Genes that are sometimes fused into single open reading frames.
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Experiments
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSHBUP00000013815
GTP cyclohydrolase 1. (173 aa)
dhfr
Dihydrofolate reductase. (161 aa)
LOC102304432
GTP cyclohydrolase 2. (221 aa)
nfe2l2
Nuclear factor, erythroid 2-like 2a. (598 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153 Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni