(50 nodes) GDP binding network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102298584	RAB5A, member RAS oncogene family, a. (216 aa)
	RALB	RAS like proto-oncogene B. (207 aa)
	LOC102293940	Si:dkey-16l2.16. (224 aa)
	LOC102313044	RAP2B, member of RAS oncogene family. (182 aa)
	ENSHBUP00000018199	ADP-ribosylation factor 6b. (112 aa)
	RAP2A	RAP2A, member of RAS oncogene family. (183 aa)
	RAB9A	RAB9A, member RAS oncogene family. (202 aa)
	LOC102300410	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (206 aa)
	TMEM19	Transmembrane protein 19. (355 aa)
	RAB28	RAB28, member RAS oncogene family. (222 aa)
	rab5a	RAB5A, member RAS oncogene family, b. (216 aa)
	RAB31	RAB31, member RAS oncogene family. (194 aa)
	trim23	Tripartite motif containing 23. (614 aa)
	rab12	RAB12, member RAS oncogene family. (243 aa)
	LOC102309316	Uncharacterized protein. (185 aa)
	LOC102311874	Uncharacterized protein. (354 aa)
	RAB29	RAB29, member RAS oncogene family. (207 aa)
	LOC102303948	V-ral simian leukemia viral oncogene homolog Aa (ras related). (206 aa)
	rab27a	RAB27A, member RAS oncogene family. (220 aa)
	rras2	RAS related 2. (202 aa)
	ENSHBUP00000031114	ADP-ribosylation factor-like 2. (138 aa)
	LOC102300598	RAS related. (196 aa)
	LOC102299354	Uncharacterized protein. (201 aa)
	LOC102302896	Uncharacterized protein. (215 aa)
	LOC102306830	RAB5B, member RAS oncogene family. (216 aa)
	LOC102302368	Uncharacterized protein. (354 aa)
	rragc	Ras-related GTP binding Ca. (382 aa)
	arl3	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (217 aa)
	rerg	RAS like estrogen regulated growth inhibitor. (200 aa)
	LOC102299497	RAP1A, member of RAS oncogene family a. (185 aa)
	ENSHBUP00000010975	Uncharacterized protein. (198 aa)
	diras1	Uncharacterized protein. (199 aa)
	rab27b	RAB27B, member RAS oncogene family. (218 aa)
	rab35	RAB35, member RAS oncogene family b. (201 aa)
	RAB17	RAB17, member RAS oncogene family. (227 aa)
	ENSHBUP00000000431	RAB9B, member RAS oncogene family. (222 aa)
	LOC102296624	Uncharacterized protein. (381 aa)
	rab5c	RAB5C, member RAS oncogene family. (220 aa)
	rab21	RAB21, member RAS oncogene family. (219 aa)
	rab22a	RAB22A, member RAS oncogene family. (243 aa)
	LOC102290263	Ras-related GTP binding D. (416 aa)
	rap1b	Uncharacterized protein. (184 aa)
	srp54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	LOC102293273	Uncharacterized protein. (215 aa)
	LOC102306621	Uncharacterized protein. (222 aa)
	LOC102291626	Uncharacterized protein. (237 aa)
	LOC102296551	RAP2A, member of RAS oncogene family b. (183 aa)
	LOC102310638	DIRAS family, GTP-binding RAS-like 1b. (198 aa)
	LOC102308841	RAP2C, member of RAS oncogene family. (183 aa)
	mras	Muscle RAS oncogene homolog. (208 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000000431	ENSHBUP00000010975	ENSHBUP00000000431	ENSHBUP00000010975	RAB9B, member RAS oncogene family.	Uncharacterized protein.	0.853
ENSHBUP00000000431	ENSHBUP00000018199	ENSHBUP00000000431	ENSHBUP00000018199	RAB9B, member RAS oncogene family.	ADP-ribosylation factor 6b.	0.436
ENSHBUP00000000431	LOC102293273	ENSHBUP00000000431	ENSHBUP00000004703	RAB9B, member RAS oncogene family.	Uncharacterized protein.	0.474
ENSHBUP00000000431	LOC102298584	ENSHBUP00000000431	ENSHBUP00000002543	RAB9B, member RAS oncogene family.	RAB5A, member RAS oncogene family, a.	0.658
ENSHBUP00000000431	LOC102302896	ENSHBUP00000000431	ENSHBUP00000034770	RAB9B, member RAS oncogene family.	Uncharacterized protein.	0.473
ENSHBUP00000000431	LOC102306621	ENSHBUP00000000431	ENSHBUP00000005427	RAB9B, member RAS oncogene family.	Uncharacterized protein.	0.659
ENSHBUP00000000431	LOC102306830	ENSHBUP00000000431	ENSHBUP00000006690	RAB9B, member RAS oncogene family.	RAB5B, member RAS oncogene family.	0.655
ENSHBUP00000000431	RAB17	ENSHBUP00000000431	ENSHBUP00000000305	RAB9B, member RAS oncogene family.	RAB17, member RAS oncogene family.	0.669
ENSHBUP00000000431	RAB28	ENSHBUP00000000431	ENSHBUP00000024928	RAB9B, member RAS oncogene family.	RAB28, member RAS oncogene family.	0.455
ENSHBUP00000000431	RAB31	ENSHBUP00000000431	ENSHBUP00000025935	RAB9B, member RAS oncogene family.	RAB31, member RAS oncogene family.	0.647
ENSHBUP00000000431	RAB9A	ENSHBUP00000000431	ENSHBUP00000020405	RAB9B, member RAS oncogene family.	RAB9A, member RAS oncogene family.	0.852
ENSHBUP00000000431	rab12	ENSHBUP00000000431	ENSHBUP00000026068	RAB9B, member RAS oncogene family.	RAB12, member RAS oncogene family.	0.471
ENSHBUP00000000431	rab21	ENSHBUP00000000431	ENSHBUP00000002014	RAB9B, member RAS oncogene family.	RAB21, member RAS oncogene family.	0.401
ENSHBUP00000000431	rab22a	ENSHBUP00000000431	ENSHBUP00000002226	RAB9B, member RAS oncogene family.	RAB22A, member RAS oncogene family.	0.654
ENSHBUP00000000431	rab5a	ENSHBUP00000000431	ENSHBUP00000025707	RAB9B, member RAS oncogene family.	RAB5A, member RAS oncogene family, b.	0.658
ENSHBUP00000000431	rab5c	ENSHBUP00000000431	ENSHBUP00000000820	RAB9B, member RAS oncogene family.	RAB5C, member RAS oncogene family.	0.659
ENSHBUP00000010975	ENSHBUP00000000431	ENSHBUP00000010975	ENSHBUP00000000431	Uncharacterized protein.	RAB9B, member RAS oncogene family.	0.853
ENSHBUP00000010975	ENSHBUP00000018199	ENSHBUP00000010975	ENSHBUP00000018199	Uncharacterized protein.	ADP-ribosylation factor 6b.	0.436
ENSHBUP00000010975	LOC102293273	ENSHBUP00000010975	ENSHBUP00000004703	Uncharacterized protein.	Uncharacterized protein.	0.454
ENSHBUP00000010975	LOC102298584	ENSHBUP00000010975	ENSHBUP00000002543	Uncharacterized protein.	RAB5A, member RAS oncogene family, a.	0.642