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ercc2 ercc2 polr2g polr2g LOC102288768 LOC102288768 cul4a cul4a cdk7 cdk7 polr2l polr2l rfc2 rfc2 LOC102312405 LOC102312405 pold4 pold4 usp7 usp7 nrde2 nrde2 cul4b cul4b polr2d polr2d ep300 ep300 POLR2B POLR2B rbx1 rbx1 polr2a polr2a pold1 pold1 gtf2h1 gtf2h1 ppie ppie meiob meiob ENSHBUP00000018586 ENSHBUP00000018586 ubb ubb polr2f polr2f LOC102296285 LOC102296285 ercc6 ercc6 mnat1 mnat1 LOC102306757 LOC102306757 polr2k polr2k rfc4 rfc4 ercc3 ercc3 ercc8 ercc8 RCBTB1 RCBTB1 LOC102313827 LOC102313827 pole pole LOC102302266 LOC102302266 gtf2h3 gtf2h3 prpf19 prpf19 uba52 uba52 rpa2 rpa2 kxd1 kxd1 tcea1 tcea1 TCEANC TCEANC lig3 lig3 pcna pcna rpa3 rpa3 LOC102314666 LOC102314666 aqr aqr rpa1 rpa1 xrcc1 xrcc1 LOC102292669 LOC102292669 xab2 xab2 polr2c polr2c POLR2E POLR2E pold2 pold2 rfc5 rfc5 ccnh ccnh pole4 pole4 RPA1 RPA1 polk polk ENSHBUP00000007438 ENSHBUP00000007438 pole2 pole2 ddb1 ddb1 pold3 pold3 polr2j polr2j lig1 lig1 phf3 phf3 gtf2h5 gtf2h5 ZNF830 ZNF830 usp40 usp40 polr2h polr2h tceanc2 tceanc2 rfc3 rfc3 ENSHBUP00000004241 ENSHBUP00000004241 uvssa uvssa polr2i polr2i rps27a rps27a rfc1 rfc1 ENSHBUP00000001804 ENSHBUP00000001804 gtf2h4 gtf2h4 hmgn5 hmgn5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ercc2Excision repair cross-complementation group 2. (760 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (181 aa)
LOC102288768Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
cul4aCullin 4A; Belongs to the cullin family. (692 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
rfc2Replication factor C (activator 1) 2. (356 aa)
LOC102312405ATPase family AAA domain containing 5a. (1808 aa)
pold4Si:dkey-28b4.7. (107 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
nrde2NRDE-2, necessary for RNA interference, domain containing. (1186 aa)
cul4bCullin 4B; Belongs to the cullin family. (865 aa)
polr2dRPOL4c domain-containing protein. (509 aa)
ep300E1A binding protein p300 b. (2764 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1088 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1906 aa)
pold1DNA polymerase. (1129 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
ppiePeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (302 aa)
meiobMethionine sulfoxide reductase B1b. (464 aa)
ENSHBUP00000018586TFIIS N-terminal domain-containing protein. (406 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
LOC102296285Transcription elongation factor A (SII), 2. (331 aa)
ercc6Excision repair cross-complementation group 6. (1439 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
LOC102306757E1A binding protein p300 a. (2600 aa)
polr2kPolymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
ercc8Excision repair cross-complementation group 8. (412 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
LOC102313827Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (591 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2016 aa)
LOC102302266Si:ch73-1a9.3. (84 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (305 aa)
prpf19Pre-mRNA processing factor 19. (505 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
rpa2Replication protein A2. (293 aa)
kxd1KxDL motif containing 1. (184 aa)
tcea1Transcription elongation factor A (SII), 1. (311 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (345 aa)
lig3DNA ligase. (1012 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
rpa3Replication protein A3. (122 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
aqrAquarius intron-binding spliceosomal factor. (1472 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa)
LOC102292669General transcription factor IIH subunit. (392 aa)
xab2XPA binding protein 2. (849 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
POLR2ERNA polymerase II subunit E. (138 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (481 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ccnhCyclin H; Belongs to the cyclin family. (335 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
polkPolymerase (DNA directed) kappa. (875 aa)
ENSHBUP00000007438Uncharacterized protein. (88 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (532 aa)
ddb1Damage-specific DNA binding protein 1. (1140 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (444 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
lig1DNA ligase. (1012 aa)
phf3PHD finger protein 3. (1704 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
ZNF830Zinc finger protein 830. (347 aa)
usp40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1290 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
tceanc2Uncharacterized protein. (260 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
ENSHBUP00000004241Polymerase (DNA directed), epsilon 3 (p17 subunit). (147 aa)
uvssaUV-stimulated scaffold protein A. (684 aa)
polr2iPolymerase (RNA) II (DNA directed) polypeptide I. (135 aa)
rps27aRibosomal protein S27a. (156 aa)
rfc1BRCT domain-containing protein. (471 aa)
ENSHBUP00000001804RFC1 domain-containing protein. (135 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
hmgn5High mobility group nucleosome binding domain 6. (87 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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