STRINGSTRING
gab2 gab2 fgf16 fgf16 LOC106633073 LOC106633073 LOC102296557 LOC102296557 LOC102306688 LOC102306688 LOC102303940 LOC102303940 pik3ca pik3ca ENSHBUP00000003732 ENSHBUP00000003732 ENSHBUP00000003882 ENSHBUP00000003882 kl kl ENSHBUP00000005111 ENSHBUP00000005111 igf1 igf1 fgf23 fgf23 fgfr2 fgfr2 ENSHBUP00000009952 ENSHBUP00000009952 fgf10 fgf10 fgf7 fgf7 lctl lctl FGF6 FGF6 LOC102300437 LOC102300437 fgf3 fgf3 LOC102302326 LOC102302326 fgf4 fgf4 fgf19 fgf19 FGF13 FGF13 LOC102307281 LOC102307281 LOC102297727 LOC102297727 LOC102291075 LOC102291075 LOC102310436 LOC102310436 LOC102309911 LOC102309911 fgf2 fgf2 ENSHBUP00000019390 ENSHBUP00000019390 LOC102304742 LOC102304742 pik3cb pik3cb LOC102297386 LOC102297386 LOC102300439 LOC102300439 pdpk1 pdpk1 LOC102305144 LOC102305144 fgf5 fgf5 LOC102314346 LOC102314346 LOC102312030 LOC102312030 klb klb fgf18 fgf18 gab1 gab1 fgf22 fgf22 LOC102291452 LOC102291452 FGF6-2 FGF6-2 LOC102289393 LOC102289393 LOC102291222 LOC102291222 LOC102289294 LOC102289294 LOC102311744 LOC102311744 LOC102304610 LOC102304610 pde3b pde3b fgf20 fgf20 LOC102304410 LOC102304410 LOC102295844 LOC102295844 LOC102292008 LOC102292008 fgfr4 fgfr4 fgf8 fgf8 LOC102312349 LOC102312349 LOC102311290 LOC102311290 ENSHBUP00000034273 ENSHBUP00000034273 grb2 grb2 LOC102297192 LOC102297192 igf2 igf2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gab2GRB2-associated binding protein 2. (654 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC106633073Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC102296557Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
LOC102306688Si:ch211-284e13.4. (1165 aa)
LOC102303940Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSHBUP00000003732Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (373 aa)
ENSHBUP00000003882Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (441 aa)
klKlotho. (978 aa)
ENSHBUP00000005111Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
igf1Insulin-like growth factor 1. (182 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)
fgfr2Fibroblast growth factor receptor. (835 aa)
ENSHBUP00000009952PH domain-containing protein. (146 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
lctlLactase-like b; Belongs to the glycosyl hydrolase 1 family. (585 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC102300437Uncharacterized protein. (248 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
LOC102302326Lactase-like a; Belongs to the glycosyl hydrolase 1 family. (574 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
LOC102307281Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
LOC102297727Tyrosine-protein kinase receptor. (1341 aa)
LOC102291075Fibroblast growth factor receptor. (709 aa)
LOC102310436Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC102309911Insulin receptor substrate 4a. (1402 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
ENSHBUP00000019390Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (284 aa)
LOC102304742Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
LOC102297386Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
LOC102300439Thioesterase superfamily member 4. (249 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (565 aa)
LOC102305144Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (666 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
LOC102314346Insulin receptor substrate 2a. (1086 aa)
LOC102312030Fibroblast growth factor receptor substrate 2b. (525 aa)
klbKlotho beta. (1049 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
gab1GRB2-associated binding protein 1. (746 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
LOC102291452Fibroblast growth factor receptor. (818 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC102289393PH domain-containing protein. (543 aa)
LOC102291222Insulin receptor substrate 2b. (1160 aa)
LOC102289294Fibroblast growth factor receptor. (836 aa)
LOC102311744Tribbles pseudokinase 3. (353 aa)
LOC102304610Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
pde3bPhosphodiesterase. (1099 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
LOC102304410Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102295844Si:ch73-335l21.1. (1276 aa)
LOC102292008Uncharacterized protein. (458 aa)
fgfr4Fibroblast growth factor receptor 4. (945 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (226 aa)
LOC102312349Tyrosine-protein kinase receptor. (1417 aa)
LOC102311290Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (594 aa)
ENSHBUP00000034273Zgc:158659; Belongs to the PI3/PI4-kinase family. (485 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC102297192Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
igf2Insulin-like growth factor 2b. (215 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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