STRINGSTRING
LOC102289726 LOC102289726 fzd8 fzd8 LOC102296557 LOC102296557 ENSHBUP00000001260 ENSHBUP00000001260 LOC102314283 LOC102314283 map3k13 map3k13 axin1 axin1 LOC102299736 LOC102299736 ENSHBUP00000002232 ENSHBUP00000002232 map2k7 map2k7 pik3r5 pik3r5 LOC102314677 LOC102314677 LOC102294502 LOC102294502 pdcd10 pdcd10 htr2b htr2b il34 il34 pdgfb pdgfb LOC102314301 LOC102314301 pdgfa pdgfa map3k4 map3k4 sash1 sash1 LOC102308448 LOC102308448 LOC102309602 LOC102309602 LOC102302149 LOC102302149 map2k5 map2k5 LOC102307308 LOC102307308 fzd4 fzd4 vegfa vegfa tnfsf11 tnfsf11 tpd52l1 tpd52l1 ntf3 ntf3 fzd5 fzd5 ENSHBUP00000015748 ENSHBUP00000015748 ENSHBUP00000016426 ENSHBUP00000016426 LOC102310436 LOC102310436 fgf2 fgf2 p2rx7 p2rx7 LOC102291272 LOC102291272 PIK3R5 PIK3R5 LOC102304742 LOC102304742 LOC102305789 LOC102305789 LOC102310023 LOC102310023 pdgfc pdgfc dusp19 dusp19 LOC102288611 LOC102288611 map3k7 map3k7 LOC102304734 LOC102304734 LOC102296736 LOC102296736 LOC102304962 LOC102304962 fgf18 fgf18 LOC102288968 LOC102288968 ern1 ern1 nek10 nek10 LOC102289294 LOC102289294 nox4 nox4 drd4 drd4 lrrk2 lrrk2 pik3cg pik3cg edn1 edn1 LOC102292960 LOC102292960 LOC102293702 LOC102293702 LOC102289510 LOC102289510 LOC102292008 LOC102292008 ajuba ajuba
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102289726Uncharacterized protein. (203 aa)
fzd8Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (563 aa)
LOC102296557Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
ENSHBUP00000001260G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (324 aa)
LOC102314283Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
map3k13Mitogen-activated protein kinase kinase kinase. (1008 aa)
axin1Axin 1. (825 aa)
LOC102299736Interleukin-1. (114 aa)
ENSHBUP00000002232Uncharacterized protein. (176 aa)
map2k7Mitogen-activated protein kinase kinase 7. (453 aa)
pik3r5Phosphoinositide-3-kinase, regulatory subunit 5. (850 aa)
LOC102314677Protein kinase domain-containing protein. (354 aa)
LOC102294502Uncharacterized protein. (772 aa)
pdcd10Programmed cell death 10a. (198 aa)
htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (478 aa)
il34Interleukin 34. (257 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (549 aa)
LOC102314301Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (206 aa)
pdgfaPlatelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (230 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1486 aa)
sash1SAM and SH3 domain containing 1a. (1382 aa)
LOC102308448Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
LOC102309602Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
LOC102302149Uncharacterized protein. (827 aa)
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (438 aa)
LOC102307308SAM and SH3 domain containing 1b. (1092 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
tnfsf11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (265 aa)
tpd52l1Tpd52 like 1. (279 aa)
ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (293 aa)
fzd5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
ENSHBUP00000015748PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (129 aa)
ENSHBUP00000016426Protein kinase domain-containing protein. (84 aa)
LOC102310436Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (580 aa)
LOC102291272Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1095 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (854 aa)
LOC102304742Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
LOC102305789Transforming growth factor, alpha. (254 aa)
LOC102310023Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (515 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (364 aa)
dusp19Dual specificity phosphatase 19a. (208 aa)
LOC102288611Teneurin transmembrane protein 1. (2761 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (510 aa)
LOC102304734CD40 molecule, TNF receptor superfamily member 5. (308 aa)
LOC102296736G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (414 aa)
LOC102304962Programmed cell death 10b. (210 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC102288968Epithelial mitogen homolog (mouse). (164 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1077 aa)
nek10NIMA-related kinase 10. (1060 aa)
LOC102289294Fibroblast growth factor receptor. (836 aa)
nox4FAD-binding FR-type domain-containing protein. (497 aa)
drd4Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (402 aa)
lrrk2Leucine-rich repeat kinase 2. (2426 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1122 aa)
edn1Endothelin 1. (201 aa)
LOC102292960Uncharacterized protein. (844 aa)
LOC102293702Dickkopf WNT signaling pathway inhibitor 1a. (253 aa)
LOC102289510Endoplasmic reticulum to nucleus signaling 2. (979 aa)
LOC102292008Uncharacterized protein. (458 aa)
ajubaAjuba LIM protein. (733 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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