(11 nodes) CRIB domain superfamily network (Haplochromis burtoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pak5	Non-specific serine/threonine protein kinase. (782 aa)
	pak1	Non-specific serine/threonine protein kinase. (583 aa)
	pak6	Non-specific serine/threonine protein kinase. (698 aa)
	LOC102310290	CDC42 small effector 2. (76 aa)
	PAK3	Non-specific serine/threonine protein kinase. (575 aa)
	pak4	Non-specific serine/threonine protein kinase. (660 aa)
	LOC102307773	WASP like actin nucleation promoting factor a. (555 aa)
	LOC102294083	Uncharacterized protein. (552 aa)
	LOC102294556	Non-specific serine/threonine protein kinase. (513 aa)
	LOC102310773	Uncharacterized protein. (516 aa)
	ENSHBUP00000031317	P21 protein (Cdc42/Rac)-activated kinase 2b. (157 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000031317	LOC102294083	ENSHBUP00000031317	ENSHBUP00000027046	P21 protein (Cdc42/Rac)-activated kinase 2b.	Uncharacterized protein.	0.546
ENSHBUP00000031317	LOC102307773	ENSHBUP00000031317	ENSHBUP00000023707	P21 protein (Cdc42/Rac)-activated kinase 2b.	WASP like actin nucleation promoting factor a.	0.546
ENSHBUP00000031317	LOC102310773	ENSHBUP00000031317	ENSHBUP00000031008	P21 protein (Cdc42/Rac)-activated kinase 2b.	Uncharacterized protein.	0.546
ENSHBUP00000031317	PAK3	ENSHBUP00000031317	ENSHBUP00000020156	P21 protein (Cdc42/Rac)-activated kinase 2b.	Non-specific serine/threonine protein kinase.	0.877
ENSHBUP00000031317	pak1	ENSHBUP00000031317	ENSHBUP00000034780	P21 protein (Cdc42/Rac)-activated kinase 2b.	Non-specific serine/threonine protein kinase.	0.877
ENSHBUP00000031317	pak4	ENSHBUP00000031317	ENSHBUP00000022014	P21 protein (Cdc42/Rac)-activated kinase 2b.	Non-specific serine/threonine protein kinase.	0.828
ENSHBUP00000031317	pak5	ENSHBUP00000031317	ENSHBUP00000031516	P21 protein (Cdc42/Rac)-activated kinase 2b.	Non-specific serine/threonine protein kinase.	0.811
ENSHBUP00000031317	pak6	ENSHBUP00000031317	ENSHBUP00000014159	P21 protein (Cdc42/Rac)-activated kinase 2b.	Non-specific serine/threonine protein kinase.	0.529
LOC102294083	ENSHBUP00000031317	ENSHBUP00000027046	ENSHBUP00000031317	Uncharacterized protein.	P21 protein (Cdc42/Rac)-activated kinase 2b.	0.546
LOC102294083	LOC102294556	ENSHBUP00000027046	ENSHBUP00000029573	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.546
LOC102294083	PAK3	ENSHBUP00000027046	ENSHBUP00000020156	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.540
LOC102294083	pak1	ENSHBUP00000027046	ENSHBUP00000034780	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.540
LOC102294083	pak4	ENSHBUP00000027046	ENSHBUP00000022014	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.465
LOC102294083	pak5	ENSHBUP00000027046	ENSHBUP00000031516	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.465
LOC102294083	pak6	ENSHBUP00000027046	ENSHBUP00000014159	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.465
LOC102294556	LOC102294083	ENSHBUP00000029573	ENSHBUP00000027046	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.546
LOC102294556	LOC102307773	ENSHBUP00000029573	ENSHBUP00000023707	Non-specific serine/threonine protein kinase.	WASP like actin nucleation promoting factor a.	0.546
LOC102294556	LOC102310773	ENSHBUP00000029573	ENSHBUP00000031008	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.546
LOC102294556	PAK3	ENSHBUP00000029573	ENSHBUP00000020156	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.879
LOC102294556	pak1	ENSHBUP00000029573	ENSHBUP00000034780	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.879