STRINGSTRING
fgf2 fgf2 LOC102304742 LOC102304742 fgf22 fgf22 LOC102307281 LOC102307281 LOC102289294 LOC102289294 fgf3 fgf3 fgf10 fgf10 LOC102296557 LOC102296557 LOC102292008 LOC102292008
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC102304742Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
LOC102307281Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
LOC102289294Fibroblast growth factor receptor. (836 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
LOC102296557Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
LOC102292008Uncharacterized protein. (458 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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