STRINGSTRING
LOC102298446 LOC102298446 ten1 ten1 ENSHBUP00000023677 ENSHBUP00000023677 ska1 ska1 CBX1 CBX1 nbn nbn LOC102293738 LOC102293738 cenpt cenpt ENSHBUP00000025428 ENSHBUP00000025428 cenpl cenpl ndc80 ndc80 LOC102311631 LOC102311631 nsmce4a nsmce4a ENSHBUP00000027738 ENSHBUP00000027738 mtbp mtbp lrwd1 lrwd1 cenph cenph LOC102312082 LOC102312082 LOC102309855 LOC102309855 ttk ttk cenpw cenpw dhx36 dhx36 LOC102291559 LOC102291559 cbx3 cbx3 nek2 nek2 cdt1 cdt1 dna2 dna2 CBX1-2 CBX1-2 tert tert incenp incenp recql4 recql4 zw10 zw10 ENSHBUP00000032873 ENSHBUP00000032873 terf1 terf1 LOC102311321 LOC102311321 terf2 terf2 smarca4 smarca4 LOC102303237 LOC102303237 rsph10b rsph10b cenpv cenpv LOC102290331 LOC102290331 dclre1b dclre1b gpatch11 gpatch11 LOC102303125 LOC102303125 nsmce1 nsmce1 fbxo28 fbxo28 mis12 mis12 rnf8 rnf8 anapc16 anapc16 cenpf cenpf cenpk cenpk rcc2 rcc2 seh1l seh1l LOC102291534 LOC102291534 ENSHBUP00000018527 ENSHBUP00000018527 ENSHBUP00000018665 ENSHBUP00000018665 spc24 spc24 sirt6 sirt6 ENSHBUP00000019136 ENSHBUP00000019136 ENSHBUP00000019957 ENSHBUP00000019957 smc5 smc5 mki67 mki67 nuf2 nuf2 stn1 stn1 atrx atrx bub1 bub1 kmt5b kmt5b sgo1 sgo1 ska3 ska3 LOC102295711 LOC102295711 ENSHBUP00000002926 ENSHBUP00000002926 nsl1 nsl1 bod1 bod1 WDSUB1 WDSUB1 LOC102303826 LOC102303826 spdl1 spdl1 fam43a fam43a cbx5 cbx5 spc25 spc25 LOC102291816 LOC102291816 smarca2 smarca2 bod1l1 bod1l1 fam43b fam43b ENSHBUP00000005316 ENSHBUP00000005316 zbtb48 zbtb48 rif1 rif1 kntc1 kntc1 kdm1a kdm1a znf827 znf827 ckap5 ckap5 LOC102304128 LOC102304128 terf2ip terf2ip hells hells knl1 knl1 zwilch zwilch LOC102290918 LOC102290918 LOC102290509 LOC102290509 terb2 terb2 LOC102304520 LOC102304520 cenpi cenpi bub1b bub1b cenpn cenpn ska2 ska2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102298446Uncharacterized protein. (273 aa)
ten1TEN1 subunit of CST complex. (130 aa)
ENSHBUP00000023677Protection of telomeres 1 homolog. (528 aa)
ska1Spindle and kinetochore associated complex subunit 1. (245 aa)
CBX1Chromobox homolog 1b (HP1 beta homolog Drosophila). (200 aa)
nbnNibrin. (779 aa)
LOC102293738Uncharacterized protein. (1028 aa)
cenptCENP-T_C domain-containing protein. (899 aa)
ENSHBUP00000025428Peptidase C31 domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (536 aa)
cenplCentromere protein L. (356 aa)
ndc80NDC80 kinetochore complex component. (639 aa)
LOC102311631Si:dkey-6i22.5. (226 aa)
nsmce4aNon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (349 aa)
ENSHBUP00000027738Uncharacterized protein. (482 aa)
mtbpMDM2 binding protein. (869 aa)
lrwd1Leucine-rich repeats and WD repeat domain containing 1. (743 aa)
cenphCENP-H domain-containing protein. (268 aa)
LOC102312082Cysteine three histidine 1. (295 aa)
LOC102309855N-acetyltransferase domain-containing protein. (256 aa)
ttkTtk protein kinase. (1006 aa)
cenpwUncharacterized protein. (75 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1063 aa)
LOC102291559Uncharacterized protein. (1288 aa)
cbx3Chromobox homolog 3b. (231 aa)
nek2NIMA-related kinase 2. (413 aa)
cdt1Chromatin licensing and DNA replication factor 1. (607 aa)
dna2DNA replication helicase/nuclease 2. (1401 aa)
CBX1-2Uncharacterized protein. (213 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1084 aa)
incenpUncharacterized protein. (837 aa)
recql4RecQ helicase-like 4. (1577 aa)
zw10Zw10 kinetochore protein. (766 aa)
ENSHBUP00000032873WD_REPEATS_REGION domain-containing protein. (163 aa)
terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (366 aa)
LOC102311321HTH myb-type domain-containing protein. (740 aa)
terf2HTH myb-type domain-containing protein. (561 aa)
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1660 aa)
LOC102303237AIG1-type G domain-containing protein. (555 aa)
rsph10bRadial spoke head 10 homolog B. (702 aa)
cenpvCentromere protein V. (128 aa)
LOC102290331Baculoviral IAP repeat containing 5a. (142 aa)
dclre1bDNA cross-link repair 1B. (586 aa)
gpatch11G patch domain containing 11. (194 aa)
LOC102303125Uncharacterized protein. (379 aa)
nsmce1NSE1 homolog, SMC5-SMC6 complex component. (264 aa)
fbxo28F-box protein 28. (378 aa)
mis12MIS12 kinetochore complex component. (231 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (464 aa)
anapc16Anaphase promoting complex subunit 16. (108 aa)
cenpfCentromere protein F. (2259 aa)
cenpkCentromere protein K. (262 aa)
rcc2Regulator of chromosome condensation 2. (494 aa)
seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (351 aa)
LOC102291534TERF1 (TRF1)-interacting nuclear factor 2. (579 aa)
ENSHBUP00000018527EGF-like domain-containing protein. (102 aa)
ENSHBUP00000018665Uncharacterized protein. (196 aa)
spc24SPC24 component of NDC80 kinetochore complex. (199 aa)
sirt6Sirtuin 6. (351 aa)
ENSHBUP00000019136AIG1-type G domain-containing protein. (520 aa)
ENSHBUP00000019957Zinc finger protein 618. (798 aa)
smc5SMC_N domain-containing protein. (1078 aa)
mki67Marker of proliferation Ki-67. (1892 aa)
nuf2UF2 component of NDC80 kinetochore complex. (436 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (365 aa)
atrxATRX chromatin remodeler. (1871 aa)
bub1BUB1 mitotic checkpoint serine/threonine kinase. (1199 aa)
kmt5bLysine methyltransferase 5B. (910 aa)
sgo1Shugoshin_C domain-containing protein. (718 aa)
ska3Spindle and kinetochore associated complex subunit 3. (603 aa)
LOC102295711Baculoviral IAP repeat containing 5b. (144 aa)
ENSHBUP00000002926ATRX chromatin remodeler, like. (1369 aa)
nsl1NSL1 component of MIS12 kinetochore complex. (258 aa)
bod1Uncharacterized protein. (426 aa)
WDSUB1WD repeat, sterile alpha motif and U-box domain containing 1. (487 aa)
LOC102303826Uncharacterized protein. (1657 aa)
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (574 aa)
fam43aFamily with sequence similarity 43 member A. (356 aa)
cbx5Chromobox homolog 5 (HP1 alpha homolog, Drosophila). (199 aa)
spc25SPC25 component of NDC80 kinetochore complex. (236 aa)
LOC102291816Si:ch211-220i18.4; Belongs to the protein kinase superfamily. (432 aa)
smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1588 aa)
bod1l1Uncharacterized protein. (1272 aa)
fam43bFamily with sequence similarity 43 member B. (305 aa)
ENSHBUP00000005316Uncharacterized protein. (172 aa)
zbtb48Zinc finger and BTB domain containing 48. (712 aa)
rif1Replication timing regulatory factor 1. (2354 aa)
kntc1Kinetochore associated 1. (2083 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (827 aa)
znf827Zinc finger protein 827. (1527 aa)
ckap5Cytoskeleton associated protein 5. (1599 aa)
LOC102304128SET domain-containing protein. (2044 aa)
terf2ipUncharacterized protein. (685 aa)
hellsHelicase, lymphoid specific. (854 aa)
knl1Knl1_RWD_C domain-containing protein. (1829 aa)
zwilchZwilch kinetochore protein. (609 aa)
LOC102290918Uncharacterized protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1034 aa)
LOC102290509Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (560 aa)
terb2Telomere repeat binding bouquet formation protein 2. (203 aa)
LOC102304520Protein kinase domain-containing protein. (612 aa)
cenpiCentromere protein I. (733 aa)
bub1bBUB1 mitotic checkpoint serine/threonine kinase Bb. (426 aa)
cenpnCentromere protein N. (348 aa)
ska2Spindle and kinetochore associated complex subunit 2. (224 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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