STRINGSTRING
xpc xpc LOC102300242 LOC102300242 wdr76 wdr76 LOC102292669 LOC102292669 LOC102307731 LOC102307731 ddb2 ddb2 rpa1 rpa1 xpa xpa cops3 cops3 ino80e ino80e LOC102314666 LOC102314666 usp45 usp45 rpa3 rpa3 pcna pcna LOC102311858 LOC102311858 LOC102293972 LOC102293972 rnf111 rnf111 cops2 cops2 cops4 cops4 rpap3 rpap3 sumo2 sumo2 kxd1 kxd1 rpa2 rpa2 uba52 uba52 ruvbl1 ruvbl1 gtf2h3 gtf2h3 pole pole cetn3 cetn3 LOC102302180 LOC102302180 chd1l chd1l COPS6 COPS6 LOC102305479 LOC102305479 LOC102313827 LOC102313827 LOC102312440 LOC102312440 RCBTB1 RCBTB1 tfpt tfpt ube2i ube2i nfrkb nfrkb mcrs1 mcrs1 kctd2 kctd2 ercc3 ercc3 SUMO3 SUMO3 rfc4 rfc4 ercc1 ercc1 vwa5b2 vwa5b2 mnat1 mnat1 ino80 ino80 ubb ubb meiob meiob ino80d ino80d gtf2h1 gtf2h1 gps1 gps1 pold1 pold1 cops5 cops5 RAD23B RAD23B LOC102299797 LOC102299797 pias1 pias1 rbx1 rbx1 YY1 YY1 cul4b cul4b cops7a cops7a ino80c ino80c LOC102294941 LOC102294941 rad23a rad23a ercc4 ercc4 pold4 pold4 LOC102289514 LOC102289514 LOC102292082 LOC102292082 LOC102312405 LOC102312405 LOC102299037 LOC102299037 rfc2 rfc2 actb actb bivm bivm ENSHBUP00000012005 ENSHBUP00000012005 LOC102313772 LOC102313772 LOC102303345 LOC102303345 parp3 parp3 cdk7 cdk7 actr5 actr5 pold2 pold2 rfc5 rfc5 wbp1 wbp1 parp1 parp1 sumo1 sumo1 ino80b ino80b ccnh ccnh pole4 pole4 LOC102297270 LOC102297270 RPA1 RPA1 polk polk pole2 pole2 ddb1 ddb1 pold3 pold3 gtf2h5 gtf2h5 ube2v2 ube2v2 parp2 parp2 rfc3 rfc3 ENSHBUP00000004241 ENSHBUP00000004241 actr8 actr8 rps27a rps27a rfc1 rfc1 ENSHBUP00000001804 ENSHBUP00000001804 gtf2h4 gtf2h4 ercc2 ercc2 LOC102296485 LOC102296485 cul4a cul4a LOC102288768 LOC102288768 ercc5 ercc5 cops8 cops8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
xpcXeroderma pigmentosum, complementation group C. (874 aa)
LOC102300242YY1 transcription factor. (358 aa)
wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (549 aa)
LOC102292669General transcription factor IIH subunit. (392 aa)
LOC102307731Centrin 4. (171 aa)
ddb2Damage-specific DNA binding protein 2. (490 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
xpaXeroderma pigmentosum, complementation group A. (271 aa)
cops3COP9 signalosome subunit 3. (423 aa)
ino80eINO80 complex subunit E. (236 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
usp45Ubiquitin carboxyl-terminal hydrolase. (809 aa)
rpa3Replication protein A3. (122 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
LOC102311858Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC102293972Uncharacterized protein. (404 aa)
rnf111Ring finger protein 111. (1006 aa)
cops2COP9 signalosome subunit 2. (443 aa)
cops4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (321 aa)
rpap3RNA polymerase II associated protein 3. (632 aa)
sumo2Ubiquitin-like domain-containing protein. (143 aa)
kxd1KxDL motif containing 1. (184 aa)
rpa2Replication protein A2. (293 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (462 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (305 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2016 aa)
cetn3Centrin 3. (167 aa)
LOC102302180Uncharacterized protein. (471 aa)
chd1lChromodomain helicase DNA binding protein 1-like. (994 aa)
COPS6COP9 signalosome subunit 6. (346 aa)
LOC102305479Uncharacterized protein. (381 aa)
LOC102313827Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (591 aa)
LOC102312440Small ubiquitin-related modifier. (94 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
tfptTCF3 (E2A) fusion partner. (199 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
nfrkbNuclear factor related to kappaB binding protein. (1274 aa)
mcrs1Microspherule protein 1. (466 aa)
kctd2Potassium channel tetramerization domain containing 2. (272 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
SUMO3Small ubiquitin-related modifier. (94 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
ercc1Excision repair cross-complementation group 1. (352 aa)
vwa5b2Von Willebrand factor A domain containing 5B2. (1401 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
ino80INO80 complex ATPase subunit. (1497 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
meiobMethionine sulfoxide reductase B1b. (464 aa)
ino80dINO80 complex subunit Da. (1007 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
gps1G protein pathway suppressor 1. (487 aa)
pold1DNA polymerase. (1129 aa)
cops5COP9 signalosome subunit 5. (334 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (379 aa)
LOC102299797Actin, beta 1. (375 aa)
pias1Protein inhibitor of activated STAT, 1b. (663 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
YY1YY1 transcription factor b. (369 aa)
cul4bCullin 4B; Belongs to the cullin family. (865 aa)
cops7aCOP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
ino80cINO80 complex subunit C. (203 aa)
LOC102294941Small ubiquitin-related modifier. (96 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (378 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
pold4Si:dkey-28b4.7. (107 aa)
LOC102289514UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (182 aa)
LOC102292082Protein inhibitor of activated STAT, 1a. (710 aa)
LOC102312405ATPase family AAA domain containing 5a. (1808 aa)
LOC102299037UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
rfc2Replication factor C (activator 1) 2. (356 aa)
actbUncharacterized protein. (377 aa)
bivmBasic, immunoglobulin-like variable motif containing. (496 aa)
ENSHBUP00000012005Uncharacterized protein. (75 aa)
LOC102313772Uncharacterized protein; Belongs to the actin family. (285 aa)
LOC102303345Uncharacterized protein; Belongs to the actin family. (263 aa)
parp3Poly [ADP-ribose] polymerase. (559 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
actr5Actin related protein 5; Belongs to the actin family. (624 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (481 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
wbp1Uncharacterized protein. (529 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
sumo1Small ubiquitin like modifier 1. (129 aa)
ino80bINO80 complex subunit B. (342 aa)
ccnhCyclin H; Belongs to the cyclin family. (335 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
LOC102297270SCY domain-containing protein. (125 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
polkPolymerase (DNA directed) kappa. (875 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (532 aa)
ddb1Damage-specific DNA binding protein 1. (1140 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (444 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
parp2Poly [ADP-ribose] polymerase. (528 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
ENSHBUP00000004241Polymerase (DNA directed), epsilon 3 (p17 subunit). (147 aa)
actr8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (643 aa)
rps27aRibosomal protein S27a. (156 aa)
rfc1BRCT domain-containing protein. (471 aa)
ENSHBUP00000001804RFC1 domain-containing protein. (135 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
LOC102296485Si:ch73-290k24.6. (845 aa)
cul4aCullin 4A; Belongs to the cullin family. (692 aa)
LOC102288768Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
ercc5Excision repair cross-complementation group 5. (1113 aa)
cops8COP9 signalosome subunit 8. (191 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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