STRINGSTRING
fgf7 fgf7 LOC102312007 LOC102312007 PTBP3 PTBP3 polr2c polr2c grb2 grb2 ENSHBUP00000034273 ENSHBUP00000034273 ENSHBUP00000032881 ENSHBUP00000032881 ptbp2 ptbp2 LOC102301386 LOC102301386 LOC102304410 LOC102304410 cblc cblc fgf20 fgf20 LOC102314666 LOC102314666 esrp1 esrp1 ptbp1 ptbp1 SPRY3 SPRY3 LOC102304610 LOC102304610 KRAS KRAS hras hras LOC102289393 LOC102289393 FGF6-2 FGF6-2 fgf22 fgf22 gab1 gab1 fgf18 fgf18 uba52 uba52 LOC102312030 LOC102312030 tia1 tia1 mapk1 mapk1 fgf5 fgf5 shc1 shc1 ncbp2 ncbp2 gtf2f2 gtf2f2 polr2k polr2k fndc3a fndc3a LOC102303555 LOC102303555 esrp2 esrp2 LOC102304742 LOC102304742 polr2f polr2f ubb ubb ENSHBUP00000019390 ENSHBUP00000019390 ppp2ca ppp2ca NCBP1 NCBP1 LOC102302192 LOC102302192 fgf2 fgf2 spry2 spry2 CSDE1 CSDE1 LOC102310436 LOC102310436 LOC102307400 LOC102307400 polr2a polr2a POLR2B POLR2B cbl cbl LOC102307281 LOC102307281 fndc3b fndc3b polr2l polr2l fgf4 fgf4 fgf3 fgf3 FGF6 FGF6 SHC4 SHC4 fgf10 fgf10 LOC102305228 LOC102305228 tial1 tial1 polr2g polr2g POLR2E POLR2E LOC102309641 LOC102309641 fgfr2 fgfr2 fgf23 fgf23 ENSHBUP00000008412 ENSHBUP00000008412 PTBP2 PTBP2 polr2j polr2j gtf2f1 gtf2f1 LOC102296758 LOC102296758 LOC102313431 LOC102313431 LOC102289587 LOC102289587 polr2h polr2h ENSHBUP00000005111 ENSHBUP00000005111 ppp2cb ppp2cb LOC102305017 LOC102305017 plcg1 plcg1 mknk2 mknk2 fgfbp3 fgfbp3 pik3ca pik3ca polr2i polr2i LOC102303940 LOC102303940 SRC SRC rps27a rps27a LOC102303915 LOC102303915 ENSHBUP00000001164 ENSHBUP00000001164 LOC102290684 LOC102290684 LOC102296557 LOC102296557 LOC106633073 LOC106633073 fgf16 fgf16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
LOC102312007Heterogeneous nuclear ribonucleoprotein M. (648 aa)
PTBP3Polypyrimidine tract binding protein 3. (499 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
ENSHBUP00000034273Zgc:158659; Belongs to the PI3/PI4-kinase family. (485 aa)
ENSHBUP00000032881Fibroblast growth factor binding protein 1b. (219 aa)
ptbp2Polypyrimidine tract binding protein 2b. (523 aa)
LOC102301386Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
LOC102304410Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
cblcCbl proto-oncogene C, E3 ubiquitin protein ligase. (601 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
esrp1Epithelial splicing regulatory protein 1. (719 aa)
ptbp1Polypyrimidine tract binding protein 1a. (632 aa)
SPRY3Sprouty RTK signaling antagonist 3. (286 aa)
LOC102304610Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (217 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC102289393PH domain-containing protein. (543 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
gab1GRB2-associated binding protein 1. (746 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC102312030Fibroblast growth factor receptor substrate 2b. (525 aa)
tia1Cytotoxic granule-associated RNA binding protein 1, like. (386 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (191 aa)
gtf2f2General transcription factor IIF, polypeptide 2a. (248 aa)
polr2kPolymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
fndc3aFibronectin type III domain containing 3A. (1237 aa)
LOC102303555Uncharacterized protein. (387 aa)
esrp2Epithelial splicing regulatory protein 2. (716 aa)
LOC102304742Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
ENSHBUP00000019390Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (284 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
NCBP1Nuclear cap binding protein subunit 1. (795 aa)
LOC102302192Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
spry2Sprouty RTK signaling antagonist 2. (333 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (922 aa)
LOC102310436Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC102307400Zgc:55558. (187 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1906 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1088 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
LOC102307281Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
fndc3bFibronectin type III domain containing 3Ba. (1204 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SHC4SHC adaptor protein 4. (588 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
LOC102305228Uncharacterized protein. (857 aa)
tial1TIA1 cytotoxic granule-associated RNA binding protein-like 1. (379 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (181 aa)
POLR2ERNA polymerase II subunit E. (138 aa)
LOC102309641Fibroblast growth factor receptor substrate 3. (613 aa)
fgfr2Fibroblast growth factor receptor. (835 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)
ENSHBUP00000008412DDE_Tnp_1_7 domain-containing protein. (441 aa)
PTBP2Polypyrimidine tract binding protein 2a. (513 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (552 aa)
LOC102296758Tyrosine-protein kinase. (590 aa)
LOC102313431MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (462 aa)
LOC102289587DDE_Tnp_1_7 domain-containing protein. (578 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ENSHBUP00000005111Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
LOC102305017Heterogeneous nuclear ribonucleoprotein A1a. (333 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
fgfbp3Fibroblast growth factor binding protein 3. (251 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
polr2iPolymerase (RNA) II (DNA directed) polypeptide I. (135 aa)
LOC102303940Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
SRCTyrosine-protein kinase. (550 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC102303915General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (252 aa)
ENSHBUP00000001164RRM domain-containing protein. (151 aa)
LOC102290684Serine/threonine-protein phosphatase. (309 aa)
LOC102296557Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
LOC106633073Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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