27 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pex2	Peroxisomal biogenesis factor 2. (351 aa)
	fbxo4	F-box protein 4. (396 aa)
	LOC102298011	Small EDRK-rich factor 2. (56 aa)
	xbp1	X-box binding protein 1. (260 aa)
	gga3	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b. (697 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (715 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (432 aa)
	isoc2	Isochorismatase domain containing 2. (213 aa)
	htt	Huntingtin. (2575 aa)
	LOC102294444	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a. (762 aa)
	LOC102302421	Nuclear receptor subfamily 1, group d, member 1. (597 aa)
	utp25	UTP25 small subunit processor component. (762 aa)
	ep300	E1A binding protein p300 b. (2764 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (766 aa)
	ENSHBUP00000018381	Ring finger protein 139. (498 aa)
	sirt6	Sirtuin 6. (351 aa)
	LOC102306757	E1A binding protein p300 a. (2600 aa)
	LOC102310016	Nuclear receptor subfamily 1, group D, member 4b. (587 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	LOC102293257	Uncharacterized protein. (2253 aa)
	fbxw11	F-box and WD repeat domain containing 11a. (562 aa)
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
	cdc73	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (512 aa)
	LOC102294683	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
	LOC102306633	CREB binding protein a. (2475 aa)
	ctsh	Cathepsin H; Belongs to the peptidase C1 family. (324 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (329 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	LOC102294683	ENSHBUP00000017979	ENSHBUP00000030288	Cullin 3; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.829
CUL3	fbxo4	ENSHBUP00000017979	ENSHBUP00000002791	Cullin 3; Belongs to the cullin family.	F-box protein 4.	0.821
CUL3	fbxw11	ENSHBUP00000017979	ENSHBUP00000026439	Cullin 3; Belongs to the cullin family.	F-box and WD repeat domain containing 11a.	0.984
CUL3	prkn	ENSHBUP00000017979	ENSHBUP00000010501	Cullin 3; Belongs to the cullin family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.403
ENSHBUP00000018381	derl1	ENSHBUP00000018381	ENSHBUP00000027033	Ring finger protein 139.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.841
ENSHBUP00000018381	xbp1	ENSHBUP00000018381	ENSHBUP00000008913	Ring finger protein 139.	X-box binding protein 1.	0.496
LOC102293257	LOC102306633	ENSHBUP00000025589	ENSHBUP00000030717	Uncharacterized protein.	CREB binding protein a.	0.849
LOC102293257	LOC102306757	ENSHBUP00000025589	ENSHBUP00000020755	Uncharacterized protein.	E1A binding protein p300 a.	0.986
LOC102293257	ep300	ENSHBUP00000025589	ENSHBUP00000015535	Uncharacterized protein.	E1A binding protein p300 b.	0.986
LOC102293257	htt	ENSHBUP00000025589	ENSHBUP00000013215	Uncharacterized protein.	Huntingtin.	0.814
LOC102293257	sirt1	ENSHBUP00000025589	ENSHBUP00000009767	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.722
LOC102293257	sirt6	ENSHBUP00000025589	ENSHBUP00000019117	Uncharacterized protein.	Sirtuin 6.	0.454
LOC102294683	CUL3	ENSHBUP00000030288	ENSHBUP00000017979	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cullin 3; Belongs to the cullin family.	0.829
LOC102294683	fbxo4	ENSHBUP00000030288	ENSHBUP00000002791	CULLIN_2 domain-containing protein; Belongs to the cullin family.	F-box protein 4.	0.821
LOC102294683	fbxw11	ENSHBUP00000030288	ENSHBUP00000026439	CULLIN_2 domain-containing protein; Belongs to the cullin family.	F-box and WD repeat domain containing 11a.	0.984
LOC102294683	prkn	ENSHBUP00000030288	ENSHBUP00000010501	CULLIN_2 domain-containing protein; Belongs to the cullin family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.403
LOC102302421	LOC102306757	ENSHBUP00000014651	ENSHBUP00000020755	Nuclear receptor subfamily 1, group d, member 1.	E1A binding protein p300 a.	0.427
LOC102302421	ep300	ENSHBUP00000014651	ENSHBUP00000015535	Nuclear receptor subfamily 1, group d, member 1.	E1A binding protein p300 b.	0.427
LOC102306633	LOC102293257	ENSHBUP00000030717	ENSHBUP00000025589	CREB binding protein a.	Uncharacterized protein.	0.849
LOC102306633	LOC102306757	ENSHBUP00000030717	ENSHBUP00000020755	CREB binding protein a.	E1A binding protein p300 a.	0.986