; Belongs to the protein kinase superfamily. (305 aa)
	rb1	Retinoblastoma 1. (912 aa)
	anapc11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (94 aa)
	fbxw5	F-box and WD repeat domain containing 5. (638 aa)
	mki67	Marker of proliferation Ki-67. (1892 aa)
	LOC102310023	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (515 aa)
	LOC102305789	Transforming growth factor, alpha. (254 aa)
	cdc23	CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
	ENSHBUP00000019377	MAD2L1 binding protein. (285 aa)
	rcc1	Regulator of chromosome condensation 1. (418 aa)
	ENSHBUP00000018194	Cnn_1N domain-containing protein. (61 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (766 aa)
	LOC102296327	Translocated promoter region a, nuclear basket protein. (1747 aa)
	bub3	BUB3 mitotic checkpoint protein. (326 aa)
	ZNF207	Zinc finger protein 207, b. (472 aa)
	bub1b	BUB1 mitotic checkpoint serine/threonine kinase Bb. (426 aa)
	cdc27	Cell division cycle 27. (802 aa)
	LOC102314648	Zinc finger protein 207. (461 aa)
	gen1	Uncharacterized protein. (887 aa)
	zwilch	Zwilch kinetochore protein. (609 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
	ENSHBUP00000007186	Uncharacterized protein. (190 aa)
	cul9	Uncharacterized protein; Belongs to the cullin family. (1619 aa)
	cdca2	PP1-binding domain-containing protein. (578 aa)
	kntc1	Kinetochore associated 1. (2083 aa)
	ENSHBUP00000005062	Uncharacterized protein. (143 aa)
	ENSHBUP00000005048	TAN domain-containing protein. (177 aa)
	fbxo5	F-box protein 5. (428 aa)
	pdgfb	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (549 aa)
	btc	Betacellulin, epidermal growth factor family member. (172 aa)
	xrcc3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (336 aa)
	tpr	Translocated promoter region b, nuclear basket protein. (2192 aa)
	spdl1	Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (574 aa)
	ENSHBUP00000002232	Uncharacterized protein. (176 aa)
	LOC102299736	Interleukin-1. (114 aa)
	bub1	BUB1 mitotic checkpoint serine/threonine kinase. (1199 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	ENSHBUP00000007186	ENSHBUP00000017979	ENSHBUP00000007186	Cullin 3; Belongs to the cullin family.	Uncharacterized protein.	0.573
CUL3	FBXO43	ENSHBUP00000017979	ENSHBUP00000033562	Cullin 3; Belongs to the cullin family.	F-box protein 43.	0.698
CUL3	LOC102291667	ENSHBUP00000017979	ENSHBUP00000025010	Cullin 3; Belongs to the cullin family.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.774
CUL3	LOC102294683	ENSHBUP00000017979	ENSHBUP00000030288	Cullin 3; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.829
CUL3	bora	ENSHBUP00000017979	ENSHBUP00000031034	Cullin 3; Belongs to the cullin family.	Bora aurora kinase A activator.	0.696
CUL3	cdc27	ENSHBUP00000017979	ENSHBUP00000013501	Cullin 3; Belongs to the cullin family.	Cell division cycle 27.	0.497
CUL3	cdt1	ENSHBUP00000017979	ENSHBUP00000031760	Cullin 3; Belongs to the cullin family.	Chromatin licensing and DNA replication factor 1.	0.538
CUL3	chek1	ENSHBUP00000017979	ENSHBUP00000030727	Cullin 3; Belongs to the cullin family.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.641
CUL3	cul9	ENSHBUP00000017979	ENSHBUP00000007060	Cullin 3; Belongs to the cullin family.	Uncharacterized protein; Belongs to the cullin family.	0.573
CUL3	fbxo5	ENSHBUP00000017979	ENSHBUP00000004978	Cullin 3; Belongs to the cullin family.	F-box protein 5.	0.698
CUL3	fbxw5	ENSHBUP00000017979	ENSHBUP00000020645	Cullin 3; Belongs to the cullin family.	F-box and WD repeat domain containing 5.	0.859
CUL3	klhl22	ENSHBUP00000017979	ENSHBUP00000029055	Cullin 3; Belongs to the cullin family.	Kelch-like family member 22.	0.897
CUL3	mtbp	ENSHBUP00000017979	ENSHBUP00000028252	Cullin 3; Belongs to the cullin family.	MDM2 binding protein.	0.404
CUL3	rb1	ENSHBUP00000017979	ENSHBUP00000022750	Cullin 3; Belongs to the cullin family.	Retinoblastoma 1.	0.646
CUL3	rcc1	ENSHBUP00000017979	ENSHBUP00000018695	Cullin 3; Belongs to the cullin family.	Regulator of chromosome condensation 1.	0.587
CUL3	xrcc3	ENSHBUP00000017979	ENSHBUP00000004362	Cullin 3; Belongs to the cullin family.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.419
ENSHBUP00000005048	ENSHBUP00000005062	ENSHBUP00000005048	ENSHBUP00000005062	TAN domain-containing protein.	Uncharacterized protein.	0.923
ENSHBUP00000005048	chek1	ENSHBUP00000005048	ENSHBUP00000030727	TAN domain-containing protein.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.950
ENSHBUP00000005048	gen1	ENSHBUP00000005048	ENSHBUP00000012590	TAN domain-containing protein.	Uncharacterized protein.	0.771
ENSHBUP00000005048	xrcc3	ENSHBUP00000005048	ENSHBUP00000004362	TAN domain-containing protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.863