STRINGSTRING
LOC102314283 LOC102314283 LOC102304617 LOC102304617 LOC102289459 LOC102289459 grn grn nkx2-5 nkx2-5 llgl2 llgl2 LOC102299722 LOC102299722 LOC102291385 LOC102291385 il10 il10 htr2b htr2b pdgfb pdgfb vip vip LOC102296940 LOC102296940 LOC102308191 LOC102308191 atp5f1a atp5f1a f3 f3 ngfr ngfr GATA2 GATA2 LOC102309602 LOC102309602 wdr13 wdr13 LOC102296521 LOC102296521 xbp1 xbp1 ENSHBUP00000009061 ENSHBUP00000009061 eaf2 eaf2 sirt1 sirt1 ENSHBUP00000010293 ENSHBUP00000010293 map2k5 map2k5 fgf7 fgf7 ift74 ift74 LOC102314494 LOC102314494 vegfb vegfb LOC102309572 LOC102309572 LOC102292655 LOC102292655 LOC102304156 LOC102304156 LOC102300709 LOC102300709 LOC102298110 LOC102298110 LOC102290481 LOC102290481 cdkn1b cdkn1b vegfa vegfa LOC102290252 LOC102290252 LOC102289344 LOC102289344 APOH APOH deaf1 deaf1 ENSHBUP00000013761 ENSHBUP00000013761 med1 med1 aimp1 aimp1 LOC102292561 LOC102292561 LOC102302421 LOC102302421 LOC102296632 LOC102296632 bad bad LOC102299686 LOC102299686 scg2 scg2 sav1 sav1 tnmd tnmd dusp10 dusp10 LOC102307470 LOC102307470 ENSHBUP00000016109 ENSHBUP00000016109 VASH1 VASH1 pdx1 pdx1 st8sia1 st8sia1 sulf1 sulf1 ENSHBUP00000017560 ENSHBUP00000017560 ENSHBUP00000017574 ENSHBUP00000017574 phox2b phox2b LOC102289199 LOC102289199 LOC102288884 LOC102288884 ENSHBUP00000017602 ENSHBUP00000017602 LOC102306907 LOC102306907 sfrp2 sfrp2 LOC102291534 LOC102291534 fgf2 fgf2 pygo2 pygo2 AR AR sirt6 sirt6 fa2h fa2h bmpr2 bmpr2 stk11 stk11 LOC102304742 LOC102304742 LOC102296050 LOC102296050 rptor rptor LOC102305789 LOC102305789 ENSHBUP00000020099 ENSHBUP00000020099 aggf1 aggf1 LOC102310023 LOC102310023 vegfd vegfd LOC102310016 LOC102310016 ENSHBUP00000021250 ENSHBUP00000021250 nkx2-3 nkx2-3 brca2 brca2 lims1 lims1 ENSHBUP00000022635 ENSHBUP00000022635 nf1 nf1 rb1 rb1 rreb1 rreb1 il12b il12b LOC102304719 LOC102304719 cnmd cnmd ENSHBUP00000023652 ENSHBUP00000023652 mydgf mydgf LOC102301078 LOC102301078 ift52 ift52 stxbp4 stxbp4 bmp4 bmp4 dab2 dab2 LOC102295591 LOC102295591 smo smo LOC102289464 LOC102289464 ENSHBUP00000025985 ENSHBUP00000025985 LOC102296847 LOC102296847 wnt2b wnt2b LOC102307180 LOC102307180 mmrn2 mmrn2 tbc1d31 tbc1d31 LOC102311635 LOC102311635 prok2 prok2 hpn hpn LOC102288968 LOC102288968 id1 id1 LOC102293232 LOC102293232 flcn flcn tnfaip3 tnfaip3 WDR77 WDR77 cdc73 cdc73 LOC106633175 LOC106633175 rgcc rgcc LOC102298147 LOC102298147 APOH-2 APOH-2 LOC102293664 LOC102293664 errfi1 errfi1 LOC102288878 LOC102288878 agtr1 agtr1 LOC102306877 LOC102306877 hlx hlx sp1 sp1 ENSHBUP00000032881 ENSHBUP00000032881 pgf pgf ENSHBUP00000033201 ENSHBUP00000033201 tgfb2 tgfb2 ENSHBUP00000033838 ENSHBUP00000033838 LOC102295169 LOC102295169 LOC102297217 LOC102297217 LOC102290331 LOC102290331 LOC102292237 LOC102292237 ENSHBUP00000034659 ENSHBUP00000034659 aqp11 aqp11 ppard ppard pex2 pex2 igf2 igf2 ift80 ift80 ENSHBUP00000000637 ENSHBUP00000000637 LOC102296557 LOC102296557 CASK CASK LOC102290527 LOC102290527 vegfc vegfc vash2 vash2 LOC102297268 LOC102297268 ar ar
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102314283Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
LOC102304617Cyclin-dependent kinase inhibitor 1A. (169 aa)
LOC102289459ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (551 aa)
grnGranulin b. (828 aa)
nkx2-5NK2 homeobox 5. (320 aa)
llgl2LLGL scribble cell polarity complex component 2. (869 aa)
LOC102299722Uncharacterized protein. (435 aa)
LOC102291385Usher syndrome 1C binding protein 1. (683 aa)
il10Interleukin 10. (182 aa)
htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (478 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (549 aa)
vipVasoactive intestinal peptide. (150 aa)
LOC102296940Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
LOC102308191C2H2-type domain-containing protein. (598 aa)
atp5f1aATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (552 aa)
f3Coagulation factor IIIa. (286 aa)
ngfrNerve growth factor receptor a (TNFR superfamily, member 16). (357 aa)
GATA2GATA binding protein 2. (455 aa)
LOC102309602Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
wdr13WD repeat domain 13. (497 aa)
LOC102296521ADAM metallopeptidase domain 17b. (827 aa)
xbp1X-box binding protein 1. (260 aa)
ENSHBUP00000009061GRANULINS domain-containing protein. (138 aa)
eaf2ELL associated factor 2. (260 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (715 aa)
ENSHBUP00000010293Apelin receptor early endogenous ligand. (56 aa)
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (438 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
ift74Intraflagellar transport 74. (640 aa)
LOC102314494Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
vegfbPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (284 aa)
LOC102309572Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (165 aa)
LOC102292655Homeobox domain-containing protein. (194 aa)
LOC102304156Nuclear protein 1b. (74 aa)
LOC102300709Cyclin-dependent kinase inhibitor 1Cb. (208 aa)
LOC102298110ADAM metallopeptidase domain 17a. (861 aa)
LOC102290481Uncharacterized protein. (332 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (184 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
LOC102290252JunE proto-oncogene, AP-1 transcription factor subunit. (347 aa)
LOC102289344Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (131 aa)
APOHApolipoprotein H. (365 aa)
deaf1DEAF1 transcription factor. (627 aa)
ENSHBUP00000013761Secreted frizzled-related protein 2 like. (310 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1838 aa)
aimp1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1a. (317 aa)
LOC102292561G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (361 aa)
LOC102302421Nuclear receptor subfamily 1, group d, member 1. (597 aa)
LOC102296632Homeobox domain-containing protein. (359 aa)
badBCL2 associated agonist of cell death b. (158 aa)
LOC102299686Aminoacyl tRNA synthetase complex interacting multifunctional protein 1b. (329 aa)
scg2Uncharacterized protein. (627 aa)
sav1Salvador family WW domain containing protein 1. (414 aa)
tnmdTenomodulin. (299 aa)
dusp10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (480 aa)
LOC102307470Apolipoprotein Eb. (276 aa)
ENSHBUP00000016109Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (261 aa)
VASH1Vasohibin 1. (335 aa)
pdx1Pancreatic and duodenal homeobox 1. (256 aa)
st8sia1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (350 aa)
sulf1Sulfatase 1. (1163 aa)
ENSHBUP00000017560Uncharacterized protein. (101 aa)
ENSHBUP00000017574GRANULINS domain-containing protein. (54 aa)
phox2bPaired like homeobox 2Bb. (285 aa)
LOC102289199Uncharacterized protein. (206 aa)
LOC102288884Uncharacterized protein. (205 aa)
ENSHBUP00000017602Uncharacterized protein. (207 aa)
LOC102306907Secretogranin II (chromogranin C), b. (622 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
LOC102291534TERF1 (TRF1)-interacting nuclear factor 2. (579 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
pygo2Pygopus homolog 2 (Drosophila). (587 aa)
ARAndrogen receptor. (763 aa)
sirt6Sirtuin 6. (351 aa)
fa2hFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (381 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1067 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (436 aa)
LOC102304742Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
LOC102296050Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1199 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1358 aa)
LOC102305789Transforming growth factor, alpha. (254 aa)
ENSHBUP00000020099Prokineticin 1. (102 aa)
aggf1Angiogenic factor with G patch and FHA domains 1. (742 aa)
LOC102310023Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (515 aa)
vegfdVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (311 aa)
LOC102310016Nuclear receptor subfamily 1, group D, member 4b. (587 aa)
ENSHBUP00000021250RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (156 aa)
nkx2-3NK2 homeobox 3. (344 aa)
brca2BRCA2 DNA repair associated. (3303 aa)
lims1LIM domain-containing protein. (405 aa)
ENSHBUP00000022635Cyclin-dependent kinase inhibitor 1A. (163 aa)
nf1Neurofibromin 1b. (2772 aa)
rb1Retinoblastoma 1. (912 aa)
rreb1Ras responsive element binding protein 1a. (1881 aa)
il12bInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (347 aa)
LOC102304719Uncharacterized protein. (181 aa)
cnmdChondromodulin. (307 aa)
ENSHBUP00000023652Interfer-bind domain-containing protein. (180 aa)
mydgfMyeloid-derived growth factor. (210 aa)
LOC102301078Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa)
ift52Intraflagellar transport 52 homolog (Chlamydomonas). (434 aa)
stxbp4Syntaxin binding protein 4. (720 aa)
bmp4Bone morphogenetic protein 4. (403 aa)
dab2DAB adaptor protein 2. (779 aa)
LOC102295591Growth arrest-specific 1b. (259 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (825 aa)
LOC102289464Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (935 aa)
ENSHBUP00000025985Epithelial cell adhesion molecule. (149 aa)
LOC102296847Uncharacterized protein. (1408 aa)
wnt2bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa)
LOC102307180Uncharacterized protein. (157 aa)
mmrn2Multimerin 2a. (1092 aa)
tbc1d31TBC1 domain family, member 31. (1050 aa)
LOC102311635GATA binding protein 2a. (465 aa)
prok2Prokineticin 2. (135 aa)
hpnHepsin; Belongs to the peptidase S1 family. (427 aa)
LOC102288968Epithelial mitogen homolog (mouse). (164 aa)
id1Inhibitor of DNA binding 1, HLH protein. (131 aa)
LOC102293232Extracellular sulfatase. (884 aa)
flcnFolliculin. (556 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (818 aa)
WDR77WD repeat domain 77. (337 aa)
cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (512 aa)
LOC106633175LRRCT domain-containing protein. (334 aa)
rgccRegulator of cell cycle. (128 aa)
LOC102298147Uncharacterized protein. (836 aa)
APOH-2Apolipoprotein H. (350 aa)
LOC102293664Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (501 aa)
errfi1ERBB receptor feedback inhibitor 1a. (406 aa)
LOC102288878Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (361 aa)
agtr1Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. (363 aa)
LOC102306877Apolipoprotein Ea. (262 aa)
hlxH2.0-like homeo box 1 (Drosophila). (379 aa)
sp1Sp1 transcription factor. (707 aa)
ENSHBUP00000032881Fibroblast growth factor binding protein 1b. (219 aa)
pgfPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (161 aa)
ENSHBUP00000033201Uncharacterized protein. (74 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
ENSHBUP00000033838Apelin receptor b; Belongs to the G-protein coupled receptor 1 family. (354 aa)
LOC102295169Uncharacterized protein. (237 aa)
LOC102297217Si:dkey-175m17.7. (891 aa)
LOC102290331Baculoviral IAP repeat containing 5a. (142 aa)
LOC102292237Chondromodulin. (283 aa)
ENSHBUP00000034659Prokineticin 1. (100 aa)
aqp11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
ppardPeroxisome proliferator-activated receptor delta b. (509 aa)
pex2Peroxisomal biogenesis factor 2. (351 aa)
igf2Insulin-like growth factor 2b. (215 aa)
ift80Intraflagellar transport 80 homolog (Chlamydomonas). (779 aa)
ENSHBUP00000000637LIM zinc-binding domain-containing protein. (88 aa)
LOC102296557Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (956 aa)
LOC102290527Bone morphogenetic protein 16. (531 aa)
vegfcVascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (394 aa)
vash2Vasohibin 2. (370 aa)
LOC102297268Uncharacterized protein. (204 aa)
arAndrogen receptor. (692 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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