(31 nodes) ESCRT complex network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102296491	Uncharacterized protein. (268 aa)
	vps28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (267 aa)
	LOC102304887	UBA domain-containing protein. (368 aa)
	chmp2a	Charged multivesicular body protein 2A. (220 aa)
	chmp1b	Chromatin modifying protein 1B. (199 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (752 aa)
	vps37b	Zgc:114173. (282 aa)
	chmp4c	Charged multivesicular body protein 4C. (212 aa)
	vps36	Vacuolar protein sorting 36 homolog. (382 aa)
	CHMP4B	Charged multivesicular body protein 4B. (222 aa)
	vps37c	VPS37C subunit of ESCRT-I. (354 aa)
	LOC102313326	UEV and lactate/malate dehyrogenase domains. (470 aa)
	stam	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (751 aa)
	LOC102312367	Si:ch211-284f22.3. (304 aa)
	chmp1a	Charged multivesicular body protein 1A. (198 aa)
	chmp7	Charged multivesicular body protein 7. (450 aa)
	chmp2b	Charged multivesicular body protein 2Bb. (214 aa)
	mvb12a	MABP domain-containing protein. (286 aa)
	vps37a	VPS37A subunit of ESCRT-I. (416 aa)
	ubap1	Ubiquitin associated protein 1. (469 aa)
	LOC102308017	Charged multivesicular body protein 4Bb. (220 aa)
	LOC102294009	Uncharacterized protein. (200 aa)
	chmp6	Charged multivesicular body protein 6. (205 aa)
	LOC102300456	Charged multivesicular body protein 6a. (217 aa)
	snf8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (257 aa)
	vps25	Vacuolar protein sorting 25 homolog. (174 aa)
	mvb12b	Multivesicular body subunit 12Ba. (294 aa)
	tsg101	Tumor susceptibility 101a. (390 aa)
	LOC102289963	Zgc:123278. (192 aa)
	LOC102298630	Multivesicular body subunit 12Bb. (253 aa)
	chmp3	Charged multivesicular body protein 3. (220 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHMP4B	LOC102289963	ENSHBUP00000009734	ENSHBUP00000028342	Charged multivesicular body protein 4B.	Zgc:123278.	0.783
CHMP4B	LOC102294009	ENSHBUP00000009734	ENSHBUP00000022114	Charged multivesicular body protein 4B.	Uncharacterized protein.	0.892
CHMP4B	LOC102298630	ENSHBUP00000009734	ENSHBUP00000030123	Charged multivesicular body protein 4B.	Multivesicular body subunit 12Bb.	0.675
CHMP4B	LOC102300456	ENSHBUP00000009734	ENSHBUP00000023186	Charged multivesicular body protein 4B.	Charged multivesicular body protein 6a.	0.954
CHMP4B	LOC102308017	ENSHBUP00000009734	ENSHBUP00000020446	Charged multivesicular body protein 4B.	Charged multivesicular body protein 4Bb.	0.810
CHMP4B	LOC102312367	ENSHBUP00000009734	ENSHBUP00000011857	Charged multivesicular body protein 4B.	Si:ch211-284f22.3.	0.595
CHMP4B	LOC102313326	ENSHBUP00000009734	ENSHBUP00000010557	Charged multivesicular body protein 4B.	UEV and lactate/malate dehyrogenase domains.	0.715
CHMP4B	chmp1a	ENSHBUP00000009734	ENSHBUP00000035345	Charged multivesicular body protein 4B.	Charged multivesicular body protein 1A.	0.922
CHMP4B	chmp1b	ENSHBUP00000009734	ENSHBUP00000003263	Charged multivesicular body protein 4B.	Chromatin modifying protein 1B.	0.892
CHMP4B	chmp2a	ENSHBUP00000009734	ENSHBUP00000003262	Charged multivesicular body protein 4B.	Charged multivesicular body protein 2A.	0.983
CHMP4B	chmp2b	ENSHBUP00000009734	ENSHBUP00000012160	Charged multivesicular body protein 4B.	Charged multivesicular body protein 2Bb.	0.942
CHMP4B	chmp3	ENSHBUP00000009734	ENSHBUP00000034612	Charged multivesicular body protein 4B.	Charged multivesicular body protein 3.	0.986
CHMP4B	chmp4c	ENSHBUP00000009734	ENSHBUP00000007492	Charged multivesicular body protein 4B.	Charged multivesicular body protein 4C.	0.828
CHMP4B	chmp6	ENSHBUP00000009734	ENSHBUP00000022250	Charged multivesicular body protein 4B.	Charged multivesicular body protein 6.	0.954
CHMP4B	chmp7	ENSHBUP00000009734	ENSHBUP00000011863	Charged multivesicular body protein 4B.	Charged multivesicular body protein 7.	0.950
CHMP4B	hgs	ENSHBUP00000009734	ENSHBUP00000003610	Charged multivesicular body protein 4B.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.579
CHMP4B	mvb12a	ENSHBUP00000009734	ENSHBUP00000013856	Charged multivesicular body protein 4B.	MABP domain-containing protein.	0.665
CHMP4B	mvb12b	ENSHBUP00000009734	ENSHBUP00000025212	Charged multivesicular body protein 4B.	Multivesicular body subunit 12Ba.	0.675
CHMP4B	snf8	ENSHBUP00000009734	ENSHBUP00000023638	Charged multivesicular body protein 4B.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.922
CHMP4B	tsg101	ENSHBUP00000009734	ENSHBUP00000028331	Charged multivesicular body protein 4B.	Tumor susceptibility 101a.	0.783