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hmgcl hmgcl LOC102290305 LOC102290305 dpyd dpyd LOC102293685 LOC102293685 umps umps gla gla dera dera hoga1 hoga1 SPAM1-3 SPAM1-3 LOC102304656 LOC102304656 mocs1 mocs1 LOC102307292 LOC102307292 LOC102298294 LOC102298294 alad alad dus1l dus1l taldo1 taldo1 LOC102293158 LOC102293158 LOC102299107 LOC102299107 hao1 hao1 npl npl rsad1 rsad1 LOC102301770 LOC102301770 SPAM1-2 SPAM1-2 LOC102308618 LOC102308618 SPAM1 SPAM1 impdh2 impdh2 lias lias HYAL2 HYAL2 LOC102304771 LOC102304771 gmpr gmpr QPRT QPRT LOC102291647 LOC102291647 LOC102312558 LOC102312558 LOC102294184 LOC102294184 LOC102290730 LOC102290730 pc pc LOC102299807 LOC102299807 LOC102304959 LOC102304959 aldoc aldoc dus4l dus4l ENSHBUP00000030000 ENSHBUP00000030000 naga naga LOC102306995 LOC102306995 HYAL2-2 HYAL2-2 LOC102312042 LOC102312042 hmgcll1 hmgcll1 LOC102308314 LOC102308314 hao2 hao2 rsad2 rsad2 LOC102292801 LOC102292801 dhodh dhodh LOC102305459 LOC102305459 dus3l dus3l nampt nampt dus2 dus2 naprt naprt
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hmgcl3-hydroxy-3-methylglutaryl-CoA lyase. (337 aa)
LOC102290305Triosephosphate isomerase. (248 aa)
dpydDihydropyrimidine dehydrogenase b. (987 aa)
LOC102293685Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (611 aa)
umpsUridine monophosphate synthetase. (497 aa)
glaAlpha-galactosidase. (430 aa)
deraDeoxyribose-phosphate aldolase (putative). (318 aa)
hoga14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (312 aa)
SPAM1-3Hyaluronidase. (746 aa)
LOC102304656Triosephosphate isomerase. (254 aa)
mocs1Molybdenum cofactor synthesis 1. (404 aa)
LOC102307292AFP-like domain-containing protein. (282 aa)
LOC102298294GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (348 aa)
aladDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (331 aa)
dus1lDihydrouridine synthase 1-like (S. cerevisiae). (485 aa)
taldo1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (338 aa)
LOC102293158Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
LOC102299107Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
hao1Hydroxyacid oxidase (glycolate oxidase) 1. (356 aa)
nplN-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); Belongs to the DapA family. (309 aa)
rsad1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (442 aa)
LOC102301770Hyaluronidase. (441 aa)
SPAM1-2Hyaluronidase. (444 aa)
LOC102308618Hyaluronidase. (515 aa)
SPAM1Hyaluronidase. (435 aa)
impdh2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (538 aa)
liasLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (385 aa)
HYAL2Hyaluronidase. (470 aa)
LOC102304771Hyaluronidase. (462 aa)
gmprGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (335 aa)
LOC102291647Uncharacterized protein. (101 aa)
LOC102312558Hyaluronidase. (543 aa)
LOC102294184NeuB domain-containing protein. (297 aa)
LOC102290730N-acetylneuraminic acid synthase a. (306 aa)
pcPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1155 aa)
LOC102299807Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (379 aa)
LOC102304959Triosephosphate isomerase. (247 aa)
aldocFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
dus4ltRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family. (315 aa)
ENSHBUP00000030000OMPdecase domain-containing protein. (315 aa)
nagaAlpha-galactosidase. (438 aa)
LOC102306995N-acetylneuraminic acid synthase b. (351 aa)
HYAL2-2Hyaluronidase. (477 aa)
LOC102312042Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (625 aa)
hmgcll13-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (341 aa)
LOC102308314Hyaluronidase. (462 aa)
hao2Hydroxyacid oxidase 2 (long chain). (379 aa)
rsad2Radical S-adenosyl methionine domain containing 2. (352 aa)
LOC102292801tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). (746 aa)
dhodhDihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (412 aa)
LOC102305459Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
dus3ltRNA-dihydrouridine(47) synthase [NAD(P)(+)]. (620 aa)
namptNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
dus2Dihydrouridine synthase 2. (498 aa)
naprtNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (556 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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