44 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ndc80	NDC80 kinetochore complex component. (639 aa)
	zw10	Zw10 kinetochore protein. (766 aa)
	cdc26	Cell division cycle 26 homolog. (87 aa)
	mad1l1	Mitotic arrest deficient 1 like 1. (672 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (607 aa)
	lcmt1	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (325 aa)
	anapc15	Anaphase promoting complex subunit 15. (122 aa)
	LOC102294683	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
	ttk	Ttk protein kinase. (1006 aa)
	anapc4	Anaphase promoting complex subunit 4. (756 aa)
	klhl22	Kelch-like family member 22. (638 aa)
	anapc5	Anaphase promoting complex subunit 5. (771 aa)
	nsmce2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)
	ENSHBUP00000025695	CDK5 regulatory subunit associated protein 2. (1140 aa)
	LOC102291667	Aurora kinase B; Belongs to the protein kinase superfamily. (305 aa)
	rb1	Retinoblastoma 1. (912 aa)
	anapc11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (94 aa)
	cdc23	CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
	ENSHBUP00000019377	MAD2L1 binding protein. (285 aa)
	ENSHBUP00000018194	Cnn_1N domain-containing protein. (61 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (766 aa)
	LOC102296327	Translocated promoter region a, nuclear basket protein. (1747 aa)
	bub3	BUB3 mitotic checkpoint protein. (326 aa)
	ZNF207	Zinc finger protein 207, b. (472 aa)
	bub1b	BUB1 mitotic checkpoint serine/threonine kinase Bb. (426 aa)
	cdc27	Cell division cycle 27. (802 aa)
	LOC102314648	Zinc finger protein 207. (461 aa)
	gen1	Uncharacterized protein. (887 aa)
	zwilch	Zwilch kinetochore protein. (609 aa)
	bcl7a	BAF chromatin remodeling complex subunit BCL7A. (199 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
	riok2	RIO kinase 2 (yeast). (527 aa)
	ube2c	Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
	ENSHBUP00000006166	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (154 aa)
	kntc1	Kinetochore associated 1. (2083 aa)
	cdc6	Cell division cycle 6 homolog (S. cerevisiae). (429 aa)
	ENSHBUP00000005062	Uncharacterized protein. (143 aa)
	ENSHBUP00000005048	TAN domain-containing protein. (177 aa)
	xrcc3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (336 aa)
	tpr	Translocated promoter region b, nuclear basket protein. (2192 aa)
	spdl1	Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (574 aa)
	haspin	Si:dkeyp-26a9.2. (1217 aa)
	bub1	BUB1 mitotic checkpoint serine/threonine kinase. (1199 aa)
	anapc7	Anaphase promoting complex subunit 7. (565 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	LOC102291667	ENSHBUP00000017979	ENSHBUP00000025010	Cullin 3; Belongs to the cullin family.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.774
CUL3	LOC102294683	ENSHBUP00000017979	ENSHBUP00000030288	Cullin 3; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.829
CUL3	cdc27	ENSHBUP00000017979	ENSHBUP00000013501	Cullin 3; Belongs to the cullin family.	Cell division cycle 27.	0.497
CUL3	cdc6	ENSHBUP00000017979	ENSHBUP00000005263	Cullin 3; Belongs to the cullin family.	Cell division cycle 6 homolog (S. cerevisiae).	0.859
CUL3	cdt1	ENSHBUP00000017979	ENSHBUP00000031760	Cullin 3; Belongs to the cullin family.	Chromatin licensing and DNA replication factor 1.	0.538
CUL3	klhl22	ENSHBUP00000017979	ENSHBUP00000029055	Cullin 3; Belongs to the cullin family.	Kelch-like family member 22.	0.897
CUL3	rb1	ENSHBUP00000017979	ENSHBUP00000022750	Cullin 3; Belongs to the cullin family.	Retinoblastoma 1.	0.646
CUL3	ube2c	ENSHBUP00000017979	ENSHBUP00000006974	Cullin 3; Belongs to the cullin family.	Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family.	0.644
CUL3	xrcc3	ENSHBUP00000017979	ENSHBUP00000004362	Cullin 3; Belongs to the cullin family.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.419
ENSHBUP00000005048	ENSHBUP00000005062	ENSHBUP00000005048	ENSHBUP00000005062	TAN domain-containing protein.	Uncharacterized protein.	0.923
ENSHBUP00000005048	gen1	ENSHBUP00000005048	ENSHBUP00000012590	TAN domain-containing protein.	Uncharacterized protein.	0.771
ENSHBUP00000005048	xrcc3	ENSHBUP00000005048	ENSHBUP00000004362	TAN domain-containing protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.863
ENSHBUP00000005062	ENSHBUP00000005048	ENSHBUP00000005062	ENSHBUP00000005048	Uncharacterized protein.	TAN domain-containing protein.	0.923
ENSHBUP00000005062	gen1	ENSHBUP00000005062	ENSHBUP00000012590	Uncharacterized protein.	Uncharacterized protein.	0.771
ENSHBUP00000005062	xrcc3	ENSHBUP00000005062	ENSHBUP00000004362	Uncharacterized protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.863
ENSHBUP00000006166	LOC102291667	ENSHBUP00000006166	ENSHBUP00000025010	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.730
ENSHBUP00000006166	bub1	ENSHBUP00000006166	ENSHBUP00000000771	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	BUB1 mitotic checkpoint serine/threonine kinase.	0.987
ENSHBUP00000006166	bub1b	ENSHBUP00000006166	ENSHBUP00000014138	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	BUB1 mitotic checkpoint serine/threonine kinase Bb.	0.990
ENSHBUP00000006166	bub3	ENSHBUP00000006166	ENSHBUP00000017164	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	BUB3 mitotic checkpoint protein.	0.882
ENSHBUP00000006166	cdc27	ENSHBUP00000006166	ENSHBUP00000013501	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Cell division cycle 27.	0.444