(54 nodes) Intermediate filament cytoskeleton organization network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cln8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	NEFL	Neurofilament light; Belongs to the intermediate filament family. (536 aa)
	nefm	Neurofilament, medium polypeptide a; Belongs to the intermediate filament family. (949 aa)
	klhl24	Kelch-like family member 24a. (600 aa)
	ENSHBUP00000035003	Uncharacterized protein. (665 aa)
	BFSP1	Beaded filament structural protein 1; Belongs to the intermediate filament family. (679 aa)
	LOC102308480	Keratin 15; Belongs to the intermediate filament family. (450 aa)
	LOC102305638	Plectin a. (4587 aa)
	ENSHBUP00000032022	S10_plectin domain-containing protein. (172 aa)
	LOC102296717	Synemin, intermediate filament protein; Belongs to the intermediate filament family. (1024 aa)
	macf1	Microtubule actin crosslinking factor 1. (5054 aa)
	pkp2	Uncharacterized protein. (787 aa)
	nefl	Neurofilament, light polypeptide b; Belongs to the intermediate filament family. (597 aa)
	LOC102292455	IF rod domain-containing protein; Belongs to the intermediate filament family. (428 aa)
	LOC102314543	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (451 aa)
	LOC102295920	NudE neurodevelopment protein 1-like 1a. (343 aa)
	LOC102299224	Desmin a; Belongs to the intermediate filament family. (475 aa)
	ENSHBUP00000021429	S10_plectin domain-containing protein. (166 aa)
	LOC102310094	Zgc:158846; Belongs to the intermediate filament family. (560 aa)
	LOC102309789	Keratin 4; Belongs to the intermediate filament family. (447 aa)
	LOC102289436	Wu:fi04e12. (2079 aa)
	LOC102303747	Envoplakin b. (2037 aa)
	LOC102302333	Internexin neuronal intermediate filament protein, alpha b; Belongs to the intermediate filament family. (481 aa)
	LOC102299158	IF rod domain-containing protein; Belongs to the intermediate filament family. (450 aa)
	LOC102307626	Si:ch211-156l18.7; Belongs to the intermediate filament family. (409 aa)
	LOC102307953	Keratin 98; Belongs to the intermediate filament family. (438 aa)
	LOC102304657	IF rod domain-containing protein; Belongs to the intermediate filament family. (451 aa)
	LOC102304960	IF rod domain-containing protein; Belongs to the intermediate filament family. (411 aa)
	LOC102288489	Notochord granular surface; Belongs to the intermediate filament family. (523 aa)
	LOC102292148	IF rod domain-containing protein; Belongs to the intermediate filament family. (434 aa)
	LOC102310829	IF rod domain-containing protein; Belongs to the intermediate filament family. (517 aa)
	vim	Vimentin like; Belongs to the intermediate filament family. (455 aa)
	des	Desmin b; Belongs to the intermediate filament family. (470 aa)
	nefh	IF rod domain-containing protein; Belongs to the intermediate filament family. (708 aa)
	bfsp2	Beaded filament structural protein 2, phakinin; Belongs to the intermediate filament family. (432 aa)
	vps54	VPS54 subunit of GARP complex. (986 aa)
	agfg1	ArfGAP with FG repeats 1a. (585 aa)
	ENSHBUP00000006119	SH3 domain-containing protein. (1089 aa)
	DST	Dystonin. (3889 aa)
	LOC102292621	ArfGAP with FG repeats 1b. (472 aa)
	PKP1	Plakophilin 1. (702 aa)
	ppl	Periplakin. (1761 aa)
	dsp	Desmoplakin a. (2709 aa)
	LOC102292551	Keratin 18a, tandem duplicate 1; Belongs to the intermediate filament family. (436 aa)
	LOC102292851	Keratin 8; Belongs to the intermediate filament family. (510 aa)
	LOC102293351	Keratin 5; Belongs to the intermediate filament family. (538 aa)
	prph	Peripherin; Belongs to the intermediate filament family. (492 aa)
	ENSHBUP00000003165	Uncharacterized protein. (236 aa)
	ENSHBUP00000003154	Uncharacterized protein. (337 aa)
	LOC102294619	NudE neurodevelopment protein 1-like 1b. (340 aa)
	LOC102290985	Plectin b. (4551 aa)
	evpl	Envoplakin a. (2002 aa)
	KRT222	Keratin 222; Belongs to the intermediate filament family. (540 aa)
	LOC102292943	Keratin 97; Belongs to the intermediate filament family. (502 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BFSP1	bfsp2	ENSHBUP00000033207	ENSHBUP00000008015	Beaded filament structural protein 1; Belongs to the intermediate filament family.	Beaded filament structural protein 2, phakinin; Belongs to the intermediate filament family.	0.720
DST	ENSHBUP00000006119	ENSHBUP00000005667	ENSHBUP00000006119	Dystonin.	SH3 domain-containing protein.	0.917
DST	PKP1	ENSHBUP00000005667	ENSHBUP00000004883	Dystonin.	Plakophilin 1.	0.571
DST	pkp2	ENSHBUP00000005667	ENSHBUP00000030686	Dystonin.	Uncharacterized protein.	0.570
ENSHBUP00000003154	PKP1	ENSHBUP00000003154	ENSHBUP00000004883	Uncharacterized protein.	Plakophilin 1.	0.550
ENSHBUP00000003154	pkp2	ENSHBUP00000003154	ENSHBUP00000030686	Uncharacterized protein.	Uncharacterized protein.	0.550
ENSHBUP00000003165	PKP1	ENSHBUP00000003165	ENSHBUP00000004883	Uncharacterized protein.	Plakophilin 1.	0.550
ENSHBUP00000003165	pkp2	ENSHBUP00000003165	ENSHBUP00000030686	Uncharacterized protein.	Uncharacterized protein.	0.550
ENSHBUP00000006119	DST	ENSHBUP00000006119	ENSHBUP00000005667	SH3 domain-containing protein.	Dystonin.	0.917
ENSHBUP00000006119	ENSHBUP00000035003	ENSHBUP00000006119	ENSHBUP00000035003	SH3 domain-containing protein.	Uncharacterized protein.	0.885
ENSHBUP00000006119	PKP1	ENSHBUP00000006119	ENSHBUP00000004883	SH3 domain-containing protein.	Plakophilin 1.	0.570
ENSHBUP00000006119	pkp2	ENSHBUP00000006119	ENSHBUP00000030686	SH3 domain-containing protein.	Uncharacterized protein.	0.570
ENSHBUP00000021429	ENSHBUP00000035003	ENSHBUP00000021429	ENSHBUP00000035003	S10_plectin domain-containing protein.	Uncharacterized protein.	0.873
ENSHBUP00000021429	LOC102290985	ENSHBUP00000021429	ENSHBUP00000002956	S10_plectin domain-containing protein.	Plectin b.	0.820
ENSHBUP00000021429	LOC102305638	ENSHBUP00000021429	ENSHBUP00000032155	S10_plectin domain-containing protein.	Plectin a.	0.803
ENSHBUP00000021429	PKP1	ENSHBUP00000021429	ENSHBUP00000004883	S10_plectin domain-containing protein.	Plakophilin 1.	0.570
ENSHBUP00000021429	pkp2	ENSHBUP00000021429	ENSHBUP00000030686	S10_plectin domain-containing protein.	Uncharacterized protein.	0.570
ENSHBUP00000032022	LOC102290985	ENSHBUP00000032022	ENSHBUP00000002956	S10_plectin domain-containing protein.	Plectin b.	0.578
ENSHBUP00000032022	LOC102305638	ENSHBUP00000032022	ENSHBUP00000032155	S10_plectin domain-containing protein.	Plectin a.	0.613
ENSHBUP00000032022	PKP1	ENSHBUP00000032022	ENSHBUP00000004883	S10_plectin domain-containing protein.	Plakophilin 1.	0.468