STRINGSTRING
ZNF830 ZNF830 xab2 xab2 LOC102292669 LOC102292669 xrcc1 xrcc1 rpa1 rpa1 aqr aqr xpa xpa cops3 cops3 LOC102314666 LOC102314666 rpa3 rpa3 pcna pcna lig3 lig3 TCEANC TCEANC cops2 cops2 cops4 cops4 tcea1 tcea1 kxd1 kxd1 rpa2 rpa2 uba52 uba52 prpf19 prpf19 gtf2h3 gtf2h3 LOC102302266 LOC102302266 pole pole COPS6 COPS6 LOC102313827 LOC102313827 RCBTB1 RCBTB1 ercc8 ercc8 ercc3 ercc3 rfc4 rfc4 ercc1 ercc1 polr2k polr2k LOC102306757 LOC102306757 mnat1 mnat1 ercc6 ercc6 LOC102296285 LOC102296285 polr2f polr2f ubb ubb ENSHBUP00000018586 ENSHBUP00000018586 meiob meiob ppie ppie gtf2h1 gtf2h1 gps1 gps1 pold1 pold1 cops5 cops5 ppp1r42 ppp1r42 polr2a polr2a rbx1 rbx1 POLR2B POLR2B ep300 ep300 polr2d polr2d cul4b cul4b nrde2 nrde2 cops7a cops7a usp7 usp7 ercc4 ercc4 pold4 pold4 LOC102312405 LOC102312405 rfc2 rfc2 polr2l polr2l bivm bivm cdk7 cdk7 polr2g polr2g POLR2E POLR2E pold2 pold2 rfc5 rfc5 ccnh ccnh pole4 pole4 LOC102297270 LOC102297270 RPA1 RPA1 polk polk ENSHBUP00000007438 ENSHBUP00000007438 pole2 pole2 ddb1 ddb1 pold3 pold3 polr2j polr2j lig1 lig1 phf3 phf3 gtf2h5 gtf2h5 usp40 usp40 polr2h polr2h tceanc2 tceanc2 rfc3 rfc3 ENSHBUP00000004241 ENSHBUP00000004241 uvssa uvssa polr2i polr2i rps27a rps27a rfc1 rfc1 ENSHBUP00000001804 ENSHBUP00000001804 gtf2h4 gtf2h4 hmgn5 hmgn5 ercc2 ercc2 cul4a cul4a LOC102288768 LOC102288768 ercc5 ercc5 cops8 cops8 polr2c polr2c
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZNF830Zinc finger protein 830. (347 aa)
xab2XPA binding protein 2. (849 aa)
LOC102292669General transcription factor IIH subunit. (392 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
aqrAquarius intron-binding spliceosomal factor. (1472 aa)
xpaXeroderma pigmentosum, complementation group A. (271 aa)
cops3COP9 signalosome subunit 3. (423 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
rpa3Replication protein A3. (122 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
lig3DNA ligase. (1012 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (345 aa)
cops2COP9 signalosome subunit 2. (443 aa)
cops4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (321 aa)
tcea1Transcription elongation factor A (SII), 1. (311 aa)
kxd1KxDL motif containing 1. (184 aa)
rpa2Replication protein A2. (293 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
prpf19Pre-mRNA processing factor 19. (505 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (305 aa)
LOC102302266Si:ch73-1a9.3. (84 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2016 aa)
COPS6COP9 signalosome subunit 6. (346 aa)
LOC102313827Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (591 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
ercc8Excision repair cross-complementation group 8. (412 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
ercc1Excision repair cross-complementation group 1. (352 aa)
polr2kPolymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
LOC102306757E1A binding protein p300 a. (2600 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
ercc6Excision repair cross-complementation group 6. (1439 aa)
LOC102296285Transcription elongation factor A (SII), 2. (331 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
ENSHBUP00000018586TFIIS N-terminal domain-containing protein. (406 aa)
meiobMethionine sulfoxide reductase B1b. (464 aa)
ppiePeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (302 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
gps1G protein pathway suppressor 1. (487 aa)
pold1DNA polymerase. (1129 aa)
cops5COP9 signalosome subunit 5. (334 aa)
ppp1r42Protein phosphatase 1, regulatory subunit 42. (276 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1906 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1088 aa)
ep300E1A binding protein p300 b. (2764 aa)
polr2dRPOL4c domain-containing protein. (509 aa)
cul4bCullin 4B; Belongs to the cullin family. (865 aa)
nrde2NRDE-2, necessary for RNA interference, domain containing. (1186 aa)
cops7aCOP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
pold4Si:dkey-28b4.7. (107 aa)
LOC102312405ATPase family AAA domain containing 5a. (1808 aa)
rfc2Replication factor C (activator 1) 2. (356 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
bivmBasic, immunoglobulin-like variable motif containing. (496 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (181 aa)
POLR2ERNA polymerase II subunit E. (138 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (481 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ccnhCyclin H; Belongs to the cyclin family. (335 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
LOC102297270SCY domain-containing protein. (125 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
polkPolymerase (DNA directed) kappa. (875 aa)
ENSHBUP00000007438Uncharacterized protein. (88 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (532 aa)
ddb1Damage-specific DNA binding protein 1. (1140 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (444 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
lig1DNA ligase. (1012 aa)
phf3PHD finger protein 3. (1704 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
usp40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1290 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
tceanc2Uncharacterized protein. (260 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
ENSHBUP00000004241Polymerase (DNA directed), epsilon 3 (p17 subunit). (147 aa)
uvssaUV-stimulated scaffold protein A. (684 aa)
polr2iPolymerase (RNA) II (DNA directed) polypeptide I. (135 aa)
rps27aRibosomal protein S27a. (156 aa)
rfc1BRCT domain-containing protein. (471 aa)
ENSHBUP00000001804RFC1 domain-containing protein. (135 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
hmgn5High mobility group nucleosome binding domain 6. (87 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
cul4aCullin 4A; Belongs to the cullin family. (692 aa)
LOC102288768Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
ercc5Excision repair cross-complementation group 5. (1113 aa)
cops8COP9 signalosome subunit 8. (191 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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