61 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cops8	COP9 signalosome subunit 8. (191 aa)
	cul4a	Cullin 4A; Belongs to the cullin family. (692 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	hmgn5	High mobility group nucleosome binding domain 6. (87 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	polr2i	Polymerase (RNA) II (DNA directed) polypeptide I. (135 aa)
	uvssa	UV-stimulated scaffold protein A. (684 aa)
	tceanc2	Uncharacterized protein. (260 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	ZNF830	Zinc finger protein 830. (347 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
	ddb1	Damage-specific DNA binding protein 1. (1140 aa)
	ENSHBUP00000007438	Uncharacterized protein. (88 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (335 aa)
	POLR2E	RNA polymerase II subunit E. (138 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (181 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
	cops7a	COP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
	nrde2	NRDE-2, necessary for RNA interference, domain containing. (1186 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (865 aa)
	polr2d	RPOL4c domain-containing protein. (509 aa)
	ep300	E1A binding protein p300 b. (2764 aa)
	POLR2B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1088 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1906 aa)
	ppp1r42	Protein phosphatase 1, regulatory subunit 42. (276 aa)
	cops5	COP9 signalosome subunit 5. (334 aa)
	gps1	G protein pathway suppressor 1. (487 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (302 aa)
	ENSHBUP00000018586	TFIIS N-terminal domain-containing protein. (406 aa)
	ubb	Ubiquitin-like domain-containing protein. (54 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
	LOC102296285	Transcription elongation factor A (SII), 2. (331 aa)
	ercc6	Excision repair cross-complementation group 6. (1439 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	LOC102306757	E1A binding protein p300 a. (2600 aa)
	polr2k	Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	ercc8	Excision repair cross-complementation group 8. (412 aa)
	COPS6	COP9 signalosome subunit 6. (346 aa)
	LOC102302266	Si:ch73-1a9.3. (84 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (305 aa)
	prpf19	Pre-mRNA processing factor 19. (505 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	tcea1	Transcription elongation factor A (SII), 1. (311 aa)
	cops4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (321 aa)
	cops2	COP9 signalosome subunit 2. (443 aa)
	TCEANC	Transcription elongation factor A N-terminal and central domain containing. (345 aa)
	LOC102314666	Ubiquitin-like domain-containing protein. (131 aa)
	cops3	COP9 signalosome subunit 3. (423 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (271 aa)
	aqr	Aquarius intron-binding spliceosomal factor. (1472 aa)
	LOC102292669	General transcription factor IIH subunit. (392 aa)
	xab2	XPA binding protein 2. (849 aa)
	polr2c	Polymerase (RNA) II (DNA directed) polypeptide C. (275 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPS6	ENSHBUP00000018586	ENSHBUP00000025144	ENSHBUP00000018586	COP9 signalosome subunit 6.	TFIIS N-terminal domain-containing protein.	0.456
COPS6	LOC102292669	ENSHBUP00000025144	ENSHBUP00000034401	COP9 signalosome subunit 6.	General transcription factor IIH subunit.	0.670
COPS6	LOC102296285	ENSHBUP00000025144	ENSHBUP00000020190	COP9 signalosome subunit 6.	Transcription elongation factor A (SII), 2.	0.456
COPS6	LOC102314666	ENSHBUP00000025144	ENSHBUP00000031002	COP9 signalosome subunit 6.	Ubiquitin-like domain-containing protein.	0.839
COPS6	POLR2B	ENSHBUP00000025144	ENSHBUP00000015581	COP9 signalosome subunit 6.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.757
COPS6	POLR2E	ENSHBUP00000025144	ENSHBUP00000009323	COP9 signalosome subunit 6.	RNA polymerase II subunit E.	0.753
COPS6	TCEANC	ENSHBUP00000025144	ENSHBUP00000028659	COP9 signalosome subunit 6.	Transcription elongation factor A N-terminal and central domain containing.	0.456
COPS6	ccnh	ENSHBUP00000025144	ENSHBUP00000008328	COP9 signalosome subunit 6.	Cyclin H; Belongs to the cyclin family.	0.689
COPS6	cops2	ENSHBUP00000025144	ENSHBUP00000028598	COP9 signalosome subunit 6.	COP9 signalosome subunit 2.	0.999
COPS6	cops3	ENSHBUP00000025144	ENSHBUP00000031395	COP9 signalosome subunit 6.	COP9 signalosome subunit 3.	0.999
COPS6	cops4	ENSHBUP00000025144	ENSHBUP00000028387	COP9 signalosome subunit 6.	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).	0.999
COPS6	cops5	ENSHBUP00000025144	ENSHBUP00000017010	COP9 signalosome subunit 6.	COP9 signalosome subunit 5.	0.998
COPS6	cops7a	ENSHBUP00000025144	ENSHBUP00000014816	COP9 signalosome subunit 6.	COP9 constitutive photomorphogenic homolog subunit 7A.	0.995
COPS6	cops8	ENSHBUP00000025144	ENSHBUP00000000049	COP9 signalosome subunit 6.	COP9 signalosome subunit 8.	0.997
COPS6	cul4a	ENSHBUP00000025144	ENSHBUP00000000595	COP9 signalosome subunit 6.	Cullin 4A; Belongs to the cullin family.	0.929
COPS6	cul4b	ENSHBUP00000025144	ENSHBUP00000015278	COP9 signalosome subunit 6.	Cullin 4B; Belongs to the cullin family.	0.929
COPS6	ddb1	ENSHBUP00000025144	ENSHBUP00000007296	COP9 signalosome subunit 6.	Damage-specific DNA binding protein 1.	0.933
COPS6	ercc2	ENSHBUP00000025144	ENSHBUP00000000975	COP9 signalosome subunit 6.	Excision repair cross-complementation group 2.	0.707
COPS6	ercc3	ENSHBUP00000025144	ENSHBUP00000023151	COP9 signalosome subunit 6.	Excision repair cross-complementation group 3.	0.684
COPS6	ercc6	ENSHBUP00000025144	ENSHBUP00000020553	COP9 signalosome subunit 6.	Excision repair cross-complementation group 6.	0.728