(53 nodes) Synaptic vesicle endocytosis network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSHBUP00000016815	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (54 aa)
	LOC102297644	Intersectin 2b. (1585 aa)
	DNM1	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (821 aa)
	LOC102296820	Synaptotagmin Vb. (419 aa)
	ENSHBUP00000015771	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (54 aa)
	LOC102307010	ENTH domain-containing protein. (544 aa)
	ENSHBUP00000015763	Uncharacterized protein. (257 aa)
	LOC102288810	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (834 aa)
	LOC102289117	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (852 aa)
	ENSHBUP00000013557	ENTH domain-containing protein. (240 aa)
	ENSHBUP00000012412	Uncharacterized protein. (512 aa)
	ENSHBUP00000012387	EH domain-containing protein. (120 aa)
	LOC102309070	Si:ch211-200p22.4. (561 aa)
	LOC102300384	Synaptotagmin Ia. (422 aa)
	ENSHBUP00000008124	Stonin-1; May be involved in the endocytic machinery. (706 aa)
	LOC102296042	Gamma-synuclein; Belongs to the synuclein family. (111 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	LOC102288766	Synaptotagmin IIa. (428 aa)
	synj1	Synaptojanin 1. (1665 aa)
	ENSHBUP00000004691	COesterase domain-containing protein. (310 aa)
	nostrin	Nitric oxide synthase trafficking. (578 aa)
	sncb	Beta-synuclein; Belongs to the synuclein family. (117 aa)
	ENSHBUP00000003110	Uncharacterized protein. (755 aa)
	ENSHBUP00000003056	Uncharacterized protein. (917 aa)
	ENSHBUP00000002980	Si:ch211-233a24.2. (1920 aa)
	LOC102301331	ENTH domain-containing protein. (576 aa)
	nlgn1	Neuroligin 1. (601 aa)
	LOC102306383	Neuroligin 3b. (817 aa)
	LOC102293438	COesterase domain-containing protein. (872 aa)
	nlgn3	Neuroligin 3a. (836 aa)
	LOC102308269	Uncharacterized protein. (351 aa)
	LOC102301256	Uncharacterized protein; Belongs to the synuclein family. (127 aa)
	LOC102301058	Synaptotagmin Ib. (408 aa)
	fcho2	FCH domain only 2. (989 aa)
	LOC102313806	Synaptosome associated protein 91b. (646 aa)
	LOC102292847	Si:ch73-389b16.2. (1418 aa)
	ENSHBUP00000027907	ENTH domain-containing protein. (64 aa)
	LOC102297792	Neuroligin 4 X-linked a. (758 aa)
	LOC102292315	Uncharacterized protein. (430 aa)
	sncg	Gamma-synuclein; Belongs to the synuclein family. (124 aa)
	sh3gl2	SH3 domain containing GRB2 like 2a, endophilin A1. (363 aa)
	dennd1a	DENN/MADD domain containing 1A. (831 aa)
	ENSHBUP00000024728	COesterase domain-containing protein. (162 aa)
	LOC102291569	SH3-domain GRB2-like 1b. (363 aa)
	picalm	Phosphatidylinositol binding clathrin assembly protein b. (565 aa)
	dnm2	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa)
	LOC102311540	COesterase domain-containing protein. (229 aa)
	dnm1	Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (861 aa)
	LOC102293456	SH3-domain GRB2-like 3a. (324 aa)
	LOC102313675	Neuroligin 2b. (874 aa)
	ENSHBUP00000019300	Uncharacterized protein. (499 aa)
	sh3gl1	SH3-domain GRB2-like 1a. (369 aa)
	ENSHBUP00000018971	Intersectin 1 (SH3 domain protein). (1143 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNM1	ENSHBUP00000012387	ENSHBUP00000016615	ENSHBUP00000012387	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	EH domain-containing protein.	0.700
DNM1	ENSHBUP00000012412	ENSHBUP00000016615	ENSHBUP00000012412	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.827
DNM1	ENSHBUP00000018971	ENSHBUP00000016615	ENSHBUP00000018971	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Intersectin 1 (SH3 domain protein).	0.700
DNM1	ENSHBUP00000019300	ENSHBUP00000016615	ENSHBUP00000019300	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.700
DNM1	LOC102289117	ENSHBUP00000016615	ENSHBUP00000013630	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.509
DNM1	LOC102291569	ENSHBUP00000016615	ENSHBUP00000023696	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	SH3-domain GRB2-like 1b.	0.744
DNM1	LOC102293456	ENSHBUP00000016615	ENSHBUP00000020191	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	SH3-domain GRB2-like 3a.	0.744
DNM1	LOC102297644	ENSHBUP00000016615	ENSHBUP00000016814	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Intersectin 2b.	0.827
DNM1	LOC102308269	ENSHBUP00000016615	ENSHBUP00000033810	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.744
DNM1	dnm2	ENSHBUP00000016615	ENSHBUP00000023048	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.531
DNM1	sh3gl1	ENSHBUP00000016615	ENSHBUP00000019008	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	SH3-domain GRB2-like 1a.	0.702
DNM1	sh3gl2	ENSHBUP00000016615	ENSHBUP00000025041	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	SH3 domain containing GRB2 like 2a, endophilin A1.	0.744
DNM1	synj1	ENSHBUP00000016615	ENSHBUP00000006355	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Synaptojanin 1.	0.400
ENSHBUP00000002980	ENSHBUP00000003056	ENSHBUP00000002980	ENSHBUP00000003056	Si:ch211-233a24.2.	Uncharacterized protein.	0.900
ENSHBUP00000002980	ENSHBUP00000003110	ENSHBUP00000002980	ENSHBUP00000003110	Si:ch211-233a24.2.	Uncharacterized protein.	0.925
ENSHBUP00000003056	ENSHBUP00000002980	ENSHBUP00000003056	ENSHBUP00000002980	Uncharacterized protein.	Si:ch211-233a24.2.	0.900
ENSHBUP00000003056	ENSHBUP00000003110	ENSHBUP00000003056	ENSHBUP00000003110	Uncharacterized protein.	Uncharacterized protein.	0.920
ENSHBUP00000003110	ENSHBUP00000002980	ENSHBUP00000003110	ENSHBUP00000002980	Uncharacterized protein.	Si:ch211-233a24.2.	0.925
ENSHBUP00000003110	ENSHBUP00000003056	ENSHBUP00000003110	ENSHBUP00000003056	Uncharacterized protein.	Uncharacterized protein.	0.920
ENSHBUP00000012387	DNM1	ENSHBUP00000012387	ENSHBUP00000016615	EH domain-containing protein.	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.700