(16 nodes) Regulation of chromatin binding network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dtx3	Zgc:66440. (369 aa)
	btaf1	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated. (1859 aa)
	LOC102292484	RING-type domain-containing protein. (685 aa)
	nfatc4	Nuclear factor of activated T cells 4. (849 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (827 aa)
	LOC102289213	Thymine DNA glycosylase, tandem duplicate 2. (433 aa)
	LOC102313784	Thymine DNA glycosylase, tandem duplicate 1. (449 aa)
	wapl	WAPL cohesin release factor a. (1171 aa)
	LOC102300109	Si:dkey-3h3.3. (328 aa)
	LOC102313370	WAPL cohesin release factor b. (1213 aa)
	pygo2	Pygopus homolog 2 (Drosophila). (587 aa)
	ENSHBUP00000019957	Zinc finger protein 618. (798 aa)
	gmnn	Geminin DNA replication inhibitor. (227 aa)
	ENSHBUP00000034973	RING-type domain-containing protein. (720 aa)
	LOC102295288	RING-type domain-containing protein. (199 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (607 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102289213	LOC102313784	ENSHBUP00000007281	ENSHBUP00000007308	Thymine DNA glycosylase, tandem duplicate 2.	Thymine DNA glycosylase, tandem duplicate 1.	0.815
LOC102313370	btaf1	ENSHBUP00000011423	ENSHBUP00000002927	WAPL cohesin release factor b.	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.	0.443
LOC102313784	LOC102289213	ENSHBUP00000007308	ENSHBUP00000007281	Thymine DNA glycosylase, tandem duplicate 1.	Thymine DNA glycosylase, tandem duplicate 2.	0.815
btaf1	LOC102313370	ENSHBUP00000002927	ENSHBUP00000011423	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.	WAPL cohesin release factor b.	0.443
btaf1	wapl	ENSHBUP00000002927	ENSHBUP00000007674	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.	WAPL cohesin release factor a.	0.443
cdt1	gmnn	ENSHBUP00000031760	ENSHBUP00000022439	Chromatin licensing and DNA replication factor 1.	Geminin DNA replication inhibitor.	0.999
gmnn	cdt1	ENSHBUP00000022439	ENSHBUP00000031760	Geminin DNA replication inhibitor.	Chromatin licensing and DNA replication factor 1.	0.999
wapl	btaf1	ENSHBUP00000007674	ENSHBUP00000002927	WAPL cohesin release factor a.	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.	0.443