44 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	egf	Epidermal growth factor. (1159 aa)
	ENSHBUP00000001041	Tyrosine-protein phosphatase domain-containing protein. (276 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (752 aa)
	LOC102301399	Rho guanine nucleotide exchange factor (GEF) 7a. (802 aa)
	btc	Betacellulin, epidermal growth factor family member. (172 aa)
	eps15l1	Epidermal growth factor receptor pathway substrate 15-like 1a. (968 aa)
	PTPRM	Protein tyrosine phosphatase receptor type M. (1455 aa)
	CDC42	Cell division cycle 42. (191 aa)
	sh3d21	SH3 domain containing 21. (497 aa)
	stam2	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2. (517 aa)
	LOC102305228	Uncharacterized protein. (857 aa)
	stam	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (751 aa)
	LOC102294469	Uncharacterized protein. (191 aa)
	sh3kbp1	Uncharacterized protein. (745 aa)
	ENSHBUP00000013287	MAM domain-containing protein. (143 aa)
	LOC102302082	Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (209 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
	LOC102288700	Uncharacterized protein. (172 aa)
	ptprt	Protein tyrosine phosphatase receptor type T. (1504 aa)
	spry2	Sprouty RTK signaling antagonist 2. (333 aa)
	spry1	Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (360 aa)
	sh3gl1	SH3-domain GRB2-like 1a. (369 aa)
	ubb	Ubiquitin-like domain-containing protein. (54 aa)
	LOC102305789	Transforming growth factor, alpha. (254 aa)
	LOC102293456	SH3-domain GRB2-like 3a. (324 aa)
	ptprk	Protein tyrosine phosphatase receptor type K. (1479 aa)
	LOC102291569	SH3-domain GRB2-like 1b. (363 aa)
	LOC102311613	Cell division cycle 42. (191 aa)
	sh3gl2	SH3 domain containing GRB2 like 2a, endophilin A1. (363 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC102288968	Epithelial mitogen homolog (mouse). (164 aa)
	LOC102289283	EGF-like domain-containing protein. (154 aa)
	ENSHBUP00000028858	Epidermal growth factor receptor pathway substrate 15 like 1. (543 aa)
	SPRY3	Sprouty RTK signaling antagonist 3. (286 aa)
	ptpn3	Protein tyrosine phosphatase non-receptor type 3. (874 aa)
	LOC102307526	Uncharacterized protein. (191 aa)
	LOC102306701	Rho guanine nucleotide exchange factor (GEF) 7b. (850 aa)
	LOC102314666	Ubiquitin-like domain-containing protein. (131 aa)
	cblc	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (601 aa)
	LOC102314603	Uncharacterized protein. (184 aa)
	eps15	Epidermal growth factor receptor pathway substrate 15. (1093 aa)
	LOC102308269	Uncharacterized protein. (351 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSHBUP00000028858	ENSHBUP00000007818	ENSHBUP00000028858	Cell division cycle 42.	Epidermal growth factor receptor pathway substrate 15 like 1.	0.404
CDC42	LOC102288700	ENSHBUP00000007818	ENSHBUP00000016530	Cell division cycle 42.	Uncharacterized protein.	0.528
CDC42	LOC102289283	ENSHBUP00000007818	ENSHBUP00000028216	Cell division cycle 42.	EGF-like domain-containing protein.	0.683
CDC42	LOC102294469	ENSHBUP00000007818	ENSHBUP00000011761	Cell division cycle 42.	Uncharacterized protein.	0.523
CDC42	LOC102301399	ENSHBUP00000007818	ENSHBUP00000004231	Cell division cycle 42.	Rho guanine nucleotide exchange factor (GEF) 7a.	0.828
CDC42	LOC102302082	ENSHBUP00000007818	ENSHBUP00000013847	Cell division cycle 42.	Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family.	0.423
CDC42	LOC102305228	ENSHBUP00000007818	ENSHBUP00000010431	Cell division cycle 42.	Uncharacterized protein.	0.675
CDC42	LOC102305789	ENSHBUP00000007818	ENSHBUP00000020092	Cell division cycle 42.	Transforming growth factor, alpha.	0.638
CDC42	LOC102306701	ENSHBUP00000007818	ENSHBUP00000030866	Cell division cycle 42.	Rho guanine nucleotide exchange factor (GEF) 7b.	0.828
CDC42	LOC102307526	ENSHBUP00000007818	ENSHBUP00000030785	Cell division cycle 42.	Uncharacterized protein.	0.523
CDC42	LOC102314603	ENSHBUP00000007818	ENSHBUP00000032301	Cell division cycle 42.	Uncharacterized protein.	0.531
CDC42	LOC102314666	ENSHBUP00000007818	ENSHBUP00000031002	Cell division cycle 42.	Ubiquitin-like domain-containing protein.	0.746
CDC42	cbl	ENSHBUP00000007818	ENSHBUP00000015351	Cell division cycle 42.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.675
CDC42	cblc	ENSHBUP00000007818	ENSHBUP00000031845	Cell division cycle 42.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.675
CDC42	egf	ENSHBUP00000007818	ENSHBUP00000000026	Cell division cycle 42.	Epidermal growth factor.	0.732
CDC42	eps15	ENSHBUP00000007818	ENSHBUP00000033592	Cell division cycle 42.	Epidermal growth factor receptor pathway substrate 15.	0.404
CDC42	eps15l1	ENSHBUP00000007818	ENSHBUP00000006080	Cell division cycle 42.	Epidermal growth factor receptor pathway substrate 15-like 1a.	0.404
CDC42	grb2	ENSHBUP00000007818	ENSHBUP00000034295	Cell division cycle 42.	Growth factor receptor-bound protein 2b.	0.806
CDC42	hgs	ENSHBUP00000007818	ENSHBUP00000003610	Cell division cycle 42.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.576
CDC42	rps27a	ENSHBUP00000007818	ENSHBUP00000002167	Cell division cycle 42.	Ribosomal protein S27a.	0.730