8 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nf1	Neurofibromin 1b. (2772 aa)
	pnkd	PNKD metallo-beta-lactamase domain containing. (358 aa)
	rap1b	Uncharacterized protein. (184 aa)
	LOC102299497	RAP1A, member of RAS oncogene family a. (185 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (432 aa)
	LOC102309316	Uncharacterized protein. (185 aa)
	ENSHBUP00000028187	Si:ch73-71c20.5. (151 aa)
	fmr1	Fragile X mental retardation 1. (600 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102299497	LOC102309316	ENSHBUP00000010449	ENSHBUP00000026217	RAP1A, member of RAS oncogene family a.	Uncharacterized protein.	0.809
LOC102299497	nf1	ENSHBUP00000010449	ENSHBUP00000022675	RAP1A, member of RAS oncogene family a.	Neurofibromin 1b.	0.801
LOC102299497	prkn	ENSHBUP00000010449	ENSHBUP00000010501	RAP1A, member of RAS oncogene family a.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.574
LOC102299497	rap1b	ENSHBUP00000010449	ENSHBUP00000002548	RAP1A, member of RAS oncogene family a.	Uncharacterized protein.	0.809
LOC102309316	LOC102299497	ENSHBUP00000026217	ENSHBUP00000010449	Uncharacterized protein.	RAP1A, member of RAS oncogene family a.	0.809
LOC102309316	nf1	ENSHBUP00000026217	ENSHBUP00000022675	Uncharacterized protein.	Neurofibromin 1b.	0.801
LOC102309316	prkn	ENSHBUP00000026217	ENSHBUP00000010501	Uncharacterized protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.574
LOC102309316	rap1b	ENSHBUP00000026217	ENSHBUP00000002548	Uncharacterized protein.	Uncharacterized protein.	0.809
nf1	LOC102299497	ENSHBUP00000022675	ENSHBUP00000010449	Neurofibromin 1b.	RAP1A, member of RAS oncogene family a.	0.801
nf1	LOC102309316	ENSHBUP00000022675	ENSHBUP00000026217	Neurofibromin 1b.	Uncharacterized protein.	0.801
nf1	rap1b	ENSHBUP00000022675	ENSHBUP00000002548	Neurofibromin 1b.	Uncharacterized protein.	0.801
prkn	LOC102299497	ENSHBUP00000010501	ENSHBUP00000010449	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	RAP1A, member of RAS oncogene family a.	0.574
prkn	LOC102309316	ENSHBUP00000010501	ENSHBUP00000026217	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Uncharacterized protein.	0.574
prkn	rap1b	ENSHBUP00000010501	ENSHBUP00000002548	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Uncharacterized protein.	0.574
rap1b	LOC102299497	ENSHBUP00000002548	ENSHBUP00000010449	Uncharacterized protein.	RAP1A, member of RAS oncogene family a.	0.809
rap1b	LOC102309316	ENSHBUP00000002548	ENSHBUP00000026217	Uncharacterized protein.	Uncharacterized protein.	0.809
rap1b	nf1	ENSHBUP00000002548	ENSHBUP00000022675	Uncharacterized protein.	Neurofibromin 1b.	0.801
rap1b	prkn	ENSHBUP00000002548	ENSHBUP00000010501	Uncharacterized protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.574