(38 nodes) Negative regulation of small molecule metabolic process network (Haplochromis burtoni)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	pibf1	Progesterone immunomodulatory binding factor 1. (675 aa)
	slc27a4	Solute carrier family 27 member 4. (643 aa)
	LOC102300963	Uncharacterized protein. (416 aa)
	ENSHBUP00000002129	Uncharacterized protein. (194 aa)
	brca1	Uncharacterized protein. (1388 aa)
	LOC102302155	ATCAY kinesin light chain interacting caytaxin a. (373 aa)
	LOC102294536	TP53 induced glycolysis regulatory phosphatase b. (298 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	sirt4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (311 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (715 aa)
	LOC102300740	TP53 induced glycolysis regulatory phosphatase a. (271 aa)
	LOC102294392	ATCAY kinesin light chain interacting caytaxin b. (352 aa)
	fgf19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	LOC102304156	Nuclear protein 1b. (74 aa)
	LOC102305701	Dickkopf WNT signaling pathway inhibitor 3a. (275 aa)
	pid1	Phosphotyrosine interaction domain containing 1. (225 aa)
	ep300	E1A binding protein p300 b. (2764 aa)
	acmsd	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
	LOC102307470	Apolipoprotein Eb. (276 aa)
	soga1	Suppressor of glucose, autophagy associated 1. (1918 aa)
	plek	Pleckstrin. (351 aa)
	sirt6	Sirtuin 6. (351 aa)
	ENSHBUP00000019977	Nuclear protein 1a. (76 aa)
	LOC102306757	E1A binding protein p300 a. (2600 aa)
	lepr	Leptin receptor. (1194 aa)
	LOC102292472	Dickkopf WNT signaling pathway inhibitor 3b. (270 aa)
	ENSHBUP00000025117	Uncharacterized protein. (118 aa)
	snai2	Snail family zinc finger 2. (260 aa)
	tspo	Translocator protein. (167 aa)
	flcn	Folliculin. (556 aa)
	LOC102311744	Tribbles pseudokinase 3. (353 aa)
	LOC102306877	Apolipoprotein Ea. (262 aa)
	LOC102298106	PDZ domain containing 3b. (505 aa)
	rd3	Retinal degeneration 3, GUCY2D regulator. (218 aa)
	etfbkmt	Electron transfer flavoprotein subunit beta lysine methyltransferase. (258 aa)
	fam3c	Family with sequence similarity 3 member C. (227 aa)
	LOC102312414	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (135 aa)
	wdtc1	WD and tetratricopeptide repeats 1. (675 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000025117	LOC102306757	ENSHBUP00000025117	ENSHBUP00000020755	Uncharacterized protein.	E1A binding protein p300 a.	0.658
ENSHBUP00000025117	ep300	ENSHBUP00000025117	ENSHBUP00000015535	Uncharacterized protein.	E1A binding protein p300 b.	0.658
LOC102294392	LOC102306757	ENSHBUP00000011625	ENSHBUP00000020755	ATCAY kinesin light chain interacting caytaxin b.	E1A binding protein p300 a.	0.628
LOC102294392	LOC102312414	ENSHBUP00000011625	ENSHBUP00000033101	ATCAY kinesin light chain interacting caytaxin b.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.745
LOC102294392	ep300	ENSHBUP00000011625	ENSHBUP00000015535	ATCAY kinesin light chain interacting caytaxin b.	E1A binding protein p300 b.	0.628
LOC102294536	LOC102300740	ENSHBUP00000008923	ENSHBUP00000011273	TP53 induced glycolysis regulatory phosphatase b.	TP53 induced glycolysis regulatory phosphatase a.	0.853
LOC102300740	LOC102294536	ENSHBUP00000011273	ENSHBUP00000008923	TP53 induced glycolysis regulatory phosphatase a.	TP53 induced glycolysis regulatory phosphatase b.	0.853
LOC102304156	LOC102306757	ENSHBUP00000011967	ENSHBUP00000020755	Nuclear protein 1b.	E1A binding protein p300 a.	0.411
LOC102304156	ep300	ENSHBUP00000011967	ENSHBUP00000015535	Nuclear protein 1b.	E1A binding protein p300 b.	0.411
LOC102306757	ENSHBUP00000025117	ENSHBUP00000020755	ENSHBUP00000025117	E1A binding protein p300 a.	Uncharacterized protein.	0.658
LOC102306757	LOC102294392	ENSHBUP00000020755	ENSHBUP00000011625	E1A binding protein p300 a.	ATCAY kinesin light chain interacting caytaxin b.	0.628
LOC102306757	LOC102304156	ENSHBUP00000020755	ENSHBUP00000011967	E1A binding protein p300 a.	Nuclear protein 1b.	0.411
LOC102306757	brca1	ENSHBUP00000020755	ENSHBUP00000003104	E1A binding protein p300 a.	Uncharacterized protein.	0.798
LOC102306757	parp1	ENSHBUP00000020755	ENSHBUP00000008939	E1A binding protein p300 a.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.661
LOC102306757	sirt1	ENSHBUP00000020755	ENSHBUP00000009767	E1A binding protein p300 a.	Deacetylase sirtuin-type domain-containing protein.	0.718
LOC102306757	sirt6	ENSHBUP00000020755	ENSHBUP00000019117	E1A binding protein p300 a.	Sirtuin 6.	0.454
LOC102306757	snai2	ENSHBUP00000020755	ENSHBUP00000025652	E1A binding protein p300 a.	Snail family zinc finger 2.	0.566
LOC102312414	LOC102294392	ENSHBUP00000033101	ENSHBUP00000011625	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	ATCAY kinesin light chain interacting caytaxin b.	0.745
brca1	LOC102306757	ENSHBUP00000003104	ENSHBUP00000020755	Uncharacterized protein.	E1A binding protein p300 a.	0.798
brca1	ep300	ENSHBUP00000003104	ENSHBUP00000015535	Uncharacterized protein.	E1A binding protein p300 b.	0.798