55 items (Haplochromis burtoni) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106633073	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC102296557	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	ENSHBUP00000034273	Zgc:158659; Belongs to the PI3/PI4-kinase family. (485 aa)
	LOC102301386	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	LOC102304410	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	cblc	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (601 aa)
	fgf20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	LOC102314666	Ubiquitin-like domain-containing protein. (131 aa)
	SPRY3	Sprouty RTK signaling antagonist 3. (286 aa)
	LOC102304610	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (217 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	LOC102289393	PH domain-containing protein. (543 aa)
	gab1	GRB2-associated binding protein 1. (746 aa)
	fgf18	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC102312030	Fibroblast growth factor receptor substrate 2b. (525 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	fgf5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1237 aa)
	LOC102305018	Polypeptide N-acetylgalactosaminyltransferase. (619 aa)
	LOC102304742	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
	ubb	Ubiquitin-like domain-containing protein. (54 aa)
	ENSHBUP00000019390	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (284 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC102302192	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	spry2	Sprouty RTK signaling antagonist 2. (333 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (922 aa)
	LOC102310436	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC102307400	Zgc:55558. (187 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1204 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
	SHC4	SHC adaptor protein 4. (588 aa)
	LOC102305228	Uncharacterized protein. (857 aa)
	LOC102309641	Fibroblast growth factor receptor substrate 3. (613 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)
	ENSHBUP00000008412	DDE_Tnp_1_7 domain-containing protein. (441 aa)
	LOC102296758	Tyrosine-protein kinase. (590 aa)
	LOC102313431	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (462 aa)
	LOC102289587	DDE_Tnp_1_7 domain-containing protein. (578 aa)
	ENSHBUP00000005111	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	GALNT3	Polypeptide N-acetylgalactosaminyltransferase. (663 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
	mknk2	MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
	pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC102303940	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	SRC	Tyrosine-protein kinase. (550 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC102290684	Serine/threonine-protein phosphatase. (309 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSHBUP00000005111	ENSHBUP00000018081	ENSHBUP00000005111	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.550
CSDE1	ENSHBUP00000019390	ENSHBUP00000018081	ENSHBUP00000019390	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.723
CSDE1	ENSHBUP00000034273	ENSHBUP00000018081	ENSHBUP00000034273	Cold shock domain containing E1, RNA-binding.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.723
CSDE1	LOC102289393	ENSHBUP00000018081	ENSHBUP00000028120	Cold shock domain containing E1, RNA-binding.	PH domain-containing protein.	0.487
CSDE1	LOC102290684	ENSHBUP00000018081	ENSHBUP00000001048	Cold shock domain containing E1, RNA-binding.	Serine/threonine-protein phosphatase.	0.529
CSDE1	LOC102296557	ENSHBUP00000018081	ENSHBUP00000000782	Cold shock domain containing E1, RNA-binding.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.528
CSDE1	LOC102296758	ENSHBUP00000018081	ENSHBUP00000006069	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.647
CSDE1	LOC102301386	ENSHBUP00000018081	ENSHBUP00000032026	Cold shock domain containing E1, RNA-binding.	Protein phosphatase 2, regulatory subunit A, beta b.	0.585
CSDE1	LOC102302192	ENSHBUP00000018081	ENSHBUP00000018557	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.655
CSDE1	LOC102303940	ENSHBUP00000018081	ENSHBUP00000002371	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.545
CSDE1	LOC102304410	ENSHBUP00000018081	ENSHBUP00000031887	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.723
CSDE1	LOC102304610	ENSHBUP00000018081	ENSHBUP00000029550	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.566
CSDE1	LOC102304742	ENSHBUP00000018081	ENSHBUP00000019944	Cold shock domain containing E1, RNA-binding.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.528
CSDE1	LOC102305228	ENSHBUP00000018081	ENSHBUP00000010431	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.401
CSDE1	LOC102309641	ENSHBUP00000018081	ENSHBUP00000009195	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 3.	0.556
CSDE1	LOC102310436	ENSHBUP00000018081	ENSHBUP00000017819	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.565
CSDE1	LOC102312030	ENSHBUP00000018081	ENSHBUP00000025416	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 2b.	0.556
CSDE1	LOC102314666	ENSHBUP00000018081	ENSHBUP00000031002	Cold shock domain containing E1, RNA-binding.	Ubiquitin-like domain-containing protein.	0.689
CSDE1	LOC106633073	ENSHBUP00000018081	ENSHBUP00000000711	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.418
CSDE1	SHC4	ENSHBUP00000018081	ENSHBUP00000010980	Cold shock domain containing E1, RNA-binding.	SHC adaptor protein 4.	0.513