STRINGSTRING
rfc1 rfc1 LOC102312405 LOC102312405 rfc2 rfc2 rfc5 rfc5 RPA1 RPA1 rfc3 rfc3 rev1 rev1 rps27a rps27a meiob meiob ENSHBUP00000001804 ENSHBUP00000001804 LOC102288768 LOC102288768 rpa1 rpa1 LOC102314666 LOC102314666 rpa3 rpa3 pcna pcna kxd1 kxd1 rpa2 rpa2 uba52 uba52 LOC102313827 LOC102313827 RCBTB1 RCBTB1 rfc4 rfc4 rev3l rev3l ubb ubb mad2l2 mad2l2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rfc1BRCT domain-containing protein. (471 aa)
LOC102312405ATPase family AAA domain containing 5a. (1808 aa)
rfc2Replication factor C (activator 1) 2. (356 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
rev1REV1 DNA directed polymerase. (1388 aa)
rps27aRibosomal protein S27a. (156 aa)
meiobMethionine sulfoxide reductase B1b. (464 aa)
ENSHBUP00000001804RFC1 domain-containing protein. (135 aa)
LOC102288768Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
rpa3Replication protein A3. (122 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
kxd1KxDL motif containing 1. (184 aa)
rpa2Replication protein A2. (293 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC102313827Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (591 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
rev3lREV3 like, DNA directed polymerase zeta catalytic subunit. (3016 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
mad2l2Mitotic arrest deficient 2 like 2. (253 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.