STRINGSTRING
spry2 spry2 LOC102291388 LOC102291388 LOC106633073 LOC106633073 LOC102296557 LOC102296557 LOC102290684 LOC102290684 rps27a rps27a SRC SRC LOC102303940 LOC102303940 mknk2 mknk2 ppp2cb ppp2cb ENSHBUP00000005111 ENSHBUP00000005111 LOC102313431 LOC102313431 LOC102296758 LOC102296758 fgf23 fgf23 LOC102305228 LOC102305228 fgf10 fgf10 FGF6 FGF6 fgf3 fgf3 fgf4 fgf4 fndc3b fndc3b LOC102307281 LOC102307281 cbl cbl fgf2 fgf2 LOC102302192 LOC102302192 ppp2ca ppp2ca ubb ubb LOC102304742 LOC102304742 ANOS1 ANOS1 fndc3a fndc3a fgf5 fgf5 mapk1 mapk1 LOC102312030 LOC102312030 uba52 uba52 fgf22 fgf22 FGF6-2 FGF6-2 LOC102289294 LOC102289294 LOC102304610 LOC102304610 SPRY3 SPRY3 LOC102289408 LOC102289408 LOC102314666 LOC102314666 fgf20 fgf20 cblc cblc LOC102301386 LOC102301386 LOC102292008 LOC102292008 grb2 grb2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
spry2Sprouty RTK signaling antagonist 2. (333 aa)
LOC102291388Uncharacterized protein. (613 aa)
LOC106633073Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC102296557Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
LOC102290684Serine/threonine-protein phosphatase. (309 aa)
rps27aRibosomal protein S27a. (156 aa)
SRCTyrosine-protein kinase. (550 aa)
LOC102303940Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
ENSHBUP00000005111Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
LOC102313431MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (462 aa)
LOC102296758Tyrosine-protein kinase. (590 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)
LOC102305228Uncharacterized protein. (857 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
fndc3bFibronectin type III domain containing 3Ba. (1204 aa)
LOC102307281Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC102302192Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
LOC102304742Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
ANOS1Anosmin 1. (673 aa)
fndc3aFibronectin type III domain containing 3A. (1237 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC102312030Fibroblast growth factor receptor substrate 2b. (525 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC102289294Fibroblast growth factor receptor. (836 aa)
LOC102304610Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
SPRY3Sprouty RTK signaling antagonist 3. (286 aa)
LOC102289408WAP domain-containing protein. (496 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
cblcCbl proto-oncogene C, E3 ubiquitin protein ligase. (601 aa)
LOC102301386Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
LOC102292008Uncharacterized protein. (458 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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