STRINGSTRING
LOC102296990 LOC102296990 ppp2r5e ppp2r5e LOC102290331 LOC102290331 LOC102291828 LOC102291828 NDE1 NDE1 dync1i2 dync1i2 zw10 zw10 incenp incenp ENSHBUP00000032296 ENSHBUP00000032296 ENSHBUP00000032172 ENSHBUP00000032172 LOC102301386 LOC102301386 mad1l1 mad1l1 rangap1 rangap1 LOC102292971 LOC102292971 LOC102312232 LOC102312232 DYNLL2 DYNLL2 ppp2r5b ppp2r5b smc3 smc3 pafah1b1 pafah1b1 LOC102298609 LOC102298609 LOC102300262 LOC102300262 clip2 clip2 LOC102293752 LOC102293752 ccnb2 ccnb2 LOC102300272 LOC102300272 cenph cenph kif2a kif2a ccnb1 ccnb1 cdc20b cdc20b ENSHBUP00000028033 ENSHBUP00000028033 LOC102290810 LOC102290810 ENSHBUP00000027889 ENSHBUP00000027889 nup43 nup43 LOC102311631 LOC102311631 LOC106632284 LOC106632284 ENSHBUP00000027143 ENSHBUP00000027143 nudc nudc ndc80 ndc80 ENSHBUP00000026004 ENSHBUP00000026004 clip1 clip1 mapre2 mapre2 LOC102291296 LOC102291296 stag3 stag3 xpo1 xpo1 nup133 nup133 LOC102291667 LOC102291667 tubb4b tubb4b LOC102301011 LOC102301011 sec13 sec13 LOC102295499 LOC102295499 ska1 ska1 ercc6l2 ercc6l2 LOC102295920 LOC102295920 LOC102296237 LOC102296237 smc1a smc1a cdc20 cdc20 LOC102307802 LOC102307802 ranbp2 ranbp2 dync1li2 dync1li2 LOC102301096 LOC102301096 LOC102301689 LOC102301689 ENSHBUP00000021812 ENSHBUP00000021812 ENSHBUP00000021794 ENSHBUP00000021794 LOC102298446 LOC102298446 cdca8 cdca8 clasp1 clasp1 PPP2R5C PPP2R5C nuf2 nuf2 RAD21 RAD21 KIF18A KIF18A ccnb3 ccnb3 ENSHBUP00000020359 ENSHBUP00000020359 LOC102310296 LOC102310296 cntd2 cntd2 tube1 tube1 spc24 spc24 ppp2ca ppp2ca ENSHBUP00000018665 ENSHBUP00000018665 seh1l seh1l rcc2 rcc2 cenpk cenpk LOC102314172 LOC102314172 ENSHBUP00000017345 ENSHBUP00000017345 bub3 bub3 DYNC1I1 DYNC1I1 cenpf cenpf clasp2 clasp2 mis12 mis12 ENSHBUP00000016099 ENSHBUP00000016099 ENSHBUP00000016048 ENSHBUP00000016048 LOC102289121 LOC102289121 ppp2r5a ppp2r5a LOC102293174 LOC102293174 tubb tubb LOC102291664 LOC102291664 LOC102303125 LOC102303125 ska2 ska2 LOC102304191 LOC102304191 cenpn cenpn bub1b bub1b cenpi cenpi stag1 stag1 ENSHBUP00000012738 ENSHBUP00000012738 cdk1 cdk1 LOC102291619 LOC102291619 LOC102309330 LOC102309330 LOC102310672 LOC102310672 LOC102313370 LOC102313370 zwilch zwilch LOC102289767 LOC102289767 LOC102298344 LOC102298344 hdac8 hdac8 knl1 knl1 ENSHBUP00000010021 ENSHBUP00000010021 LOC102292095 LOC102292095 LOC102310266 LOC102310266 nup85 nup85 LOC102310614 LOC102310614 ENSHBUP00000008928 ENSHBUP00000008928 LOC102314123 LOC102314123 LOC102304439 LOC102304439 ENSHBUP00000007972 ENSHBUP00000007972 ENSHBUP00000007964 ENSHBUP00000007964 LOC102288730 LOC102288730 ckap5 ckap5 wapl wapl ENSHBUP00000007378 ENSHBUP00000007378 ENSHBUP00000007056 ENSHBUP00000007056 LOC102311436 LOC102311436 ppp2r5d ppp2r5d ercc6l ercc6l ENSHBUP00000006166 ENSHBUP00000006166 kntc1 kntc1 nup160 nup160 TUBA1A TUBA1A pds5b pds5b wdr41 wdr41 ppp2cb ppp2cb spc25 spc25 spdl1 spdl1 LOC102305679 LOC102305679 cenpm cenpm LOC102294619 LOC102294619 nsl1 nsl1 nup107 nup107 LOC102295711 LOC102295711 sgo1 sgo1 LOC102307592 LOC102307592 LOC102301505 LOC102301505 pds5a pds5a ENSHBUP00000001407 ENSHBUP00000001407 ENSHBUP00000001388 ENSHBUP00000001388 LOC102299544 LOC102299544 LOC102308588 LOC102308588 meioc meioc LOC102290684 LOC102290684 bub1 bub1 cdca5 cdca5 ppp1cc ppp1cc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102296990Exportin 1 (CRM1 homolog, yeast) b. (1071 aa)
ppp2r5eSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (478 aa)
LOC102290331Baculoviral IAP repeat containing 5a. (142 aa)
LOC102291828TAO kinase 1b. (1013 aa)
NDE1NudE neurodevelopment protein 1. (315 aa)
dync1i2Dynein, cytoplasmic 1, intermediate chain 2a. (623 aa)
zw10Zw10 kinetochore protein. (766 aa)
incenpUncharacterized protein. (837 aa)
ENSHBUP00000032296Uncharacterized protein. (134 aa)
ENSHBUP00000032172Uncharacterized protein. (108 aa)
LOC102301386Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
mad1l1Mitotic arrest deficient 1 like 1. (672 aa)
rangap1RAN GTPase activating protein 1a. (552 aa)
LOC102292971Microtubule-associated protein, RP/EB family, member 3a. (262 aa)
LOC102312232CENP-C_C domain-containing protein. (1033 aa)
DYNLL2Dynein light chain. (89 aa)
ppp2r5bSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (522 aa)
smc3Structural maintenance of chromosomes protein. (1217 aa)
pafah1b1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
LOC102298609Dynein light chain. (89 aa)
LOC102300262Dynein, cytoplasmic 1, intermediate chain 2b. (634 aa)
clip2CAP-GLY domain containing linker protein 2. (1015 aa)
LOC102293752Dynein light chain. (89 aa)
ccnb2Cyclin B2; Belongs to the cyclin family. (388 aa)
LOC102300272Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (707 aa)
cenphCENP-H domain-containing protein. (268 aa)
kif2aKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (760 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (402 aa)
cdc20bWD_REPEATS_REGION domain-containing protein. (366 aa)
ENSHBUP00000028033Uncharacterized protein. (319 aa)
LOC102290810Uncharacterized protein. (1433 aa)
ENSHBUP00000027889B9 domain containing 2. (152 aa)
nup43Nucleoporin 43. (372 aa)
LOC102311631Si:dkey-6i22.5. (226 aa)
LOC106632284Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (433 aa)
ENSHBUP00000027143AIG1-type G domain-containing protein. (504 aa)
nudcNudC nuclear distribution protein. (332 aa)
ndc80NDC80 kinetochore complex component. (639 aa)
ENSHBUP00000026004Tubulin_C domain-containing protein. (122 aa)
clip1CAP-GLY domain containing linker protein 1a. (2225 aa)
mapre2Microtubule-associated protein, RP/EB family, member 2. (338 aa)
LOC102291296Selenoprotein H. (120 aa)
stag3SCD domain-containing protein. (1191 aa)
xpo1Exportin 1 (CRM1 homolog, yeast) a. (1066 aa)
nup133Nucleoporin 133. (1135 aa)
LOC102291667Aurora kinase B; Belongs to the protein kinase superfamily. (305 aa)
tubb4bTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
LOC102301011Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (325 aa)
sec13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (331 aa)
LOC102295499Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
ska1Spindle and kinetochore associated complex subunit 1. (245 aa)
ercc6l2Excision repair cross-complementation group 6-like 2. (1535 aa)
LOC102295920NudE neurodevelopment protein 1-like 1a. (343 aa)
LOC102296237Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
smc1aStructural maintenance of chromosomes protein. (1231 aa)
cdc20Cell division cycle 20 homolog. (542 aa)
LOC102307802Stromal antigen 2b. (1249 aa)
ranbp2RAN binding protein 2. (3058 aa)
dync1li2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
LOC102301096Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
LOC102301689Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (434 aa)
ENSHBUP00000021812Uncharacterized protein. (899 aa)
ENSHBUP00000021794Uncharacterized protein. (347 aa)
LOC102298446Uncharacterized protein. (273 aa)
cdca8Cell division cycle associated 8. (279 aa)
clasp1Cytoplasmic linker associated protein 1a. (1430 aa)
PPP2R5CSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (532 aa)
nuf2UF2 component of NDC80 kinetochore complex. (436 aa)
RAD21RAD21 cohesin complex component. (648 aa)
KIF18AKinesin family member 18A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (751 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (408 aa)
ENSHBUP00000020359Tubulin_C domain-containing protein. (187 aa)
LOC102310296Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (578 aa)
cntd2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (361 aa)
tube1Tubulin, epsilon 1; Belongs to the tubulin family. (474 aa)
spc24SPC24 component of NDC80 kinetochore complex. (199 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
ENSHBUP00000018665Uncharacterized protein. (196 aa)
seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (351 aa)
rcc2Regulator of chromosome condensation 2. (494 aa)
cenpkCentromere protein K. (262 aa)
LOC102314172Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (485 aa)
ENSHBUP00000017345AT hook containing transcription factor 1. (1859 aa)
bub3BUB3 mitotic checkpoint protein. (326 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (571 aa)
cenpfCentromere protein F. (2259 aa)
clasp2Cytoplasmic linker associated protein 2. (1208 aa)
mis12MIS12 kinetochore complex component. (231 aa)
ENSHBUP00000016099Peptidase S59 domain-containing protein. (193 aa)
ENSHBUP00000016048Uncharacterized protein. (505 aa)
LOC102289121TAO kinase 1a. (1021 aa)
ppp2r5aSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (511 aa)
LOC102293174Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
tubbTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
LOC102291664Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
LOC102303125Uncharacterized protein. (379 aa)
ska2Spindle and kinetochore associated complex subunit 2. (224 aa)
LOC102304191Structural maintenance of chromosomes protein. (1245 aa)
cenpnCentromere protein N. (348 aa)
bub1bBUB1 mitotic checkpoint serine/threonine kinase Bb. (426 aa)
cenpiCentromere protein I. (733 aa)
stag1Stromal antigen 1a. (1260 aa)
ENSHBUP00000012738Uncharacterized protein. (295 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (307 aa)
LOC102291619Microtubule-associated protein, RP/EB family, member 3b. (274 aa)
LOC102309330Microtubule-associated protein, RP/EB family, member 1b. (258 aa)
LOC102310672Calponin-homology (CH) domain-containing protein. (162 aa)
LOC102313370WAPL cohesin release factor b. (1213 aa)
zwilchZwilch kinetochore protein. (609 aa)
LOC102289767RAD21 cohesin complex component a. (636 aa)
LOC102298344Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
hdac8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (379 aa)
knl1Knl1_RWD_C domain-containing protein. (1829 aa)
ENSHBUP00000010021Uncharacterized protein. (122 aa)
LOC102292095Si:ch211-269e2.1. (1091 aa)
LOC102310266RAD21 cohesin complex component like 1. (547 aa)
nup85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (540 aa)
LOC102310614Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ENSHBUP00000008928AIG1-type G domain-containing protein. (512 aa)
LOC102314123Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC102304439Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (332 aa)
ENSHBUP00000007972Uncharacterized protein. (985 aa)
ENSHBUP00000007964Uncharacterized protein. (389 aa)
LOC102288730Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (484 aa)
ckap5Cytoskeleton associated protein 5. (1599 aa)
waplWAPL cohesin release factor a. (1171 aa)
ENSHBUP00000007378Tubulin domain-containing protein. (155 aa)
ENSHBUP00000007056Nucleoporin 37. (313 aa)
LOC102311436Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (398 aa)
ppp2r5dSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (569 aa)
ercc6lExcision repair cross-complementation group 6-like. (1228 aa)
ENSHBUP00000006166Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (154 aa)
kntc1Kinetochore associated 1. (2083 aa)
nup160Nucleoporin 160. (1289 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
pds5bPDS5 cohesin associated factor B. (1409 aa)
wdr41WD repeat domain 41. (450 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
spc25SPC25 component of NDC80 kinetochore complex. (236 aa)
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (574 aa)
LOC102305679Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
cenpmProliferation associated nuclear element. (184 aa)
LOC102294619NudE neurodevelopment protein 1-like 1b. (340 aa)
nsl1NSL1 component of MIS12 kinetochore complex. (258 aa)
nup107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (908 aa)
LOC102295711Baculoviral IAP repeat containing 5b. (144 aa)
sgo1Shugoshin_C domain-containing protein. (718 aa)
LOC102307592Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (367 aa)
LOC102301505Stromal antigen 2a. (1276 aa)
pds5aPDS5 cohesin associated factor A. (1294 aa)
ENSHBUP00000001407Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (256 aa)
ENSHBUP00000001388Tubulin domain-containing protein. (87 aa)
LOC102299544Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
LOC102308588Centromere protein S. (123 aa)
meiocMinamoto. (797 aa)
LOC102290684Serine/threonine-protein phosphatase. (309 aa)
bub1BUB1 mitotic checkpoint serine/threonine kinase. (1199 aa)
cdca5Cell division cycle associated 5. (260 aa)
ppp1ccSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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