(29 nodes) Cardiac muscle cell development network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	asb2	Ankyrin repeat and SOCS box containing 2b. (580 aa)
	LOC102295647	Titin-cap (telethonin). (179 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
	adprhl1	ADP-ribosylhydrolase like 1. (358 aa)
	nkx2-5	NK2 homeobox 5. (320 aa)
	maml1	Mastermind-like transcriptional coactivator 1. (972 aa)
	nrap	Nebulin-related anchoring protein. (1686 aa)
	ENSHBUP00000005352	Uncharacterized protein. (271 aa)
	csrp3	Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa)
	ENSHBUP00000010338	Uncharacterized protein. (1404 aa)
	ENSHBUP00000010906	Uncharacterized protein. (133 aa)
	sgcb	Sarcoglycan, beta (dystrophin-associated glycoprotein). (310 aa)
	LOC102300920	Uncharacterized protein. (1796 aa)
	LOC102313643	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (428 aa)
	LOC102296085	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (684 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	opa1	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1047 aa)
	ENSHBUP00000024997	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (292 aa)
	LOC102293267	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (362 aa)
	SRF	Serum response factor. (597 aa)
	LOC102299365	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (488 aa)
	ENSHBUP00000028611	Uncharacterized protein. (389 aa)
	bves	Blood vessel epicardial substance. (348 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	LOC102295114	MADS-box domain-containing protein. (503 aa)
	bmp2	Bone morphogenetic protein 2b. (418 aa)
	ENSHBUP00000031755	Alpha-type protein kinase domain-containing protein. (184 aa)
	ENSHBUP00000032518	Uncharacterized protein. (320 aa)
	LOC102297417	Uncharacterized protein. (1656 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000010338	ENSHBUP00000028611	ENSHBUP00000010338	ENSHBUP00000028611	Uncharacterized protein.	Uncharacterized protein.	0.822
ENSHBUP00000010338	LOC102295647	ENSHBUP00000010338	ENSHBUP00000000530	Uncharacterized protein.	Titin-cap (telethonin).	0.536
ENSHBUP00000010906	LOC102295647	ENSHBUP00000010906	ENSHBUP00000000530	Uncharacterized protein.	Titin-cap (telethonin).	0.515
ENSHBUP00000024997	LOC102313643	ENSHBUP00000024997	ENSHBUP00000015836	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.658
ENSHBUP00000028611	ENSHBUP00000010338	ENSHBUP00000028611	ENSHBUP00000010338	Uncharacterized protein.	Uncharacterized protein.	0.822
ENSHBUP00000028611	LOC102295647	ENSHBUP00000028611	ENSHBUP00000000530	Uncharacterized protein.	Titin-cap (telethonin).	0.536
LOC102293267	LOC102313643	ENSHBUP00000025068	ENSHBUP00000015836	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.658
LOC102295114	SRF	ENSHBUP00000030051	ENSHBUP00000027140	MADS-box domain-containing protein.	Serum response factor.	0.854
LOC102295114	nkx2-5	ENSHBUP00000030051	ENSHBUP00000002929	MADS-box domain-containing protein.	NK2 homeobox 5.	0.524
LOC102295647	ENSHBUP00000010338	ENSHBUP00000000530	ENSHBUP00000010338	Titin-cap (telethonin).	Uncharacterized protein.	0.536
LOC102295647	ENSHBUP00000010906	ENSHBUP00000000530	ENSHBUP00000010906	Titin-cap (telethonin).	Uncharacterized protein.	0.515
LOC102295647	ENSHBUP00000028611	ENSHBUP00000000530	ENSHBUP00000028611	Titin-cap (telethonin).	Uncharacterized protein.	0.536
LOC102295647	csrp3	ENSHBUP00000000530	ENSHBUP00000006604	Titin-cap (telethonin).	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	0.697
LOC102295647	nrap	ENSHBUP00000000530	ENSHBUP00000003321	Titin-cap (telethonin).	Nebulin-related anchoring protein.	0.556
LOC102313643	ENSHBUP00000024997	ENSHBUP00000015836	ENSHBUP00000024997	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	0.658
LOC102313643	LOC102293267	ENSHBUP00000015836	ENSHBUP00000025068	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.658
SRF	LOC102295114	ENSHBUP00000027140	ENSHBUP00000030051	Serum response factor.	MADS-box domain-containing protein.	0.854
SRF	nkx2-5	ENSHBUP00000027140	ENSHBUP00000002929	Serum response factor.	NK2 homeobox 5.	0.524
atg5	mtor	ENSHBUP00000030001	ENSHBUP00000032917	Autophagy protein 5; Involved in autophagic vesicle formation.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.623
atg5	opa1	ENSHBUP00000030001	ENSHBUP00000024387	Autophagy protein 5; Involved in autophagic vesicle formation.	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.581