(116 nodes) Helicase superfamily 1/2, ATP-binding domain network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102304054	DEAD (Asp-Glu-Ala-Asp) box helicase 5; Belongs to the DEAD box helicase family. (624 aa)
	LOC102311462	Uncharacterized protein; Belongs to the DEAD box helicase family. (652 aa)
	DDX39A	DExD-box helicase 39A. (427 aa)
	ak8	RNA helicase. (866 aa)
	chd7	Chromodomain helicase DNA binding protein 7. (3316 aa)
	LOC102314191	Uncharacterized protein. (1505 aa)
	dicer1	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1906 aa)
	LOC102291041	Chromodomain helicase DNA binding protein 4a. (1861 aa)
	eif4a2	Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. (411 aa)
	chd2	Chromodomain helicase DNA binding protein 2. (1811 aa)
	LOC102308637	DEAD (Asp-Glu-Ala-Asp) box helicase 61; Belongs to the DEAD box helicase family. (477 aa)
	supv3l1	SUV3-like helicase. (784 aa)
	ddx21	DEAD (Asp-Glu-Ala-Asp) box helicase 21. (796 aa)
	dhx33	DEAH (Asp-Glu-Ala-His) box polypeptide 33. (681 aa)
	rad54b	RAD54 homolog B. (935 aa)
	blm	BLM RecQ like helicase. (1405 aa)
	chd4	Uncharacterized protein. (1812 aa)
	ddx56	DEAD (Asp-Glu-Ala-Asp) box helicase 56. (533 aa)
	eif4a3	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (406 aa)
	skiv2l	SKI2 homolog, superkiller viralicidic activity 2-like. (1242 aa)
	DDX17	DEAD-box helicase 17; Belongs to the DEAD box helicase family. (625 aa)
	ddx24	DEAD (Asp-Glu-Ala-Asp) box helicase 24. (870 aa)
	ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46. (1129 aa)
	smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1660 aa)
	ENSHBUP00000033440	Tudor domain containing 12. (983 aa)
	LOC102306769	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (817 aa)
	LOC102310951	Chromodomain helicase DNA binding protein 3. (2129 aa)
	rtel1	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1137 aa)
	dhx32	DEAH (Asp-Glu-Ala-His) box polypeptide 32a. (734 aa)
	ddx4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; Belongs to the DEAD box helicase family. (651 aa)
	dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58. (679 aa)
	helq	Helicase, POLQ like. (995 aa)
	polq	Polymerase (DNA directed), theta. (2129 aa)
	hells	Helicase, lymphoid specific. (854 aa)
	DDX5	DEAD-box helicase 5; Belongs to the DEAD box helicase family. (633 aa)
	SMARCAL1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (899 aa)
	ddx39a	Uncharacterized protein. (427 aa)
	ENSHBUP00000002926	ATRX chromatin remodeler, like. (1369 aa)
	btaf1	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated. (1859 aa)
	srcap	Snf2-related CREBBP activator protein. (4216 aa)
	ifih1	Interferon induced with helicase C domain 1. (992 aa)
	LOC102295839	Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family. (404 aa)
	dhx57	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57. (1435 aa)
	LOC102308009	DEAH (Asp-Glu-Ala-His) box helicase 15. (751 aa)
	LOC102303826	Uncharacterized protein. (1657 aa)
	dhx35	DEAH-box helicase 35. (699 aa)
	mtrex	Mtr4 exosome RNA helicase. (1037 aa)
	dhx29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1366 aa)
	smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1588 aa)
	ddx59	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59. (632 aa)
	fancm	Uncharacterized protein. (2114 aa)
	hfm1	Helicase for meiosis 1. (1050 aa)
	ddx51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51; Belongs to the DEAD box helicase family. (643 aa)
	rad54l	RAD54 like. (739 aa)
	ercc6l	Excision repair cross-complementation group 6-like. (1228 aa)
	ddx27	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27; Belongs to the DEAD box helicase family. (756 aa)
	UPF1	UPF1 RNA helicase and ATPase. (1004 aa)
	DHX15	DEAH-box helicase 15. (762 aa)
	ddx49	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49; Belongs to the DEAD box helicase family. (477 aa)
	ddx6	DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family. (481 aa)
	dhx16	DEAH (Asp-Glu-Ala-His) box polypeptide 16. (1007 aa)
	recql4	RecQ helicase-like 4. (1577 aa)
	ighmbp2	Immunoglobulin mu DNA binding protein 2. (981 aa)
	LOC102310286	DEAH (Asp-Glu-Ala-His) box polypeptide 32b. (740 aa)
	LOC102305453	Uncharacterized protein; Belongs to the DEAD box helicase family. (487 aa)
	ddx52	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52. (679 aa)
	zranb3	Zinc finger, RAN-binding domain containing 3. (1156 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1063 aa)
	ascc3	Activating signal cointegrator 1 complex subunit 3. (1581 aa)
	LOC102308233	Chromodomain helicase DNA binding protein 6. (3612 aa)
	ep400	E1A binding protein p400. (2908 aa)
	chd5	Chromodomain helicase DNA binding protein 5. (1804 aa)
	dhx38	DEAH (Asp-Glu-Ala-His) box polypeptide 38. (1259 aa)
	LOC102299406	RAD54 like 2. (1506 aa)
	ddx43	DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. (691 aa)
	atrx	ATRX chromatin remodeler. (1871 aa)
	recql	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (835 aa)
	LOC102302702	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast). (487 aa)
	LOC102299761	Uncharacterized protein. (903 aa)
	hltf	Helicase-like transcription factor. (968 aa)
	ddx1	DEAD (Asp-Glu-Ala-Asp) box helicase 1. (741 aa)
	dhx37	DEAH (Asp-Glu-Ala-His) box polypeptide 37. (1150 aa)
	shprh	SNF2 histone linker PHD RING helicase. (1661 aa)
	dqx1	DEAQ box RNA-dependent ATPase 1. (817 aa)
	ddx10	RNA helicase. (852 aa)
	ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (806 aa)
	DDX41	DEAD-box helicase 41. (614 aa)
	ddx55	RNA helicase. (590 aa)
	snrnp200	Small nuclear ribonucleoprotein 200 (U5). (1852 aa)
	smarcad1	Uncharacterized protein. (1053 aa)
	dhx34	DEAH (Asp-Glu-Ala-His) box polypeptide 34. (1142 aa)
	LOC102309101	Uncharacterized protein; Belongs to the DEAD box helicase family. (741 aa)
	smarca5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (790 aa)
	ddx42	DEAD (Asp-Glu-Ala-Asp) box helicase 42. (909 aa)
	ddx20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family. (792 aa)
	YTHDC2	YTH domain containing 2. (1207 aa)
	chd1l	Chromodomain helicase DNA binding protein 1-like. (994 aa)
	LOC102313919	Zgc:193690. (483 aa)
	chd1	Chromodomain helicase DNA binding protein 1. (1521 aa)
	dhx30	DEAH (Asp-Glu-Ala-His) box helicase 30. (1157 aa)
	dhx8	DEAH (Asp-Glu-Ala-His) box polypeptide 8. (1213 aa)
	ercc6l2	Excision repair cross-complementation group 6-like 2. (1535 aa)
	dhx9	DEAH (Asp-Glu-Ala-His) box helicase 9. (1271 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	ttf2	Transcription termination factor, RNA polymerase II. (1142 aa)
	chd8	Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2536 aa)
	ddx3x	DEAD-box helicase 3 X-linked a; Belongs to the DEAD box helicase family. (737 aa)
	LOC102312694	DEXH (Asp-Glu-X-His) box polypeptide 58. (679 aa)
	ddx18	RNA helicase. (652 aa)
	ercc6	Excision repair cross-complementation group 6. (1439 aa)
	ino80	INO80 complex ATPase subunit. (1497 aa)
	ddx28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28. (561 aa)
	dhx40	DEAH (Asp-Glu-Ala-His) box polypeptide 40. (740 aa)
	chd9	Chromodomain helicase DNA binding protein 9. (2898 aa)
	ddx47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47; Belongs to the DEAD box helicase family. (480 aa)
	LOC102293583	Uncharacterized protein. (270 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX17	DDX39A	ENSHBUP00000034592	ENSHBUP00000018177	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DExD-box helicase 39A.	0.591
DDX17	DDX41	ENSHBUP00000034592	ENSHBUP00000009406	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAD-box helicase 41.	0.640
DDX17	DHX15	ENSHBUP00000034592	ENSHBUP00000007425	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAH-box helicase 15.	0.786
DDX17	ENSHBUP00000002926	ENSHBUP00000034592	ENSHBUP00000002926	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	ATRX chromatin remodeler, like.	0.447
DDX17	LOC102291041	ENSHBUP00000034592	ENSHBUP00000016597	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Chromodomain helicase DNA binding protein 4a.	0.452
DDX17	LOC102293583	ENSHBUP00000034592	ENSHBUP00000019827	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.613
DDX17	LOC102299406	ENSHBUP00000034592	ENSHBUP00000028559	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	RAD54 like 2.	0.447
DDX17	LOC102299761	ENSHBUP00000034592	ENSHBUP00000012883	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.554
DDX17	LOC102302702	ENSHBUP00000034592	ENSHBUP00000000116	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast).	0.700
DDX17	LOC102303826	ENSHBUP00000034592	ENSHBUP00000004080	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.408
DDX17	LOC102306769	ENSHBUP00000034592	ENSHBUP00000033380	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.498
DDX17	LOC102308009	ENSHBUP00000034592	ENSHBUP00000003856	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAH (Asp-Glu-Ala-His) box helicase 15.	0.786
DDX17	LOC102308233	ENSHBUP00000034592	ENSHBUP00000029969	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Chromodomain helicase DNA binding protein 6.	0.447
DDX17	LOC102309101	ENSHBUP00000034592	ENSHBUP00000026703	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.628
DDX17	LOC102310286	ENSHBUP00000034592	ENSHBUP00000031557	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAH (Asp-Glu-Ala-His) box polypeptide 32b.	0.673
DDX17	LOC102310951	ENSHBUP00000034592	ENSHBUP00000033178	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Chromodomain helicase DNA binding protein 3.	0.452
DDX17	LOC102313919	ENSHBUP00000034592	ENSHBUP00000025023	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Zgc:193690.	0.700
DDX17	LOC102314191	ENSHBUP00000034592	ENSHBUP00000016941	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.447
DDX17	SMARCAL1	ENSHBUP00000034592	ENSHBUP00000001810	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.447
DDX17	UPF1	ENSHBUP00000034592	ENSHBUP00000007395	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	UPF1 RNA helicase and ATPase.	0.554