STRINGSTRING
FGF6 FGF6 CSDE1 CSDE1 LOC102307400 LOC102307400 LOC102307281 LOC102307281 fgf4 fgf4 fgf3 fgf3 LOC102304742 LOC102304742 fgf2 fgf2 shc1 shc1 fgf5 fgf5 fgf22 fgf22 FGF6-2 FGF6-2 hras hras KRAS KRAS LOC102289294 LOC102289294 LOC102304610 LOC102304610 fgf20 fgf20 LOC102292008 LOC102292008 LOC106633073 LOC106633073 LOC102296557 LOC102296557 grb2 grb2 LOC102303940 LOC102303940 ENSHBUP00000005111 ENSHBUP00000005111 LOC102289587 LOC102289587 ENSHBUP00000008412 ENSHBUP00000008412 fgf23 fgf23 fgf10 fgf10 SHC4 SHC4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (922 aa)
LOC102307400Zgc:55558. (187 aa)
LOC102307281Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
LOC102304742Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (217 aa)
LOC102289294Fibroblast growth factor receptor. (836 aa)
LOC102304610Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
LOC102292008Uncharacterized protein. (458 aa)
LOC106633073Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC102296557Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC102303940Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
ENSHBUP00000005111Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
LOC102289587DDE_Tnp_1_7 domain-containing protein. (578 aa)
ENSHBUP00000008412DDE_Tnp_1_7 domain-containing protein. (441 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
SHC4SHC adaptor protein 4. (588 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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