(92 nodes) Dendritic spine network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bcr	Si:dkey-91m11.5. (1289 aa)
	dtnbp1	Dystrobrevin binding protein 1b. (270 aa)
	baiap2	BAI1 associated protein 2. (583 aa)
	LOC102305737	Uncharacterized protein. (1636 aa)
	LOC102308187	Amyloid beta (A4) precursor protein-binding, family A, member 2a. (834 aa)
	LOC102305150	Glutamate receptor, ionotropic, AMPA 3a. (886 aa)
	gria1	Glutamate receptor, ionotropic, AMPA 1a. (919 aa)
	LOC102309266	Shisa family member 9b. (375 aa)
	LOC102290636	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (623 aa)
	LOC102300760	BAI1-associated protein 2a. (560 aa)
	synpo	Uncharacterized protein. (1169 aa)
	LOC102288803	Abhydrolase domain containing 17A. (321 aa)
	ENSHBUP00000003545	Uncharacterized protein. (1121 aa)
	fxr1	Fragile X mental retardation, autosomal homolog 1. (734 aa)
	LOC102307328	Potassium voltage-gated channel, Shal-related subfamily, member 2; Belongs to the potassium channel family. (622 aa)
	pdlim4	PDZ and LIM domain 4. (364 aa)
	LOC102302011	Paralemmin 1a. (402 aa)
	LOC102303593	Potassium voltage-gated channel, Shal-related subfamily, member 3; Belongs to the potassium channel family. (644 aa)
	atp6ap2	ATPase H+ transporting accessory protein 2. (362 aa)
	ppp1r9b	Protein phosphatase 1, regulatory subunit 9Bb. (836 aa)
	ENSHBUP00000006778	Proline-rich transmembrane protein 2. (184 aa)
	ngfr	Nerve growth factor receptor a (TNFR superfamily, member 16). (357 aa)
	SYNDIG1	Synapse differentiation inducing 1. (282 aa)
	LOC102310269	Fragile X mental retardation, autosomal homolog 2. (672 aa)
	CDC42	Cell division cycle 42. (191 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1036 aa)
	usp50	Ubiquitin carboxyl-terminal hydrolase. (769 aa)
	ENSHBUP00000008174	SAM domain-containing protein. (1681 aa)
	shank3	SH3 and multiple ankyrin repeat domains 3a. (1971 aa)
	APBA1	Amyloid beta precursor protein binding family A member 1. (1024 aa)
	LOC102308165	Glutamate receptor, ionotropic, AMPA 4a. (817 aa)
	ptk2	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (980 aa)
	LOC102304452	Homer scaffold protein 1b. (363 aa)
	myl7	Myosin, light chain 7, regulatory. (170 aa)
	LOC102292924	Uncharacterized protein. (905 aa)
	LOC102294469	Uncharacterized protein. (191 aa)
	abhd17b	Abhydrolase domain containing 17B. (288 aa)
	ENSHBUP00000011914	Uncharacterized protein. (72 aa)
	ENSHBUP00000011925	Uncharacterized protein. (90 aa)
	dagla	Diacylglycerol lipase, alpha. (1001 aa)
	LOC102294236	Uncharacterized protein. (385 aa)
	LOC102306122	Amyloid beta (A4) precursor protein-binding, family A, member 2b. (955 aa)
	LOC102308881	Leucine zipper, putative tumor suppressor 1. (671 aa)
	ENSHBUP00000012612	SH3 and multiple ankyrin repeat domains 2a. (1498 aa)
	ENSHBUP00000012616	Uncharacterized protein. (120 aa)
	ENSHBUP00000013319	Uncharacterized protein. (158 aa)
	cttnbp2	Cortactin binding protein 2. (1664 aa)
	ENSHBUP00000013784	PDZ domain-containing protein. (111 aa)
	LOC102295479	Abhydrolase domain containing 17C. (94 aa)
	LOC102290399	Purinergic receptor P2X, ligand-gated ion channel, 3b. (159 aa)
	LOC102302421	Nuclear receptor subfamily 1, group d, member 1. (597 aa)
	dock10	Dedicator of cytokinesis 10; Belongs to the DOCK family. (2031 aa)
	LOC102288700	Uncharacterized protein. (172 aa)
	ppp1r9a	Protein phosphatase 1, regulatory subunit 9A. (1142 aa)
	kcnd1	Potassium voltage-gated channel, Shal-related subfamily, member 1; Belongs to the potassium channel family. (638 aa)
	LOC102306328	Shisa family member 7. (673 aa)
	abr	ABR activator of RhoGEF and GTPase. (763 aa)
	shisa8	Shisa family member 8b. (471 aa)
	LOC102310016	Nuclear receptor subfamily 1, group D, member 4b. (587 aa)
	gpm6a	Glycoprotein M6Aa. (278 aa)
	LOC102292921	BCR activator of RhoGEF and GTPase. (1382 aa)
	shisa9	Shisa family member 9a. (563 aa)
	GPM6A	Glycoprotein M6Ab. (278 aa)
	gper1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	LOC102309694	Uncharacterized protein. (1720 aa)
	LOC102313511	Cytoplasmic polyadenylation element binding protein 4a. (730 aa)
	LOC102293948	Nerve growth factor receptor b. (429 aa)
	ENSHBUP00000024105	SH3 domain-containing protein. (89 aa)
	als2	Alsin Rho guanine nucleotide exchange factor ALS2 b. (1687 aa)
	srgap2	SLIT-ROBO Rho GTPase activating protein 2. (1124 aa)
	LOC102311613	Cell division cycle 42. (191 aa)
	TANC2	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2. (2127 aa)
	LOC102294639	Uncharacterized protein. (155 aa)
	KCND3	Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (634 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (838 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (765 aa)
	LOC102291233	Glutamate ionotropic receptor AMPA type subunit 3. (882 aa)
	LOC102306271	Amyloid beta (A4) precursor protein-binding, family A, member 1b. (1149 aa)
	fmr1	Fragile X mental retardation 1. (600 aa)
	ptk2b	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (989 aa)
	LOC102310947	Shisa family member 7a. (706 aa)
	LOC102313079	Amyloid beta precursor protein binding family A member 3. (719 aa)
	LOC102309827	Paralemmin 1b. (245 aa)
	LOC102293489	Uncharacterized protein. (295 aa)
	LOC102307526	Uncharacterized protein. (191 aa)
	LOC102307627	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (894 aa)
	LOC102296347	PDZ domain-containing protein. (876 aa)
	LOC102312812	Uncharacterized protein. (572 aa)
	LOC102314603	Uncharacterized protein. (184 aa)
	LOC102294332	Protein phosphatase 1 regulatory subunit 9A-like A. (1448 aa)
	LOC102288514	Peptidase_S9 domain-containing protein. (360 aa)
	LOC102294714	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (956 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSHBUP00000003545	ENSHBUP00000007818	ENSHBUP00000003545	Cell division cycle 42.	Uncharacterized protein.	0.766
CDC42	ENSHBUP00000008174	ENSHBUP00000007818	ENSHBUP00000008174	Cell division cycle 42.	SAM domain-containing protein.	0.766
CDC42	ENSHBUP00000012612	ENSHBUP00000007818	ENSHBUP00000012612	Cell division cycle 42.	SH3 and multiple ankyrin repeat domains 2a.	0.547
CDC42	ENSHBUP00000012616	ENSHBUP00000007818	ENSHBUP00000012616	Cell division cycle 42.	Uncharacterized protein.	0.766
CDC42	ENSHBUP00000024105	ENSHBUP00000007818	ENSHBUP00000024105	Cell division cycle 42.	SH3 domain-containing protein.	0.647
CDC42	LOC102288700	ENSHBUP00000007818	ENSHBUP00000016530	Cell division cycle 42.	Uncharacterized protein.	0.528
CDC42	LOC102292921	ENSHBUP00000007818	ENSHBUP00000021557	Cell division cycle 42.	BCR activator of RhoGEF and GTPase.	0.656
CDC42	LOC102294469	ENSHBUP00000007818	ENSHBUP00000011761	Cell division cycle 42.	Uncharacterized protein.	0.523
CDC42	LOC102294714	ENSHBUP00000007818	ENSHBUP00000035318	Cell division cycle 42.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.613
CDC42	LOC102300760	ENSHBUP00000007818	ENSHBUP00000002551	Cell division cycle 42.	BAI1-associated protein 2a.	0.940
CDC42	LOC102305737	ENSHBUP00000007818	ENSHBUP00000001484	Cell division cycle 42.	Uncharacterized protein.	0.575
CDC42	LOC102307526	ENSHBUP00000007818	ENSHBUP00000030785	Cell division cycle 42.	Uncharacterized protein.	0.523
CDC42	LOC102307627	ENSHBUP00000007818	ENSHBUP00000030791	Cell division cycle 42.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.613
CDC42	LOC102309694	ENSHBUP00000007818	ENSHBUP00000023000	Cell division cycle 42.	Uncharacterized protein.	0.766
CDC42	LOC102314603	ENSHBUP00000007818	ENSHBUP00000032301	Cell division cycle 42.	Uncharacterized protein.	0.531
CDC42	abr	ENSHBUP00000007818	ENSHBUP00000018855	Cell division cycle 42.	ABR activator of RhoGEF and GTPase.	0.656
CDC42	als2	ENSHBUP00000007818	ENSHBUP00000024258	Cell division cycle 42.	Alsin Rho guanine nucleotide exchange factor ALS2 b.	0.575
CDC42	baiap2	ENSHBUP00000007818	ENSHBUP00000001304	Cell division cycle 42.	BAI1 associated protein 2.	0.940
CDC42	bcr	ENSHBUP00000007818	ENSHBUP00000000407	Cell division cycle 42.	Si:dkey-91m11.5.	0.656
CDC42	dock10	ENSHBUP00000007818	ENSHBUP00000016250	Cell division cycle 42.	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.954