68 items (Haplochromis burtoni) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102289257	Wolfram syndrome 1a (wolframin). (1062 aa)
	psenen	Presenilin enhancer, gamma-secretase subunit. (101 aa)
	LOC102288586	Forkhead box Q1a. (273 aa)
	LOC102292695	G_PROTEIN_RECEP_F1_2 domain-containing protein. (271 aa)
	lig4	DNA ligase. (910 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1147 aa)
	ENSHBUP00000005472	Uncharacterized protein. (330 aa)
	nfatc4	Nuclear factor of activated T cells 4. (849 aa)
	vps54	VPS54 subunit of GARP complex. (986 aa)
	gclm	Glutamate-cysteine ligase, modifier subunit. (277 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1063 aa)
	LOC102306795	J domain-containing protein. (197 aa)
	wfs1	Wolfram syndrome 1b (wolframin). (922 aa)
	ENSHBUP00000009061	GRANULINS domain-containing protein. (138 aa)
	unc5b	Unc-5 netrin receptor B. (945 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (432 aa)
	LOC102292190	DnaJ (Hsp40) homolog, subfamily C, member 5ab. (216 aa)
	lgmn	Legumain. (429 aa)
	LOC102290252	JunE proto-oncogene, AP-1 transcription factor subunit. (347 aa)
	LOC102311825	Homeobox protein engrailed-like. (284 aa)
	nrbp2	Nuclear receptor binding protein 2b. (505 aa)
	thap11	THAP domain containing 11. (276 aa)
	ntf3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (293 aa)
	LOC102313643	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (428 aa)
	ENSHBUP00000016109	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (261 aa)
	gdnf	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (257 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	ENSHBUP00000017560	Uncharacterized protein. (101 aa)
	ENSHBUP00000017574	GRANULINS domain-containing protein. (54 aa)
	LOC102289199	Uncharacterized protein. (206 aa)
	LOC102288884	Uncharacterized protein. (205 aa)
	ENSHBUP00000017602	Uncharacterized protein. (207 aa)
	LOC102310207	Homeobox protein engrailed-like. (292 aa)
	adnp	Activity-dependent neuroprotector homeobox b. (1057 aa)
	dnajc5g	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a. (221 aa)
	LOC102310411	V-set and transmembrane domain containing 2 like. (193 aa)
	ndnf	Neuron-derived neurotrophic factor. (569 aa)
	gper1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	LOC102313511	Cytoplasmic polyadenylation element binding protein 4a. (730 aa)
	F2R	G_PROTEIN_RECEP_F1_2 domain-containing protein. (381 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	ENSHBUP00000024930	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (147 aa)
	pink1	PTEN induced kinase 1. (574 aa)
	ENSHBUP00000024997	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (292 aa)
	LOC102293267	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (362 aa)
	kif14	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1615 aa)
	il6st	Uncharacterized protein. (894 aa)
	yju2	YJU2 splicing factor homolog. (340 aa)
	xrcc2	X-ray repair cross complementing 2. (324 aa)
	LOC102304895	DnaJ (Hsp40) homolog, subfamily C, member 5aa. (199 aa)
	cited1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (153 aa)
	LOC102297012	CCAAT enhancer binding protein beta. (292 aa)
	LOC102295896	Ig-like domain-containing protein. (267 aa)
	ENSHBUP00000029217	ZPR1 zinc finger. (452 aa)
	ptprz1	Protein tyrosine phosphatase receptor type Z1b. (1271 aa)
	LOC102297117	Cytokine receptor-like factor 1a. (397 aa)
	ENSHBUP00000033650	MBD domain-containing protein. (177 aa)
	LOC102293187	J domain-containing protein. (221 aa)
	HDGF	Heparin binding growth factor. (239 aa)
	LOC102290331	Baculoviral IAP repeat containing 5a. (142 aa)
	ENSHBUP00000034837	Forkhead box Q1b. (275 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1001 aa)
	ppt1	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (303 aa)
	LOC102297268	Uncharacterized protein. (204 aa)
	grn	Granulin b. (828 aa)
	sncb	Beta-synuclein; Belongs to the synuclein family. (117 aa)
	LOC102309754	Cytokine receptor-like factor 1b. (468 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1283 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000005472	gdnf	ENSHBUP00000005472	ENSHBUP00000016840	Uncharacterized protein.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.924
ENSHBUP00000016109	ENSHBUP00000024997	ENSHBUP00000016109	ENSHBUP00000024997	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	0.400
ENSHBUP00000016109	LOC102293267	ENSHBUP00000016109	ENSHBUP00000025068	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.400
ENSHBUP00000016109	LOC102297012	ENSHBUP00000016109	ENSHBUP00000028547	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	CCAAT enhancer binding protein beta.	0.605
ENSHBUP00000016109	LOC102313643	ENSHBUP00000016109	ENSHBUP00000015836	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.400
ENSHBUP00000016109	gdnf	ENSHBUP00000016109	ENSHBUP00000016840	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.465
ENSHBUP00000024930	gdnf	ENSHBUP00000024930	ENSHBUP00000016840	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.552
ENSHBUP00000024930	ntf3	ENSHBUP00000024930	ENSHBUP00000014557	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.	0.432
ENSHBUP00000024997	ENSHBUP00000016109	ENSHBUP00000024997	ENSHBUP00000016109	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.400
ENSHBUP00000024997	LOC102290252	ENSHBUP00000024997	ENSHBUP00000013178	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	JunE proto-oncogene, AP-1 transcription factor subunit.	0.400
ENSHBUP00000024997	LOC102313643	ENSHBUP00000024997	ENSHBUP00000015836	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.658
ENSHBUP00000033650	ppt1	ENSHBUP00000033650	ENSHBUP00000000454	MBD domain-containing protein.	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).	0.563
LOC102289257	wfs1	ENSHBUP00000032139	ENSHBUP00000008437	Wolfram syndrome 1a (wolframin).	Wolfram syndrome 1b (wolframin).	0.832
LOC102290252	ENSHBUP00000024997	ENSHBUP00000013178	ENSHBUP00000024997	JunE proto-oncogene, AP-1 transcription factor subunit.	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	0.400
LOC102290252	LOC102293267	ENSHBUP00000013178	ENSHBUP00000025068	JunE proto-oncogene, AP-1 transcription factor subunit.	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.400
LOC102290252	LOC102297012	ENSHBUP00000013178	ENSHBUP00000028547	JunE proto-oncogene, AP-1 transcription factor subunit.	CCAAT enhancer binding protein beta.	0.605
LOC102290252	LOC102313643	ENSHBUP00000013178	ENSHBUP00000015836	JunE proto-oncogene, AP-1 transcription factor subunit.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.400
LOC102290252	gdnf	ENSHBUP00000013178	ENSHBUP00000016840	JunE proto-oncogene, AP-1 transcription factor subunit.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.465
LOC102290331	kif14	ENSHBUP00000034386	ENSHBUP00000025157	Baculoviral IAP repeat containing 5a.	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.490
LOC102292190	ppargc1a	ENSHBUP00000011156	ENSHBUP00000003949	DnaJ (Hsp40) homolog, subfamily C, member 5ab.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.514