118 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBN1	Fibrillin 1. (2831 aa)
	LOC102305228	Uncharacterized protein. (857 aa)
	LOC102311902	Peptidylprolyl isomerase. (109 aa)
	LOC102292622	Mothers against decapentaplegic homolog. (510 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	ccnq	Cyclin Q; Belongs to the cyclin family. (254 aa)
	zfyve9	Zinc finger, FYVE domain containing 9a. (1194 aa)
	LOC102309987	Par-3 family cell polarity regulator alpha, b. (1409 aa)
	LOC102299619	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (303 aa)
	rbl1	Retinoblastoma-like 1 (p107). (1062 aa)
	LOC102312355	Mothers against decapentaplegic homolog. (606 aa)
	pard3b	Par-3 family cell polarity regulator beta a. (1279 aa)
	LOC102306247	Iroquois homeobox 7. (323 aa)
	itgb5	Integrin beta; Belongs to the integrin beta chain family. (803 aa)
	LOC102295185	Iroquois homeobox 4a. (473 aa)
	tfdp1	Transcription factor. (343 aa)
	ltbp1	Latent transforming growth factor beta binding protein 1. (1447 aa)
	ENSHBUP00000003450	Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1004 aa)
	LOC102307247	Par-6 family cell polarity regulator alpha. (414 aa)
	itgb3	Integrin beta; Belongs to the integrin beta chain family. (795 aa)
	cgn	Cingulin a. (1194 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	ENSHBUP00000001949	Ubiquitin-like domain-containing protein. (90 aa)
	LOC102296396	V-ski avian sarcoma viral oncogene homolog b. (686 aa)
	LOC102314283	Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
	prkcz	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
	LOC102301780	Meis_PKNOX_N domain-containing protein. (369 aa)
	PARD3	Par-3 family cell polarity regulator. (1373 aa)
	LOC102300579	F11 receptor, tandem duplicate 1. (298 aa)
	meis3	Myeloid ecotropic viral integration site 3. (420 aa)
	LOC102312159	Homeobox domain-containing protein. (577 aa)
	LTBP3	Latent transforming growth factor beta binding protein 3. (1214 aa)
	irx1	Iroquois homeobox 1b. (460 aa)
	cdk19	Cyclin-dependent kinase 19. (590 aa)
	ENSHBUP00000034204	GPS2_interact domain-containing protein. (207 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	LOC102296550	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (653 aa)
	itgb8	Integrin beta; Belongs to the integrin beta chain family. (803 aa)
	ldlrad4	Low density lipoprotein receptor class A domain containing 4b. (297 aa)
	sp1	Sp1 transcription factor. (707 aa)
	tgfb3	Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
	LOC102303111	Meis homeobox 1 b. (387 aa)
	cblc	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (601 aa)
	meis2	Meis homeobox 2a. (480 aa)
	ENSHBUP00000031626	Uncharacterized protein. (670 aa)
	LOC102314666	Ubiquitin-like domain-containing protein. (131 aa)
	LOC102310802	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (812 aa)
	LOC102307883	Cyclin T2b; Belongs to the cyclin family. (565 aa)
	ccnc	Cyclin C; Belongs to the cyclin family. (283 aa)
	usp9x	Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2523 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	ccnt1	Cyclin T1; Belongs to the cyclin family. (702 aa)
	LOC102305035	Meis homeobox 2b. (208 aa)
	ENSHBUP00000025655	Uncharacterized protein. (123 aa)
	LOC102304527	Mothers against decapentaplegic homolog. (467 aa)
	LOC102297158	Integrin beta; Belongs to the integrin beta chain family. (809 aa)
	bambi	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC102294386	Iroquois homeobox 1a. (495 aa)
	irx2	Iroquois homeobox 2a. (512 aa)
	itgb6	Integrin beta; Belongs to the integrin beta chain family. (782 aa)
	LOC102313119	Mohawk homeobox b. (416 aa)
	ski	V-ski avian sarcoma viral oncogene homolog a. (727 aa)
	SMURF2	SMAD specific E3 ubiquitin protein ligase 2. (668 aa)
	smurf1	E3 ubiquitin-protein ligase. (733 aa)
	STUB1	STIP1 homology and U-box containing protein 1. (290 aa)
	ncor2	Nuclear receptor corepressor 2. (2207 aa)
	snw1	SNW domain containing 1. (536 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (840 aa)
	cdk9	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
	e2f4	E2F transcription factor 4. (385 aa)
	ENSHBUP00000028658	MH1 domain-containing protein. (68 aa)
	rnf111	Ring finger protein 111. (1006 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	LOC102297985	NEDD8 ubiquitin like modifier. (91 aa)
	men1	Multiple endocrine neoplasia I. (542 aa)
	JUNB	JunB proto-oncogene, AP-1 transcription factor subunit a. (330 aa)
	LOC102309338	TGFB-induced factor homeobox 1. (309 aa)
	ccnk	Cyclin K; Belongs to the cyclin family. (539 aa)
	fkbp1b	Peptidylprolyl isomerase. (108 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
	atp1b4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (362 aa)
	LOC102302489	Mothers against decapentaplegic homolog. (375 aa)
	nedd4l	NEDD4 like E3 ubiquitin protein ligase. (1268 aa)
	ccnt2	Cyclin T2. (731 aa)
	smad7	Mothers against decapentaplegic homolog. (376 aa)
	cdk8	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
	ltbp2	Uncharacterized protein. (2080 aa)
	LOC102309614	Par-3 family cell polarity regulator beta b. (1044 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (538 aa)
	LOC102302192	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
	LOC102290591	JunB proto-oncogene, AP-1 transcription factor subunit b. (329 aa)
	LOC102297042	Peptidylprolyl isomerase. (108 aa)
	LOC102313422	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (546 aa)
	LOC102292487	Homeobox domain-containing protein. (362 aa)
	ENSHBUP00000019290	Uncharacterized protein. (890 aa)
	LOC102309260	Mothers against decapentaplegic homolog. (503 aa)
	ubb	Ubiquitin-like domain-containing protein. (54 aa)
	LOC102303022	Transcription factor jun-B-like. (330 aa)
	LOC102304566	E3 ubiquitin-protein ligase. (842 aa)
	LOC102292411	Homeobox domain-containing protein. (413 aa)
	pmepa1	Prostate transmembrane protein, androgen induced 1. (324 aa)
	smad2	Mothers against decapentaplegic homolog. (472 aa)
	ENSHBUP00000021196	Uncharacterized protein. (571 aa)
	irx3	Iroquois homeobox 3a. (422 aa)
	ENSHBUP00000021251	Uncharacterized protein. (416 aa)
	ENSHBUP00000021283	Uncharacterized protein. (196 aa)
	irx5	Iroquois homeobox 5a. (451 aa)
	ENSHBUP00000021329	Uncharacterized protein. (260 aa)
	irx6	Iroquois homeobox 6a. (509 aa)
	strap	Serine/threonine kinase receptor associated protein. (329 aa)
	mkx	Mohawk homeobox a. (375 aa)
	skil	SKI-like proto-oncogene a. (766 aa)
	stub1	STIP1 homology and U-Box containing protein 1. (284 aa)
	trim33	Tripartite motif containing 33. (1220 aa)
	LOC102314494	Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000001949	LOC102296550	ENSHBUP00000001949	ENSHBUP00000033349	Ubiquitin-like domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.667
ENSHBUP00000001949	LOC102304566	ENSHBUP00000001949	ENSHBUP00000019731	Ubiquitin-like domain-containing protein.	E3 ubiquitin-protein ligase.	0.603
ENSHBUP00000001949	LOC102305228	ENSHBUP00000001949	ENSHBUP00000010431	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.717
ENSHBUP00000001949	LOC102313422	ENSHBUP00000001949	ENSHBUP00000018960	Ubiquitin-like domain-containing protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.703
ENSHBUP00000001949	LOC102314666	ENSHBUP00000001949	ENSHBUP00000031002	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.912
ENSHBUP00000001949	SMURF2	ENSHBUP00000001949	ENSHBUP00000030043	Ubiquitin-like domain-containing protein.	SMAD specific E3 ubiquitin protein ligase 2.	0.603
ENSHBUP00000001949	STUB1	ENSHBUP00000001949	ENSHBUP00000029373	Ubiquitin-like domain-containing protein.	STIP1 homology and U-box containing protein 1.	0.497
ENSHBUP00000001949	TGFBR2	ENSHBUP00000001949	ENSHBUP00000017667	Ubiquitin-like domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.703
ENSHBUP00000001949	cbl	ENSHBUP00000001949	ENSHBUP00000015351	Ubiquitin-like domain-containing protein.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.717
ENSHBUP00000001949	cblc	ENSHBUP00000001949	ENSHBUP00000031845	Ubiquitin-like domain-containing protein.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.717
ENSHBUP00000001949	kxd1	ENSHBUP00000001949	ENSHBUP00000026699	Ubiquitin-like domain-containing protein.	KxDL motif containing 1.	0.563
ENSHBUP00000001949	ldlrad4	ENSHBUP00000001949	ENSHBUP00000033176	Ubiquitin-like domain-containing protein.	Low density lipoprotein receptor class A domain containing 4b.	0.408
ENSHBUP00000001949	nedd4l	ENSHBUP00000001949	ENSHBUP00000015760	Ubiquitin-like domain-containing protein.	NEDD4 like E3 ubiquitin protein ligase.	0.565
ENSHBUP00000001949	parp1	ENSHBUP00000001949	ENSHBUP00000008939	Ubiquitin-like domain-containing protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.454
ENSHBUP00000001949	pmepa1	ENSHBUP00000001949	ENSHBUP00000020286	Ubiquitin-like domain-containing protein.	Prostate transmembrane protein, androgen induced 1.	0.408
ENSHBUP00000001949	rbl1	ENSHBUP00000001949	ENSHBUP00000006670	Ubiquitin-like domain-containing protein.	Retinoblastoma-like 1 (p107).	0.464
ENSHBUP00000001949	rnf111	ENSHBUP00000001949	ENSHBUP00000028614	Ubiquitin-like domain-containing protein.	Ring finger protein 111.	0.542
ENSHBUP00000001949	rps27a	ENSHBUP00000001949	ENSHBUP00000002167	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.957
ENSHBUP00000001949	smurf1	ENSHBUP00000001949	ENSHBUP00000029443	Ubiquitin-like domain-containing protein.	E3 ubiquitin-protein ligase.	0.603
ENSHBUP00000001949	stub1	ENSHBUP00000001949	ENSHBUP00000011770	Ubiquitin-like domain-containing protein.	STIP1 homology and U-Box containing protein 1.	0.512