(9 nodes) HOPS complex network (Haplochromis burtoni)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	hook2	Hook microtubule-tethering protein 2. (708 aa)
	vps11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (907 aa)
	vps18	VPS18 core subunit of CORVET and HOPS complexes. (986 aa)
	vps16	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (834 aa)
	vps41	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (882 aa)
	LOC102298258	Syntaxin 17; Belongs to the syntaxin family. (303 aa)
	ENSHBUP00000017161	CNH domain-containing protein. (246 aa)
	vps33a	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (618 aa)
	vps39	VPS39 subunit of HOPS complex. (678 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000017161	LOC102298258	ENSHBUP00000017161	ENSHBUP00000014420	CNH domain-containing protein.	Syntaxin 17; Belongs to the syntaxin family.	0.950
ENSHBUP00000017161	vps11	ENSHBUP00000017161	ENSHBUP00000019588	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.993
ENSHBUP00000017161	vps16	ENSHBUP00000017161	ENSHBUP00000005733	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.993
ENSHBUP00000017161	vps18	ENSHBUP00000017161	ENSHBUP00000020370	CNH domain-containing protein.	VPS18 core subunit of CORVET and HOPS complexes.	0.992
ENSHBUP00000017161	vps33a	ENSHBUP00000017161	ENSHBUP00000028071	CNH domain-containing protein.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.992
ENSHBUP00000017161	vps39	ENSHBUP00000017161	ENSHBUP00000017182	CNH domain-containing protein.	VPS39 subunit of HOPS complex.	0.927
ENSHBUP00000017161	vps41	ENSHBUP00000017161	ENSHBUP00000014070	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.992
LOC102298258	ENSHBUP00000017161	ENSHBUP00000014420	ENSHBUP00000017161	Syntaxin 17; Belongs to the syntaxin family.	CNH domain-containing protein.	0.950
LOC102298258	vps11	ENSHBUP00000014420	ENSHBUP00000019588	Syntaxin 17; Belongs to the syntaxin family.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.839
LOC102298258	vps16	ENSHBUP00000014420	ENSHBUP00000005733	Syntaxin 17; Belongs to the syntaxin family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.922
LOC102298258	vps18	ENSHBUP00000014420	ENSHBUP00000020370	Syntaxin 17; Belongs to the syntaxin family.	VPS18 core subunit of CORVET and HOPS complexes.	0.879
LOC102298258	vps33a	ENSHBUP00000014420	ENSHBUP00000028071	Syntaxin 17; Belongs to the syntaxin family.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.796
LOC102298258	vps39	ENSHBUP00000014420	ENSHBUP00000017182	Syntaxin 17; Belongs to the syntaxin family.	VPS39 subunit of HOPS complex.	0.950
LOC102298258	vps41	ENSHBUP00000014420	ENSHBUP00000014070	Syntaxin 17; Belongs to the syntaxin family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.959
vps11	ENSHBUP00000017161	ENSHBUP00000019588	ENSHBUP00000017161	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	CNH domain-containing protein.	0.993
vps11	LOC102298258	ENSHBUP00000019588	ENSHBUP00000014420	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Syntaxin 17; Belongs to the syntaxin family.	0.839
vps11	vps16	ENSHBUP00000019588	ENSHBUP00000005733	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.999
vps11	vps18	ENSHBUP00000019588	ENSHBUP00000020370	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS18 core subunit of CORVET and HOPS complexes.	0.999
vps11	vps33a	ENSHBUP00000019588	ENSHBUP00000028071	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.995
vps11	vps39	ENSHBUP00000019588	ENSHBUP00000017182	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS39 subunit of HOPS complex.	0.993