(17 nodes) Dendritic spine development network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102311613	Cell division cycle 42. (191 aa)
	srgap2	SLIT-ROBO Rho GTPase activating protein 2. (1124 aa)
	LOC102309694	Uncharacterized protein. (1720 aa)
	PAK3	Non-specific serine/threonine protein kinase. (575 aa)
	dock10	Dedicator of cytokinesis 10; Belongs to the DOCK family. (2031 aa)
	ENSHBUP00000012616	Uncharacterized protein. (120 aa)
	shank3	SH3 and multiple ankyrin repeat domains 3a. (1971 aa)
	ENSHBUP00000008174	SAM domain-containing protein. (1681 aa)
	CDC42	Cell division cycle 42. (191 aa)
	ENSHBUP00000003545	Uncharacterized protein. (1121 aa)
	pak1	Non-specific serine/threonine protein kinase. (583 aa)
	LOC102306146	Eph receptor B3a. (926 aa)
	ENSHBUP00000031317	P21 protein (Cdc42/Rac)-activated kinase 2b. (157 aa)
	LOC102294556	Non-specific serine/threonine protein kinase. (513 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (838 aa)
	ENSHBUP00000025117	Uncharacterized protein. (118 aa)
	ephb3	Uncharacterized protein. (985 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSHBUP00000003545	ENSHBUP00000007818	ENSHBUP00000003545	Cell division cycle 42.	Uncharacterized protein.	0.766
CDC42	ENSHBUP00000008174	ENSHBUP00000007818	ENSHBUP00000008174	Cell division cycle 42.	SAM domain-containing protein.	0.766
CDC42	ENSHBUP00000012616	ENSHBUP00000007818	ENSHBUP00000012616	Cell division cycle 42.	Uncharacterized protein.	0.766
CDC42	ENSHBUP00000031317	ENSHBUP00000007818	ENSHBUP00000031317	Cell division cycle 42.	P21 protein (Cdc42/Rac)-activated kinase 2b.	0.951
CDC42	LOC102294556	ENSHBUP00000007818	ENSHBUP00000029573	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.951
CDC42	LOC102306146	ENSHBUP00000007818	ENSHBUP00000031818	Cell division cycle 42.	Eph receptor B3a.	0.482
CDC42	LOC102309694	ENSHBUP00000007818	ENSHBUP00000023000	Cell division cycle 42.	Uncharacterized protein.	0.766
CDC42	PAK3	ENSHBUP00000007818	ENSHBUP00000020156	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.971
CDC42	dock10	ENSHBUP00000007818	ENSHBUP00000016250	Cell division cycle 42.	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.954
CDC42	ephb3	ENSHBUP00000007818	ENSHBUP00000024894	Cell division cycle 42.	Uncharacterized protein.	0.482
CDC42	pak1	ENSHBUP00000007818	ENSHBUP00000034780	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.971
CDC42	shank1	ENSHBUP00000007818	ENSHBUP00000026761	Cell division cycle 42.	SH3 and multiple ankyrin repeat domains 1.	0.766
CDC42	shank3	ENSHBUP00000007818	ENSHBUP00000009291	Cell division cycle 42.	SH3 and multiple ankyrin repeat domains 3a.	0.766
CDC42	srgap2	ENSHBUP00000007818	ENSHBUP00000024599	Cell division cycle 42.	SLIT-ROBO Rho GTPase activating protein 2.	0.673
ENSHBUP00000003545	CDC42	ENSHBUP00000003545	ENSHBUP00000007818	Uncharacterized protein.	Cell division cycle 42.	0.766
ENSHBUP00000003545	ENSHBUP00000008174	ENSHBUP00000003545	ENSHBUP00000008174	Uncharacterized protein.	SAM domain-containing protein.	0.646
ENSHBUP00000003545	ENSHBUP00000012616	ENSHBUP00000003545	ENSHBUP00000012616	Uncharacterized protein.	Uncharacterized protein.	0.629
ENSHBUP00000003545	LOC102309694	ENSHBUP00000003545	ENSHBUP00000023000	Uncharacterized protein.	Uncharacterized protein.	0.629
ENSHBUP00000003545	LOC102311613	ENSHBUP00000003545	ENSHBUP00000024611	Uncharacterized protein.	Cell division cycle 42.	0.766
ENSHBUP00000003545	shank1	ENSHBUP00000003545	ENSHBUP00000026761	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 1.	0.691