(53 nodes) Fat cell differentiation network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102306757	E1A binding protein p300 a. (2600 aa)
	prdm16	Si:ch211-263k4.2. (1305 aa)
	LOC102303727	Activating transcription factor 5a. (505 aa)
	ffar4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (226 aa)
	dhrs7b	Dehydrogenase/reductase (SDR family) member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
	bbs4	Bardet-Biedl syndrome 4. (545 aa)
	ttc8	Tetratricopeptide repeat domain 8. (505 aa)
	LOC102294806	Aldedh domain-containing protein. (546 aa)
	LOC102311721	Uncharacterized protein. (1190 aa)
	steap4	STEAP4 metalloreductase. (472 aa)
	nr4a3	Nuclear receptor subfamily 4, group A, member 3. (681 aa)
	LOC102299510	STEAP family member 4. (448 aa)
	bbs9	Bardet-Biedl syndrome 9. (995 aa)
	LOC106633175	LRRCT domain-containing protein. (334 aa)
	bscl2	Uncharacterized protein. (357 aa)
	LOC102297012	CCAAT enhancer binding protein beta. (292 aa)
	LOC102306039	Transmembrane protein 120A. (352 aa)
	FFAR2	G_PROTEIN_RECEP_F1_2 domain-containing protein. (335 aa)
	ENSHBUP00000027387	NR LBD domain-containing protein. (214 aa)
	cebpd	CCAAT/enhancer-binding protein. (265 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (620 aa)
	LOC102305861	Nuclear receptor subfamily 4, group A, member 1. (575 aa)
	LOC102308982	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (448 aa)
	ENSHBUP00000021923	Uncharacterized protein. (845 aa)
	cntn2	Contactin 2. (977 aa)
	lamb3	Uncharacterized protein. (1158 aa)
	ctbp1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (461 aa)
	nhlrc4	Tripartite motif containing 32. (693 aa)
	mkks	McKusick-Kaufman syndrome. (565 aa)
	bbs1	Bardet-Biedl syndrome 1. (583 aa)
	bbs12	Bardet-Biedl syndrome 12. (634 aa)
	LOC102303264	Transmembrane protein 120B. (347 aa)
	aldh6a1	Aldehyde dehydrogenase 6 family member A1. (544 aa)
	bbs7	Bardet-Biedl syndrome 7. (712 aa)
	LOC102290675	Uncharacterized protein. (1034 aa)
	LOC102303679	Activating transcription factor 5b. (532 aa)
	fam120b	Family with sequence similarity 120B. (748 aa)
	ep300	E1A binding protein p300 b. (2764 aa)
	socs1	Suppressor of cytokine signaling 1a. (215 aa)
	med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1838 aa)
	tmem120a	Zgc:103681. (340 aa)
	LOC102290481	Uncharacterized protein. (332 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (715 aa)
	ENSHBUP00000009033	Nuclear receptor domain-containing protein. (120 aa)
	ZNF516	Zinc finger protein 516. (1104 aa)
	LOC102290185	BSCL2 lipid droplet biogenesis associated, seipin. (421 aa)
	ENSHBUP00000004641	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (501 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (592 aa)
	adrb1	Adrenoceptor beta 1. (397 aa)
	LOC102294801	Adrenoceptor beta 2, surface a; Belongs to the G-protein coupled receptor 1 family. (417 aa)
	nr4a2	Nuclear receptor subfamily 4, group A, member 2b. (600 aa)
	hmga2	Uncharacterized protein. (114 aa)
	ENSHBUP00000000302	Uncharacterized protein. (79 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000009033	ENSHBUP00000027387	ENSHBUP00000009033	ENSHBUP00000027387	Nuclear receptor domain-containing protein.	NR LBD domain-containing protein.	0.866
ENSHBUP00000009033	LOC102306757	ENSHBUP00000009033	ENSHBUP00000020755	Nuclear receptor domain-containing protein.	E1A binding protein p300 a.	0.407
ENSHBUP00000009033	ep300	ENSHBUP00000009033	ENSHBUP00000015535	Nuclear receptor domain-containing protein.	E1A binding protein p300 b.	0.407
ENSHBUP00000009033	med1	ENSHBUP00000009033	ENSHBUP00000013910	Nuclear receptor domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.570
ENSHBUP00000021923	LOC102290675	ENSHBUP00000021923	ENSHBUP00000017367	Uncharacterized protein.	Uncharacterized protein.	0.576
ENSHBUP00000021923	LOC102306757	ENSHBUP00000021923	ENSHBUP00000020755	Uncharacterized protein.	E1A binding protein p300 a.	0.415
ENSHBUP00000021923	LOC102308982	ENSHBUP00000021923	ENSHBUP00000022261	Uncharacterized protein.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.576
ENSHBUP00000021923	LOC102311721	ENSHBUP00000021923	ENSHBUP00000031409	Uncharacterized protein.	Uncharacterized protein.	0.576
ENSHBUP00000021923	ctbp1	ENSHBUP00000021923	ENSHBUP00000021447	Uncharacterized protein.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.576
ENSHBUP00000021923	ep300	ENSHBUP00000021923	ENSHBUP00000015535	Uncharacterized protein.	E1A binding protein p300 b.	0.415
ENSHBUP00000021923	prdm16	ENSHBUP00000021923	ENSHBUP00000035448	Uncharacterized protein.	Si:ch211-263k4.2.	0.944
ENSHBUP00000027387	ENSHBUP00000009033	ENSHBUP00000027387	ENSHBUP00000009033	NR LBD domain-containing protein.	Nuclear receptor domain-containing protein.	0.866
ENSHBUP00000027387	LOC102306757	ENSHBUP00000027387	ENSHBUP00000020755	NR LBD domain-containing protein.	E1A binding protein p300 a.	0.407
ENSHBUP00000027387	ep300	ENSHBUP00000027387	ENSHBUP00000015535	NR LBD domain-containing protein.	E1A binding protein p300 b.	0.407
ENSHBUP00000027387	med1	ENSHBUP00000027387	ENSHBUP00000013910	NR LBD domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.570
FFAR2	ffar4	ENSHBUP00000027411	ENSHBUP00000034436	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.504
LOC102290675	ENSHBUP00000021923	ENSHBUP00000017367	ENSHBUP00000021923	Uncharacterized protein.	Uncharacterized protein.	0.576
LOC102290675	LOC102306757	ENSHBUP00000017367	ENSHBUP00000020755	Uncharacterized protein.	E1A binding protein p300 a.	0.513
LOC102290675	LOC102308982	ENSHBUP00000017367	ENSHBUP00000022261	Uncharacterized protein.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.822
LOC102290675	ZNF516	ENSHBUP00000017367	ENSHBUP00000008361	Uncharacterized protein.	Zinc finger protein 516.	0.576