13 items (Haplochromis burtoni) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	gps1	G protein pathway suppressor 1. (487 aa)
	cops5	COP9 signalosome subunit 5. (334 aa)
	cops8	COP9 signalosome subunit 8. (191 aa)
	themis2	Thymocyte selection associated family member 2. (698 aa)
	LOC102293492	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (449 aa)
	cops7a	COP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
	cops4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (321 aa)
	cops2	COP9 signalosome subunit 2. (443 aa)
	adss1	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
	cops3	COP9 signalosome subunit 3. (423 aa)
	LOC102294187	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (473 aa)
	COPS6	COP9 signalosome subunit 6. (346 aa)
	tespa1	KRAP_IP3R_bind domain-containing protein. (671 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPS6	cops2	ENSHBUP00000025144	ENSHBUP00000028598	COP9 signalosome subunit 6.	COP9 signalosome subunit 2.	0.999
COPS6	cops3	ENSHBUP00000025144	ENSHBUP00000031395	COP9 signalosome subunit 6.	COP9 signalosome subunit 3.	0.999
COPS6	cops4	ENSHBUP00000025144	ENSHBUP00000028387	COP9 signalosome subunit 6.	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).	0.999
COPS6	cops5	ENSHBUP00000025144	ENSHBUP00000017010	COP9 signalosome subunit 6.	COP9 signalosome subunit 5.	0.998
COPS6	cops7a	ENSHBUP00000025144	ENSHBUP00000014816	COP9 signalosome subunit 6.	COP9 constitutive photomorphogenic homolog subunit 7A.	0.995
COPS6	cops8	ENSHBUP00000025144	ENSHBUP00000000049	COP9 signalosome subunit 6.	COP9 signalosome subunit 8.	0.997
COPS6	gps1	ENSHBUP00000025144	ENSHBUP00000017219	COP9 signalosome subunit 6.	G protein pathway suppressor 1.	0.999
LOC102293492	LOC102294187	ENSHBUP00000011998	ENSHBUP00000019674	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.851
LOC102293492	adss1	ENSHBUP00000011998	ENSHBUP00000030900	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.851
LOC102294187	LOC102293492	ENSHBUP00000019674	ENSHBUP00000011998	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.851
LOC102294187	adss1	ENSHBUP00000019674	ENSHBUP00000030900	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.852
adss1	LOC102293492	ENSHBUP00000030900	ENSHBUP00000011998	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.851
adss1	LOC102294187	ENSHBUP00000030900	ENSHBUP00000019674	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.852
cops2	COPS6	ENSHBUP00000028598	ENSHBUP00000025144	COP9 signalosome subunit 2.	COP9 signalosome subunit 6.	0.999
cops2	cops3	ENSHBUP00000028598	ENSHBUP00000031395	COP9 signalosome subunit 2.	COP9 signalosome subunit 3.	0.999
cops2	cops4	ENSHBUP00000028598	ENSHBUP00000028387	COP9 signalosome subunit 2.	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).	0.999
cops2	cops5	ENSHBUP00000028598	ENSHBUP00000017010	COP9 signalosome subunit 2.	COP9 signalosome subunit 5.	0.999
cops2	cops7a	ENSHBUP00000028598	ENSHBUP00000014816	COP9 signalosome subunit 2.	COP9 constitutive photomorphogenic homolog subunit 7A.	0.994
cops2	cops8	ENSHBUP00000028598	ENSHBUP00000000049	COP9 signalosome subunit 2.	COP9 signalosome subunit 8.	0.999
cops2	gps1	ENSHBUP00000028598	ENSHBUP00000017219	COP9 signalosome subunit 2.	G protein pathway suppressor 1.	0.999