41 items (Haplochromis burtoni) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	LOC106633073	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC102296557	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
	LOC102303940	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
	ENSHBUP00000005111	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	LOC102289587	DDE_Tnp_1_7 domain-containing protein. (578 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)
	LOC102309641	Fibroblast growth factor receptor substrate 3. (613 aa)
	fgf10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
	SHC4	SHC adaptor protein 4. (588 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
	LOC102307281	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
	LOC102307400	Zgc:55558. (187 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (922 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	ENSHBUP00000019390	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (284 aa)
	LOC102304742	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
	fgf5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
	LOC102312030	Fibroblast growth factor receptor substrate 2b. (525 aa)
	gab1	GRB2-associated binding protein 1. (746 aa)
	fgf22	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	FGF6-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC102289393	PH domain-containing protein. (543 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	flrt1	Fibronectin leucine rich transmembrane protein 1b. (733 aa)
	flrt2	Fibronectin leucine rich transmembrane protein 2. (660 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (217 aa)
	LOC102289294	Fibroblast growth factor receptor. (836 aa)
	ENSHBUP00000008412	DDE_Tnp_1_7 domain-containing protein. (441 aa)
	LOC102304610	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
	fgf20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	LOC102304410	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC102292008	Uncharacterized protein. (458 aa)
	LOC102302053	Fibronectin leucine rich transmembrane protein 1. (684 aa)
	flrt3	Fibronectin leucine rich transmembrane 3. (650 aa)
	ENSHBUP00000034273	Zgc:158659; Belongs to the PI3/PI4-kinase family. (485 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSHBUP00000005111	ENSHBUP00000018081	ENSHBUP00000005111	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.550
CSDE1	ENSHBUP00000019390	ENSHBUP00000018081	ENSHBUP00000019390	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.723
CSDE1	ENSHBUP00000034273	ENSHBUP00000018081	ENSHBUP00000034273	Cold shock domain containing E1, RNA-binding.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.723
CSDE1	LOC102289294	ENSHBUP00000018081	ENSHBUP00000029158	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor.	0.625
CSDE1	LOC102289393	ENSHBUP00000018081	ENSHBUP00000028120	Cold shock domain containing E1, RNA-binding.	PH domain-containing protein.	0.487
CSDE1	LOC102292008	ENSHBUP00000018081	ENSHBUP00000032940	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.625
CSDE1	LOC102296557	ENSHBUP00000018081	ENSHBUP00000000782	Cold shock domain containing E1, RNA-binding.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.528
CSDE1	LOC102303940	ENSHBUP00000018081	ENSHBUP00000002371	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.545
CSDE1	LOC102304410	ENSHBUP00000018081	ENSHBUP00000031887	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.723
CSDE1	LOC102304610	ENSHBUP00000018081	ENSHBUP00000029550	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.566
CSDE1	LOC102304742	ENSHBUP00000018081	ENSHBUP00000019944	Cold shock domain containing E1, RNA-binding.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.528
CSDE1	LOC102307281	ENSHBUP00000018081	ENSHBUP00000013895	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.419
CSDE1	LOC102309641	ENSHBUP00000018081	ENSHBUP00000009195	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 3.	0.556
CSDE1	LOC102312030	ENSHBUP00000018081	ENSHBUP00000025416	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 2b.	0.556
CSDE1	LOC106633073	ENSHBUP00000018081	ENSHBUP00000000711	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.418
CSDE1	SHC4	ENSHBUP00000018081	ENSHBUP00000010980	Cold shock domain containing E1, RNA-binding.	SHC adaptor protein 4.	0.513
CSDE1	fgf10	ENSHBUP00000018081	ENSHBUP00000010642	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.419
CSDE1	fgf20	ENSHBUP00000018081	ENSHBUP00000031478	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.418
CSDE1	fgf22	ENSHBUP00000018081	ENSHBUP00000027028	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.419
CSDE1	fgf23	ENSHBUP00000018081	ENSHBUP00000008916	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.578