STRINGSTRING
LOC102293018 LOC102293018 anapc7 anapc7 LOC102288638 LOC102288638 LOC102313764 LOC102313764 cdc7 cdc7 LOC102303825 LOC102303825 pole pole LOC102296686 LOC102296686 LOC102294511 LOC102294511 LOC102309509 LOC102309509 LOC102298085 LOC102298085 CDC25B CDC25B lats1 lats1 foxm1 foxm1 ARPP19 ARPP19 LOC102290810 LOC102290810 ccnb1 ccnb1 e2f1 e2f1 ccnd1 ccnd1 ccnb2 ccnb2 ENSHBUP00000029217 ENSHBUP00000029217 ENSHBUP00000030388 ENSHBUP00000030388 chek1 chek1 ccni ccni CKS2 CKS2 ENSHBUP00000032172 ENSHBUP00000032172 fbxl6 fbxl6 ENSHBUP00000032420 ENSHBUP00000032420 sirt7 sirt7 brsk1 brsk1 anapc2 anapc2 ccna2 ccna2 LOC102306622 LOC102306622 LOC102301826 LOC102301826 ube2l3 ube2l3 ENSHBUP00000033958 ENSHBUP00000033958 ccne1 ccne1 LOC102311132 LOC102311132 ENSHBUP00000034358 ENSHBUP00000034358 LOC102297558 LOC102297558 usp37 usp37 cdk14 cdk14 hinfp hinfp skp2 skp2 ppm1d ppm1d anapc1 anapc1 ENSHBUP00000023745 ENSHBUP00000023745 timeless timeless cdk4 cdk4 ccnj ccnj lats2 lats2 nasp nasp LOC102289636 LOC102289636 rb1 rb1 plk3 plk3 LOC102311736 LOC102311736 clasp1 clasp1 mnat1 mnat1 ccnb3 ccnb3 cdk15 cdk15 cntd2 cntd2 LOC102289693 LOC102289693 cdc23 cdc23 LOC102312959 LOC102312959 rcc1 rcc1 chek2 chek2 cdk6 cdk6 trim71 trim71 fbxl15 fbxl15 ENSHBUP00000016698 ENSHBUP00000016698 LOC102313340 LOC102313340 clasp2 clasp2 ppp2r2d ppp2r2d LOC102302005 LOC102302005 bub1b bub1b PLK1 PLK1 cdc27 cdc27 mastl mastl tpd52l1 tpd52l1 LOC102291346 LOC102291346 NASP NASP cdk1 cdk1 fbxl22 fbxl22 LOC102308881 LOC102308881 ube2s ube2s chmp7 chmp7 LOC102299917 LOC102299917 e2f7 e2f7 LOC102291342 LOC102291342 LOC102314217 LOC102314217 CCNO CCNO spdya spdya FOXM1 FOXM1 cdc16 cdc16 plk2 plk2 cacul1 cacul1 LOC102294243 LOC102294243 LOC102304830 LOC102304830 ube2c ube2c cdk5 cdk5 LOC102303495 LOC102303495 LOC102289972 LOC102289972 CCNG2 CCNG2 LOC102296287 LOC102296287 ccnf ccnf fbxl12 fbxl12 LOC102312715 LOC102312715 ccna1 ccna1 npat npat LOC102294096 LOC102294096 cdk17 cdk17 LOC102298603 LOC102298603 cdk2 cdk2 chmp2a chmp2a LOC102302651 LOC102302651 LOC102294502 LOC102294502 kdm8 kdm8 PPP6C PPP6C ccnd3 ccnd3 LOC102310375 LOC102310375
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102293018cAMP-regulated phosphoprotein 19b; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (116 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
LOC102288638Cyclin J-like; Belongs to the cyclin family. (417 aa)
LOC102313764Serine/threonine-protein phosphatase. (337 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (611 aa)
LOC102303825Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (300 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2016 aa)
LOC102296686Protein kinase domain-containing protein. (549 aa)
LOC102294511Si:dkey-16p21.7. (749 aa)
LOC102309509E2F transcription factor 5. (385 aa)
LOC102298085Cyclin Dx; Belongs to the cyclin family. (317 aa)
CDC25BCell division cycle 25B. (571 aa)
lats1Large tumor suppressor kinase 1. (1048 aa)
foxm1Forkhead box M1. (630 aa)
ARPP19cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (112 aa)
LOC102290810Uncharacterized protein. (1433 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (402 aa)
e2f1E2F transcription factor 1. (454 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
ccnb2Cyclin B2; Belongs to the cyclin family. (388 aa)
ENSHBUP00000029217ZPR1 zinc finger. (452 aa)
ENSHBUP00000030388AAA domain-containing protein; Belongs to the AAA ATPase family. (284 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (460 aa)
ccniCyclin I; Belongs to the cyclin family. (425 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (60 aa)
ENSHBUP00000032172Uncharacterized protein. (108 aa)
fbxl6F-box domain-containing protein. (565 aa)
ENSHBUP00000032420FCP1 homology domain-containing protein. (278 aa)
sirt7Sirtuin 7. (405 aa)
brsk1Protein kinase domain-containing protein. (748 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (646 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (434 aa)
LOC102306622Protein phosphatase, Mg2+/Mn2+ dependent, 1Db. (572 aa)
LOC102301826Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (93 aa)
ube2l3Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
ENSHBUP00000033958TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (229 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (462 aa)
LOC102311132Cyclin I family, member 2; Belongs to the cyclin family. (364 aa)
ENSHBUP00000034358Vps4_C domain-containing protein. (151 aa)
LOC102297558Citron rho-interacting serine/threonine kinase a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1961 aa)
usp37Ubiquitin carboxyl-terminal hydrolase. (958 aa)
cdk14Cyclin-dependent kinase 14; Belongs to the protein kinase superfamily. (470 aa)
hinfpHistone H4 transcription factor. (492 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (416 aa)
ppm1dProtein phosphatase, Mg2+/Mn2+ dependent, 1Da. (557 aa)
anapc1Anaphase promoting complex subunit 1. (1982 aa)
ENSHBUP00000023745Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
timelessTimeless circadian clock. (1249 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (318 aa)
ccnjCyclin J; Belongs to the cyclin family. (354 aa)
lats2Large tumor suppressor kinase 2. (1173 aa)
naspNuclear autoantigenic sperm protein (histone-binding). (425 aa)
LOC102289636Zgc:112083. (509 aa)
rb1Retinoblastoma 1. (912 aa)
plk3Serine/threonine-protein kinase PLK. (677 aa)
LOC102311736Citron rho-interacting serine/threonine kinase b. (1618 aa)
clasp1Cytoplasmic linker associated protein 1a. (1430 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (408 aa)
cdk15Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (381 aa)
cntd2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (361 aa)
LOC102289693G protein-coupled receptor 132a; Belongs to the G-protein coupled receptor 1 family. (354 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
LOC102312959Cyclin-dependent kinase 16. (440 aa)
rcc1Regulator of chromosome condensation 1. (418 aa)
chek2Checkpoint kinase 2. (521 aa)
cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa)
trim71Tripartite motif containing 71, E3 ubiquitin protein ligase. (837 aa)
fbxl15F-box and leucine-rich repeat protein 15. (292 aa)
ENSHBUP00000016698FCP1_C domain-containing protein. (180 aa)
LOC102313340Cyclin E2; Belongs to the cyclin family. (391 aa)
clasp2Cytoplasmic linker associated protein 2. (1208 aa)
ppp2r2dSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
LOC102302005Cyclin G2; Belongs to the cyclin family. (334 aa)
bub1bBUB1 mitotic checkpoint serine/threonine kinase Bb. (426 aa)
PLK1Serine/threonine-protein kinase PLK. (582 aa)
cdc27Cell division cycle 27. (802 aa)
mastlMicrotubule associated serine/threonine kinase-like. (846 aa)
tpd52l1Tpd52 like 1. (279 aa)
LOC102291346Endosulfine alpha a; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (169 aa)
NASPNuclear autoantigenic sperm protein. (409 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (307 aa)
fbxl22F-box and leucine-rich repeat protein 22. (228 aa)
LOC102308881Leucine zipper, putative tumor suppressor 1. (671 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (233 aa)
chmp7Charged multivesicular body protein 7. (450 aa)
LOC102299917Cyclin D2, a; Belongs to the cyclin family. (297 aa)
e2f7E2F transcription factor 7. (793 aa)
LOC102291342Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (222 aa)
LOC102314217Protein kinase domain-containing protein. (866 aa)
CCNOCyclin O; Belongs to the cyclin family. (361 aa)
spdyaSpeedy/RINGO cell cycle regulator family member A. (266 aa)
FOXM1Forkhead box M1. (637 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
plk2Polo-like kinase 2b (Drosophila). (589 aa)
cacul1CDK2 associated cullin domain 1; Belongs to the cullin family. (339 aa)
LOC102294243Cyclin D2, b; Belongs to the cyclin family. (294 aa)
LOC102304830Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
LOC102303495Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (222 aa)
LOC102289972Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (355 aa)
LOC102296287Cyclin dependent kinase 17; Belongs to the protein kinase superfamily. (430 aa)
ccnfCyclin F; Belongs to the cyclin family. (785 aa)
fbxl12F-box domain-containing protein. (406 aa)
LOC102312715Usher syndrome 1C. (523 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (398 aa)
npatUncharacterized protein. (1312 aa)
LOC102294096Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (294 aa)
cdk17Cyclin dependent kinase 17. (523 aa)
LOC102298603Protein kinase domain-containing protein. (682 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
chmp2aCharged multivesicular body protein 2A. (220 aa)
LOC102302651Si:ch211-195d17.2. (392 aa)
LOC102294502Uncharacterized protein. (772 aa)
kdm8Lysine (K)-specific demethylase 8. (408 aa)
PPP6CSerine/threonine-protein phosphatase. (305 aa)
ccnd3Cyclin D3; Belongs to the cyclin family. (311 aa)
LOC102310375Cyclin dependent kinase 18; Belongs to the protein kinase superfamily. (443 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.