99 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gpc3	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (581 aa)
	LOC102307482	X-linked inhibitor of apoptosis. (421 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (290 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (515 aa)
	LOC102299747	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (446 aa)
	LOC102305108	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (290 aa)
	LOC102306408	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (937 aa)
	LOC102306465	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	dab2	DAB adaptor protein 2. (779 aa)
	reck	Reversion-inducing-cysteine-rich protein with kazal motifs. (840 aa)
	ilk	Uncharacterized protein. (452 aa)
	LOC102305557	Casein kinase 1 delta; Belongs to the protein kinase superfamily. (404 aa)
	rspo1	R-spondin 1. (276 aa)
	tmem198	Transmembrane protein 198b. (364 aa)
	eda	Ectodysplasin A; Belongs to the tumor necrosis factor family. (372 aa)
	rspo3	R-spondin 3. (309 aa)
	RNF146	Ring finger protein 146. (402 aa)
	LOC102293099	DUF4203 domain-containing protein. (335 aa)
	LOC102293232	Extracellular sulfatase. (884 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (818 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1383 aa)
	LOC102300092	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
	LOC102304610	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
	cdc73	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (512 aa)
	LOC102298147	Uncharacterized protein. (836 aa)
	LOC102312035	Ring finger protein 146. (354 aa)
	LYPD6	LY6/PLAUR domain containing 6. (175 aa)
	lef1	Lymphoid enhancer-binding factor 1. (398 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2426 aa)
	ENSHBUP00000031370	Dickkopf_N domain-containing protein. (256 aa)
	LOC102293464	WNK lysine deficient protein kinase 2. (2299 aa)
	LOC102306173	G protein-coupled receptor, class C, group 5, member Bb. (422 aa)
	PRDM15	PR/SET domain 15. (1078 aa)
	fam53b	Family with sequence similarity 53 member B. (419 aa)
	ENSHBUP00000033800	APC membrane recruitment protein 1. (832 aa)
	LOC102299315	WNK lysine deficient protein kinase 2. (2598 aa)
	CSNK1D	Casein kinase 1 delta. (426 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (783 aa)
	atp6ap2	ATPase H+ transporting accessory protein 2. (362 aa)
	gpc5	Glypican 5a; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (569 aa)
	LOC102298693	Transmembrane protein 198a. (390 aa)
	LOC102308736	Glypican 5c; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (607 aa)
	ENSHBUP00000002056	G_PROTEIN_RECEP_F1_2 domain-containing protein. (759 aa)
	LOC102300800	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (626 aa)
	LOC102300060	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
	LOC102307143	Casein kinase 1, epsilon; Belongs to the protein kinase superfamily. (420 aa)
	LOC102298407	DUF4203 domain-containing protein. (340 aa)
	LOC102314302	Casein kinase 1 gamma 2; Belongs to the protein kinase superfamily. (453 aa)
	gid8	GID complex subunit 8 homolog b (S. cerevisiae). (229 aa)
	ttc21b	Tetratricopeptide repeat domain 21B. (1318 aa)
	USP34	Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (2852 aa)
	ENSHBUP00000005913	Uncharacterized protein. (289 aa)
	ENSHBUP00000005928	Ankyrin repeat domain 6b. (286 aa)
	ENSHBUP00000006154	Leucine-rich repeat kinase 1. (664 aa)
	wls	Wnt ligand secretion mediator. (433 aa)
	VANGL2	Vang-like protein. (525 aa)
	scel	LIM zinc-binding domain-containing protein. (506 aa)
	ppm1a	Protein phosphatase, Mg2+/Mn2+ dependent, 1Aa. (387 aa)
	LOC102307724	Transducin beta like 1 X-linked. (534 aa)
	abl1	Tyrosine-protein kinase. (1104 aa)
	LOC102303699	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (442 aa)
	ubr5	Ubiquitin protein ligase E3 component n-recognin 5. (2426 aa)
	abl2	Tyrosine-protein kinase. (1201 aa)
	LOC102302417	DISC1 scaffold protein. (815 aa)
	LOC102299711	Poly [ADP-ribose] polymerase. (1279 aa)
	LOC102292039	Ring finger protein 220a. (370 aa)
	RNF220	RNF220 domain-containing protein. (328 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	LOC102310967	Protein phosphatase, Mg2+/Mn2+ dependent, 1Bb. (473 aa)
	csnk1g1	Casein kinase 1, gamma 1; Belongs to the protein kinase superfamily. (468 aa)
	sulf1	Sulfatase 1. (1163 aa)
	zranb1	Zinc finger, RAN-binding domain containing 1a. (712 aa)
	LOC102312769	Protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative). (435 aa)
	plekha4	PH domain-containing protein. (675 aa)
	LOC102303803	Transducin (beta)-like 1 X-linked receptor 1b. (512 aa)
	ILK	Integrin linked kinase. (452 aa)
	ZRANB1	Zinc finger RANBP2-type containing 1. (799 aa)
	FAM53B	Family with sequence similarity 53 member B. (435 aa)
	pin1	Peptidyl-prolyl cis-trans isomerase. (156 aa)
	dkk2	Dickkopf WNT signaling pathway inhibitor 2. (241 aa)
	ENSHBUP00000013761	Secreted frizzled-related protein 2 like. (310 aa)
	nle1	Notchless homolog 1 (Drosophila). (535 aa)
	lgr4	Leucine-rich repeat containing G protein-coupled receptor 4. (984 aa)
	rspo2	R-spondin 2. (245 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
	ppm1b	Protein phosphatase, Mg2+/Mn2+ dependent, 1Ba. (396 aa)
	gprc5b	G protein-coupled receptor, class C, group 5, member Ba. (394 aa)
	LOC102309572	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (165 aa)
	adgra2	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1377 aa)
	LOC102291596	C1q domain-containing protein. (900 aa)
	GID8	GID complex subunit 8 homolog. (229 aa)
	LOC102291259	Poly [ADP-ribose] polymerase. (1263 aa)
	WLS	Uncharacterized protein. (536 aa)
	LOC102313151	Vang-like protein. (526 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1111 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1036 aa)
	ENSHBUP00000021071	Ring finger protein 220b. (334 aa)
	bambi	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSNK1D	ENSHBUP00000021071	ENSHBUP00000035073	ENSHBUP00000021071	Casein kinase 1 delta.	Ring finger protein 220b.	0.405
CSNK1D	LOC102292039	ENSHBUP00000035073	ENSHBUP00000018225	Casein kinase 1 delta.	Ring finger protein 220a.	0.405
CSNK1D	LOC102300092	ENSHBUP00000035073	ENSHBUP00000029430	Casein kinase 1 delta.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.526
CSNK1D	LOC102303699	ENSHBUP00000035073	ENSHBUP00000020064	Casein kinase 1 delta.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.745
CSNK1D	LOC102305557	ENSHBUP00000035073	ENSHBUP00000026728	Casein kinase 1 delta.	Casein kinase 1 delta; Belongs to the protein kinase superfamily.	0.829
CSNK1D	LOC102307143	ENSHBUP00000035073	ENSHBUP00000003192	Casein kinase 1 delta.	Casein kinase 1, epsilon; Belongs to the protein kinase superfamily.	0.745
CSNK1D	LOC102314302	ENSHBUP00000035073	ENSHBUP00000003614	Casein kinase 1 delta.	Casein kinase 1 gamma 2; Belongs to the protein kinase superfamily.	0.527
CSNK1D	RNF220	ENSHBUP00000035073	ENSHBUP00000018217	Casein kinase 1 delta.	RNF220 domain-containing protein.	0.405
CSNK1D	csnk1g1	ENSHBUP00000035073	ENSHBUP00000017770	Casein kinase 1 delta.	Casein kinase 1, gamma 1; Belongs to the protein kinase superfamily.	0.522
CSNK1D	ctnnb1	ENSHBUP00000035073	ENSHBUP00000035228	Casein kinase 1 delta.	Catenin (cadherin-associated protein), beta 1.	0.678
CSNK1D	plekha4	ENSHBUP00000035073	ENSHBUP00000016147	Casein kinase 1 delta.	PH domain-containing protein.	0.406
ENSHBUP00000002056	LGR6	ENSHBUP00000002056	ENSHBUP00000024876	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Leucine rich repeat containing G protein-coupled receptor 6.	0.873
ENSHBUP00000002056	PTK7	ENSHBUP00000002056	ENSHBUP00000008491	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.700
ENSHBUP00000002056	ctnnb1	ENSHBUP00000002056	ENSHBUP00000035228	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Catenin (cadherin-associated protein), beta 1.	0.450
ENSHBUP00000002056	eda	ENSHBUP00000002056	ENSHBUP00000027841	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Ectodysplasin A; Belongs to the tumor necrosis factor family.	0.418
ENSHBUP00000002056	lgr4	ENSHBUP00000002056	ENSHBUP00000013085	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.872
ENSHBUP00000002056	rspo1	ENSHBUP00000002056	ENSHBUP00000026897	G_PROTEIN_RECEP_F1_2 domain-containing protein.	R-spondin 1.	0.986
ENSHBUP00000002056	rspo2	ENSHBUP00000002056	ENSHBUP00000013036	G_PROTEIN_RECEP_F1_2 domain-containing protein.	R-spondin 2.	0.931
ENSHBUP00000002056	rspo3	ENSHBUP00000002056	ENSHBUP00000028435	G_PROTEIN_RECEP_F1_2 domain-containing protein.	R-spondin 3.	0.946
ENSHBUP00000002056	wnt3a	ENSHBUP00000002056	ENSHBUP00000007164	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.410