STRINGSTRING
ercc5 ercc5 LOC102288768 LOC102288768 cul4a cul4a ercc2 ercc2 gtf2h4 gtf2h4 ENSHBUP00000001804 ENSHBUP00000001804 rfc1 rfc1 rps27a rps27a ENSHBUP00000004241 ENSHBUP00000004241 rfc3 rfc3 parp2 parp2 gtf2h5 gtf2h5 pold3 pold3 ddb1 ddb1 pole2 pole2 polk polk RPA1 RPA1 pole4 pole4 parp1 parp1 rfc5 rfc5 pold2 pold2 parp3 parp3 bivm bivm rfc2 rfc2 pold4 pold4 ercc4 ercc4 cul4b cul4b rbx1 rbx1 pold1 pold1 gtf2h1 gtf2h1 ubb ubb ercc1 ercc1 rfc4 rfc4 ercc3 ercc3 RCBTB1 RCBTB1 LOC102313827 LOC102313827 chd1l chd1l pole pole gtf2h3 gtf2h3 uba52 uba52 rpa2 rpa2 kxd1 kxd1 pcna pcna rpa3 rpa3 LOC102314666 LOC102314666 xpa xpa rpa1 rpa1 ddb2 ddb2 LOC102292669 LOC102292669
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ercc5Excision repair cross-complementation group 5. (1113 aa)
LOC102288768Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
cul4aCullin 4A; Belongs to the cullin family. (692 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
ENSHBUP00000001804RFC1 domain-containing protein. (135 aa)
rfc1BRCT domain-containing protein. (471 aa)
rps27aRibosomal protein S27a. (156 aa)
ENSHBUP00000004241Polymerase (DNA directed), epsilon 3 (p17 subunit). (147 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
parp2Poly [ADP-ribose] polymerase. (528 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (444 aa)
ddb1Damage-specific DNA binding protein 1. (1140 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (532 aa)
polkPolymerase (DNA directed) kappa. (875 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (481 aa)
parp3Poly [ADP-ribose] polymerase. (559 aa)
bivmBasic, immunoglobulin-like variable motif containing. (496 aa)
rfc2Replication factor C (activator 1) 2. (356 aa)
pold4Si:dkey-28b4.7. (107 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
cul4bCullin 4B; Belongs to the cullin family. (865 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
pold1DNA polymerase. (1129 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
ercc1Excision repair cross-complementation group 1. (352 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
LOC102313827Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (591 aa)
chd1lChromodomain helicase DNA binding protein 1-like. (994 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2016 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (305 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
rpa2Replication protein A2. (293 aa)
kxd1KxDL motif containing 1. (184 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
rpa3Replication protein A3. (122 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
xpaXeroderma pigmentosum, complementation group A. (271 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
ddb2Damage-specific DNA binding protein 2. (490 aa)
LOC102292669General transcription factor IIH subunit. (392 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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